What is Nozinan/Methotrimeprazine used for?

This medicine is used to treat anxiety states such as acute and chronic schizophrenias, senile psychoses, manic-depressive syndromes.

If you have any questions about your medicine, please talk with your health care provider, pharmacist, or health care provider. This medicine is only to be used by the patient for whom it is prescribed. Do not give it to others. This information is advisory only. It does not contain all information about this medicine. If you have any questions about your medicine, ask your health care provider, pharmacist, or health care provider.

How should Nozinan/Methotrimeprazine be stored?

Store in a cool, dry palce. Protect from moisture. Keep out of the reach of children and pets.

General drug information:

When should Nozinan/Methotrimeprazine not be taken?

Do not take this medicine if you are allergic to any ingredient in this medicine or similar medications if you are allergic to phenothiazines if you have liver or blood disease.

What precautions should I follow when taking Nozinan/Methotrimeprazine?

Before using this medicine, tell your health care provider about any of the following: if you are pregnant, planning to become pregnant, or breastfeeding if you are taking any prescription or nonprescription medicine if you have any other medical condit

What special warning(s) should I be aware of when taking Nozinan/Methotrimeprazine?

This medicine can reduce psychomotor activity especially during the first few days of treatment. Patients should therefore be cautioned not to drive a motor vehicle or to participate in activities requiring total mental alertness. This medicine should be used with caution in pregnant women, particularly during the first trimester, unless the benefit to the patient outweighs any possible risk to the fetus.

What are the side effects of Nozinan/Methotrimeprazine?

Most severe: Spasms, tremor or tonic and clonic convulsions, coma accompanied by hypotension and respiratory depression

Most common: Drowsiness, low blood pressure, weight gain, skin allergy, photo-sensitivity, jaundice, liver damage

Other: None

How should I take Nozinan/Methotrimeprazine?

How much medicine you take and how often you take it depends on many factors, including the condition being treated and the age and weight of the patient. If you have any questions about the amount and/or frequency of the medicine you are taking, talk with your health care provider. Carefully read the information provided with this medicine and reread it each time you get this prescription refilled. Take this medicine exactly as prescribed by your health care provider. You must carefully follow the cholesterol-lowering diet given to you by your health care provider. Contact your health care provider if unexplained muscle pain, tenderness, or weakness occur, especially if accompanied by general body discomfort or fever. You should stop taking this medicine briefly if any of the following occur: This medicine may cause dizziness and changes in vision. Use caution while driving or performing other tasks requiring alertness, coordination, or physical dexterity. In high oral or parenteral doses, orthostatic hypotension may be encountered at the start of treatment. Treatment with this medicine should be initiated at low doses in patients with arteriosclerosis or cardiovascular problems. This medicine potentiates the action of other phenothiazines and CNS depressants (barbiturates, analgesics, narcotics and antihistaminics). The usual doses of these agents should be reduced by half if they are to be given concomitantly with methotrimeprazine until the dosage of the latter has been established. Because of its anticholinergic effects, methotrimeprazine must be administered with caution in patients with glaucoma or prostatic hypertrophy. During long-term therapy, periodic liver function tests should be performed. In addition, blood counts should be conducted regularly, particularly during the first 2 or 3 months of treatment, and physicians should watch for any signs of blood dyscrasia. Methotrimeprazine does not alter EEG activity. Nevertheless, since phenothiazines can lower the threshold of cortical excitation, it is advisable to administer an appropriate anticonvulsant medication to epileptic patients receiving Nozinan therapy. Patients whose treatment is started by the parenteral route should be kept in bed during the first few days. Be sure to keep appointments. Do not stop taking this medicine without checking with your health care provider. Do not take more medicine than prescribed unless advised to do so by your health care provider. Contact your health care provider at once if you feel like you have taken too much of this medicine. Do not take any other over-the-counter or prescription medications without talking with your health care provider. This includes any herbal preparations or dietary supplements. If a dose is missed, take it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your health care provider. If more than one dose is missed, contact your health care provider or pharmacist.