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 Trilafon (perphenazine) Information

Formulation:

Tablet

Manufacturer:

Apotex

Alternate Names:

Trilafon (perphenazine)

 

What is Trilafon (perphenazine) used for?

Trilafon (perphenazine) is used to improve psychotic behavior in conditions such as schizophrenia. It is also used to control severe nausea and vomiting in adults.

When should Trilafon (perphenazine) not be taken?

Do not take Trilafon (perphenazine) if you are allergic to any ingredient in Trilafon (perphenazine), sulfites, or to similar medications you have been sedated you are currently taking large doses of alcohol, painkillers, or antihistamines you have brain damage you have blood disorders you have liver or kidney damage you have an inability to fight infection

What precautions should I follow when taking Trilafon (perphenazine) ?

Before using Trilafon (perphenazine), tell your health care provider about any of the following: if you are pregnant, planning to become pregnant, or breastfeeding if you are taking any prescription or nonprescription medicine if you have a history of convulsions if you have a history of depression if you have or history of any other medical condition like breast cancer, kidney, heart, liver or lung disease or breast cancer.

What special warning(s) should I be aware of when taking Trilafon (perphenazine)?

Trilafon (perphenazine) is capable of triggering a potentially fatal condition known as Neuroleptic Malignant Syndrome. Symptoms include high fever, muscle rigidity, altered mental status, unstable blood pressure, a rapid or irregular heartbeat, and excessive sweating. If any of these symptoms develop, see your health care provider immediately and discontinue treatment with Trilafon (perphenazine).

What are the side effects of Trilafon (perphenazine)?

Most severe:ÿ Involuntary and uncontrollable muscle movements (including the tongue, face, and mouth); tightness in the throat or jaw; numbness of the arms and legs; mental confusion; vision problems; seizures.
Most common:ÿ Headache; dizziness; drowsiness; confusion; tired feeling; sleeplessness; dry mouth; nausea; vomiting; diarrhea; appetite loss; constipation.
Other:ÿ Urinary changes; stuffy nose; itching; hives; dry skin; sweating; changes in breasts; menstrual problems; changes in sex drive; skin discoloration. Withdrawal symptoms (eg, stomach pain, nausea, vomiting, dizziness, shakiness) have occurred in patients on high doses of Trilafon (perphenazine) who suddenly stop taking it. Talk with your doctor before you stop taking Trilafon (perphenazine). However, in general, Trilafon (perphenazine) does not cause any type of mental dependence.

How should I take Trilafon (perphenazine)?

How much medicine you take and how often you take it depend on many factors, including the condition being treated and the age and weight of the patient. If you have any questions about the amount and/or frequency of Trilafon (perphenazine) you are taking, talk with your health care provider. Do not drink alcohol or take central nervous depressants (eg, antihistamines, narcotics, barbiturates, atropine) while taking Trilafon (perphenazine). Close medical supervision is necessary while taking Trilafon (perphenazine). Trilafon (perphenazine) may cause drowsiness or dizziness, especially during the first or second week. Use caution while driving or performing other tasks requiring alertness, coordination, or physical dexterity. If dizziness, lightheadedness, or fainting occurs, get up slowly and avoid sudden changes in postures. Trilafon (perphenazine) may cause sensitivity to light. Use sunscreens and wear protective clothing until tolerance is known. Trilafon (perphenazine) should not be used in children under 12 years of age. Involuntary and uncontrollable muscle movements may develop in patients, being treated with Trilafon (perphenazine). Discuss this possibility with your health care provider. A potentially fatal syndrome called neuroleptic malignant syndrome (NMS) has been associated with Trilafon (perphenazine). Symptoms include the following: Increased body heat; rigid muscles; changes in mental abilities; irregular pulse and blood pressure; increased heart rate; sweating; irregular heart rhythm. Tell your doctor at once if any of these occur. Lab tests may be required to monitor therapy. Be sure to keep appointments. Do not stop taking Trilafon (perphenazine) without checking with your health care provider. Patients with previous medical conditions should talk with their health care provider before taking Trilafon (perphenazine). Do not take more medicine than is prescribed unless advised to do so by your health care provider. Do not take any other over-the-counter or prescription medications without talking with your health care provider. If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. If more than one dose is missed, contact your health care provider or pharmacist.

How should Trilafon (perphenazine) be stored?

Store Trilafon (perphenazine) between 36 to 77 degrees F. Store in the original container or in a tight, light resistant container.

General Information:

If you have any questions about Trilafon (perphenazine), please talk with your doctor, pharmacist, or health care provider. Trilafon (perphenazine) is only to be used by the patient for whom it is prescribed. Do not give it to others. This information is advisory only. It does not contain all information about Trilafon (perphenazine). If you have any questions about Trilafon (perphenazine), ask your doctor, pharmacist, or health care provider.
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