Patch

Berlex

Climara Patch (estradiol) is used for the treatment of menopausal and postmenopausal symptoms in women.

Do not use Climara Patch (estradiol) if you are allergic to this or similar medicines or to any ingredient present in Climara Patch (estradiol), known or suspected estrogen-dependent neoplasia such as breast or endometrial cancer; endometrial hyperplasia; undiagnosed vaginal bleeding; active liver dysfunction or disease, especially of the obstructive type; active thrombophlebitis, thrombosis or thrombotic disorders; a history of cerebrovascular accident, coronary thrombosis, or in the presence of classical migraine; a history of thrombophlebitis, thrombosis or thromboembolic disorders associated with previous estrogen use; partial or complete loss of vision from ophthalmic vascular disease

Before using Climara Patch (estradiol), tell your health care provider about any of the following: if you are pregnant, planning to become pregnant, or breastfeeding if you are taking any prescription or nonprescription medicine if you are taking any herbal products, if you are taking blood thinners if you have stomach problems if you have peptic ulcers if you have any other medical condition like liver or kidney function impairment, heart ot lung problem, if you have epilepsy or asthma.

Contact sensitization is known to occur with topical applications. Although it is extremely rare, patients who develop contact sensitization to any component of the patch should be warned that a severe hypersensitivity reaction may occur with continuing exposure to the causative agent.

Other: Palpitation, thrombophlebitis, pulmonary embolism, varicose veins, increase in blood pressure, increase or decrease in weight, edema, changes in libido, musculoskeletal pain.

If you have any questions about the amount and/or frequency of Climara Patch (estradiol) you are taking, talk with your health care provider. Do not stop taking Climara Patch (estradiol) without checking with your health care provider. Patients with previous medical conditions should talk with their health care provider before taking Climara Patch (estradiol). Do not take more medicine than prescribed unless advised to do so by your health care provider. Do not take any other over-the-counter or prescription medications without talking with your health care provider. If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. If more than one dose is missed, contact your health care provider or pharmacist. Patch Application: The physician should discuss the most appropriate placement of the patch with the patient. Immediately after removal of a patch from the pouch and removal of the protective liner, the adhesive side of the patch should be placed on a clean, dry area of intact skin. The area selected should not be oily, damaged or irritated, and not exposed to the sun. The site selected should also be one at which little wrinking of the skin occurs during movement of the body, preferably the buttocks, lower abdomen or hip. The patch may also be placed on the side or lower back. The patch should be placed consistently on the same area of the body with each application (e.g., either the buttocks, lower abdomen, hip, side or lower back). Experience to date has shown that less irritation of the skin occurs on the buttocks than on other sites of application. Therefore, it is advisable to apply the patch to the buttocks. The waistline should be avoided, since tight clothing may dislodge the patch. The patch should be pressed firmly in place with the palm of the hand, making sure there is good contact, especially around the edges. In the event that a patch should fall off, it can be reapplied. If it fails to adhere then a new patch may be applied. In either case, the original treatment schedule should be continued. Patches should not be applied to the same skin site twice in succession. This patch must not be applied to the breasts to avoid potentially harmful effects on the breast tissue.

Store Climara Patch (estradiol) in a dry place at room temperature between 59° - 86°F. Keep out of reach of children and pets