Regranex (becaplermin) is used to help heal foot ulcers caused by diabetes.

Do not take Regranex (becaplermin) if you are allergic to any ingredient in Regranex (becaplermin) you are aware of tumors or abnormal growths at the application site

Before using Regranex (becaplermin), tell your health care provider about any of the following: if you are pregnant, planning to become pregnant, or breastfeeding if you are taking any other prescription or nonprescription medicine if you have any other medical condition

How much medicine you take and how often you take it depends on many factors, including the condition being treated and the age and weight of the patient and the size of the ulcer. If you have any questions about the amount and/or frequency of Regranex (becaplermin) you are taking, talk with your health care provider. Wash hands thoroughly before applying. Make sure the tip of the tube does not touch the ulcer or any other surface; replace cap on tube tightly after each use. Apply medicine with a tongue depressor or other application aid. Squeeze recommended length of gel, prescribed by your doctor, onto a clean, firm, non-absorbable surface such as wax paper. Spread the measured gel over the ulcer surface evenly with the application aid. Cover with a saline-moistened gauge dressing that only covers the wound, not the surrounding healthy skin. Wrap a gauze bandage over the dressing. After 12 hours, the ulcer should be gently rinsed with saline or water to remove remaining gel. Cover with saline-moistened gauze dressing. Do not use any other creams, gels, or other ointments at the site of the wound. If you feel any discomfort, talk with your doctor or health care provider immediately. Do not stop using Regranex (becaplermin) without checking with your doctor. Do not use more medication than prescribed unless advised to do so by your doctor or health care provider. As the ulcer heals, the amount of medication used may be less according to your doctor's instructions. Do not take any other over-the-counter or prescription medications without talking with your doctor. If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your doctor. Simply skip the missed dose and continue with the next scheduled dose. If more than one dose is missed, contact your doctor or pharmacist.

Store Regranex (becaplermin) in refrigerator between 36 to 46 degrees F. Do not freeze. Do not use gel after the expiration date at the bottom of the tube.