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Description
Indications
Niacin, in conjunction with a suitable diet and exercise regimen, is employed to aid in the reduction of “bad” cholesterol and fats (LDL, triglycerides) while simultaneously elevating “good” cholesterol (HDL) levels within the bloodstream. Niacin, also recognized as vitamin B-3 (nicotinic acid), belongs to the family of B-complex vitamins. It can be administered alone or in conjunction with other medications. The objective of diminishing “bad” cholesterol and triglycerides and enhancing “good” cholesterol is to lower the risks of stroke and heart attacks. The reduction of fats may also contribute to mitigating the likelihood of pancreas issues (pancreatitis) in individuals predisposed to such concerns.
Uses and Dosage
Administer this medication orally with a low-fat meal or snack, following your doctor’s instructions, usually before bedtime. Consuming niacin on an empty stomach can intensify side effects like flushing and stomach upset. Swallow the tablets whole; do not crush or chew them, as this might lead to a sudden release of the entire dosage, raising the risk of side effects.
Niacin is accessible in various formulations, such as immediate and sustained release. Avoid switching between different strengths, brands, or forms of niacin to avert the possibility of severe liver issues.
The prescribed dosage is contingent upon your medical condition and response to treatment. To mitigate side effects, your doctor may advise commencing with a low dose and gradually increasing it. Even if you are transitioning from another niacin product, the dose should be elevated slowly. Adhere rigorously to your doctor’s directives.
If you are also taking particular other cholesterol-lowering medications like bile acid-binding resins (for example, cholestyramine or colestipol), ingest niacin at least 4-6 hours prior to or after these medications. Such products might interact with niacin, hindering complete absorption. Continue taking other cholesterol-lowering medications as prescribed by your doctor.
To reduce the likelihood of flushing, avoid alcohol, hot beverages, and spicy foods around the time of niacin intake. Consuming an uncoated (non-enteric coated) 325-milligram aspirin or a nonsteroidal anti-inflammatory drug (such as ibuprofen, 200 milligrams) 30 minutes before niacin intake could help prevent flushing. Consult your doctor to determine if this approach suits you.
Maintain regular usage of this medication to attain optimal benefits. Establish a consistent routine by taking it at the same time daily. Even if you feel well, continue using this medication. Many individuals with elevated cholesterol levels might not experience noticeable symptoms.
Do not discontinue this medication without consulting your doctor. Stopping niacin might necessitate reverting to your initial dose and incrementally increasing it once more. Seek guidance from your doctor or pharmacist if you haven’t taken the medication for an extended period (over 7 days) on how to restart your dosage.
Adhering to your doctor’s guidance on diet and exercise remains highly important.
Side Effects
Some side effects may occur that usually do not need medical attention:
- diarrhea
- increased cough
Inform your healthcare provider immediately if you experience any serious side effects:
- dizziness
- faintness
- fast heartbeat
- nausea
- vomiting
- extreme tiredness
- dark colored urine
- light colored stools
- unusual bleeding or bruising
- lack of energy
- loss of appetite
- pain in the upper right part of the stomach
- yellowing of the skin or eyes
- flu-like symptoms
- hives
- rash
- itching
- difficulty breathing or swallowing
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- hoarseness
- unexplained muscle pain, tenderness, or weakness
Caution
Before commencing niacin, inform your doctor or pharmacist if you have any allergic reactions, whether to niacin or other substances. This product might include inert ingredients capable of triggering allergic responses or other complications.
Prior to using this medication, convey your medical history to your doctor or pharmacist, especially if you have a history of very low blood pressure, alcohol consumption, bleeding disorders like low platelet counts, diabetes, gallbladder disease, glaucoma, gout, heart conditions, kidney disease, liver disease or elevated liver enzymes, untreated mineral imbalances, stomach or intestinal ulcers, or hypothyroidism (underactive thyroid).
This medication could induce dizziness. Alcohol or marijuana can amplify this effect. Refrain from activities like driving or operating machinery that demand alertness until you are capable of doing them securely.
In rare instances, this medication might elevate your blood sugar levels, potentially leading to or exacerbating diabetes. If you already have diabetes, diligently monitor your blood sugar as instructed and share the results with your doctor. Alert your doctor immediately if you encounter signs of high blood sugar such as heightened thirst or increased urination. Your doctor might need to modify your diabetes medication, exercise regimen, or diet.
During pregnancy, consider using this medication only when deemed necessary. Engage in a dialogue with your doctor to weigh the potential risks and benefits.
This medication transfers into breast milk. Prior to breastfeeding, consult your doctor.
Form and Strength
Niaspan is available in the following forms and strengths:
-
niacin extended-release tablet:
- 375mg
FAQ
Should I take Niaspan in the morning or at night?
In general, the immediate-release form of niacin should be taken after your evening meal and the extended-release form should be taken at bedtime after a low-fat snack.
How long does it take for Niaspan to lower cholesterol?
Typically, it may take a few weeks for Niaspan to alter cholesterol levels.
Resources
- https://www.goodrx.com/niacin/what-is#faqs
- https://www.medicalnewstoday.com/articles/how-long-does-it-take-for-niacin-to-lower-cholesterol#:~:text=Typically%2C%20it%20may%20take%20a,through%20using%20fats%20and%20proteins
- https://www.medbroadcast.com/drug/getdrug/niaspan
- https://www.webmd.com/drugs/2/drug-4467/niaspan-oral/details
- https://medlineplus.gov/druginfo/meds/a682518.html
- https://www.drugs.com/niaspan.html
