Questran Powder (Cholestyramine)

Description

Indications

Cholestyramine is employed in conjunction with an appropriate dietary regimen to effectively reduce cholesterol levels within the bloodstream. This proactive cholesterol reduction contributes to the mitigation of the risks associated with heart attacks and strokes. Cholestyramine additionally finds application in addressing itching sensations among individuals experiencing an excessive buildup of bile acid due to a specific form of liver or bile duct disorder, known as partial biliary obstruction.

Functioning as a bile acid-binding resin, this medication operates by eliminating bile acid from the body. In individuals afflicted by elevated cholesterol levels, this action stimulates the liver to synthesize more bile acid by utilizing cholesterol present in the bloodstream. This collaborative effort aids in the reduction of cholesterol concentrations.

Uses and Dosage

Consume this medication orally in accordance with your doctor’s instructions, typically once or twice daily. This medication is available as a powder, with doses measured using the provided scoop, or in individual dose packets. Refrain from ingesting the medication in its dry powder state. Instead, blend the prescribed dose with a minimum of 2 to 6 ounces (60 to 180 milliliters) of liquid, such as water, milk, or fruit juice. Thoroughly stir the mixture and promptly drink it. To ensure you’ve ingested the entire dose, rinse your glass with additional liquid and consume the rinsing liquid as well. Alternatively, you can mix the medication with thin soups, applesauce, or pulpy fruits abundant in juice, like crushed pineapple or peaches.

To safeguard your teeth, do not retain the mixture in your mouth for prolonged periods. Uphold good dental hygiene practices, including regular brushing and flossing.

The prescribed dosage hinges on your medical condition and how you respond to the treatment. To minimize the likelihood of side effects, your doctor might initiate the medication at a low dose and gradually escalate it. Follow your doctor’s instructions meticulously. Achieving the full benefits of this drug might necessitate several weeks.

Cholestyramine has the potential to diminish the absorption of other medications. Usually, take your other medications at least 1 hour prior to or 4 to 6 hours after cholestyramine. If you have inquiries or need additional information, consult your doctor or pharmacist.

For optimal results, maintain a consistent regimen of this medication. To facilitate remembrance, consume it at the same time(s) every day. Continuation of this medication is advised even if you feel well; notably, many individuals with elevated cholesterol levels do not experience noticeable symptoms.

Side Effects

Some side effects may occur that usually do not need medical attention:

• heartburn or indigestion
• nausea or vomiting
• stomach pain
• belching
• bloating
• diarrhea
• dizziness
• headache

Inform your healthcare provider immediately if you experience any serious side effects:

• severe stomach/abdominal pain
• unusual bleeding/bruising
• rapid breathing
• confusion
• rash
• itching/swelling (especially of the face/tongue/throat)
• severe dizziness
• trouble breathing

Caution

Before initiating cholestyramine, communicate any existing allergies you have to your doctor or pharmacist, whether related to cholestyramine or other allergens. This product might contain inert components that could elicit allergic reactions or give rise to other complications.

Prior to commencing this medication, provide your medical history to your doctor or pharmacist. This includes specific conditions such as constipation, hemorrhoids, or kidney disease.

Certain formulations of this product may include sugar or aspartame. If you have diabetes, phenylketonuria (PKU), or any other condition mandating the limitation or avoidance of these substances in your diet, it’s prudent to exercise caution.

Given that this medication can potentially hinder the absorption of specific nutrients like folic acid and fat-soluble vitamins A, D, E, and K, your doctor might recommend the inclusion of a multivitamin supplement in your regimen. Seek advice from your doctor for further information.

The elderly population may exhibit heightened sensitivity to the side effects of this medication, particularly constipation.

During pregnancy, the use of this medication should be considered only if it’s deemed essential. This medication could influence the absorption of certain nutrients. Engage in a thorough discussion with your doctor to evaluate the associated risks and benefits.

While it’s improbable that this medication will pass into breast milk, it may still impact the absorption of specific nutrients. Consult your doctor before making a decision about breastfeeding while using cholestyramine.

Form and Strength

Questran Powder is available in the following forms and strengths:

• Questran Powder packet:
  • 4g

FAQ

When is the best time to take Questran Powder?

Take it before a meal or prior to bedtime.

Does Questran Powder stop diarrhea?

Questran Powder is considered to act by abolishing bile acid-induced secretion of water and electrolytes in the colon.

Resources

1. https://www.verywellhealth.com/cholestyramine-overview-1944663#:~:text=Cholestyramine%20is%20most%20effective%20when,instead%20of%20slowly%20sipping%20it
2. https://www.rxlist.com/questran-drug.htm
3. https://www.mayoclinic.org/drugs-supplements/cholestyramine-oral-route/side-effects/drg-20068562?p=1
4. https://www.webmd.com/drugs/2/drug-3334/questran-oral/details
5. https://www.healthlinkbc.ca/medications/cholestyramine-oral
6. https://www.drugs.com/mtm/cholestyramine.html