Biaxin (Clarithromycin)

Description

Indications

Clarithromycin is a macrolide antibiotic that possesses broad-spectrum antibacterial activity, making it useful in the treatment of various bacterial infections. In combination with anti-ulcer medications, this medication is also effective in the management of certain types of stomach ulcers.

Clarithromycin can be used for prophylaxis against specific bacterial infections. Its mechanism of action involves inhibiting bacterial growth. This antibiotic is ineffective against viral infections, such as the common cold or flu. Avoid the unnecessary use of antibiotics, as this can render them ineffective in future infections.

Uses and Dosage

Clarithromycin is available in tablet and suspension forms, as well as an extended-release tablet, intended for oral administration. The conventional tablet and suspension may be ingested with or without food every 8-12 hours, either thrice or twice a day, for 7-14 days. The extended-release tablet should be taken once a day with food, for 7-14 days.

The duration of the treatment may vary depending on the severity of the condition, as advised by your healthcare provider. Take clarithromycin at the same time each day and adhere to the instructions on your prescription label. Refrain from altering the dosage, frequency or duration of treatment without consulting your doctor.

Before using the suspension, ensure that it is thoroughly mixed by shaking it well.

The long-acting tablets should be swallowed whole and should not be crushed, chewed or split.

Symptoms typically improve within the first few days of initiating clarithromycin treatment. If there is no improvement or if the condition worsens, notify your doctor immediately.

Complete the entire course of clarithromycin treatment, even if symptoms improve, to eradicate the infection completely. Abrupt cessation of therapy or missing doses may result in incomplete treatment, allowing the bacteria to develop resistance to antibiotics.

Side Effects

Some side effects may occur that usually do not need medical attention:

• diarrhea
• nausea
• vomiting
• stomach pain
• heartburn
• gas
• change in taste
• headache

Inform your healthcare provider immediately if you experience any serious side effects:

• chest pain, shortness of breath, trouble breathing, pain or weakness in side of your body, or slurred speech
• severe diarrhea with watery or bloody stools (up to 2 months after your treatment)
• rash
• hives
• itching
• swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
• difficulty breathing or swallowing
• hoarseness
• peeling or blistering skin
• fever
• yellowing of the skin or eyes
• extreme tiredness
• unusual bleeding or bruising
• lack of energy
• loss of appetite
• pain in the upper right part of the stomach
• dark-colored urine
• flu-like symptoms
• fast, pounding, or irregular heartbeat
• muscle weakness
• double vision

Caution

Before initiating clarithromycin treatment, notify your healthcare provider or pharmacist of any allergies you have, including hypersensitivity to clarithromycin, other macrolide antibiotics (such as erythromycin, azithromycin), or any other substance. This product may contain inactive components that can trigger allergic reactions or other complications.

Prior to using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of liver disease, kidney disease, heart disease, or a specific type of muscular disease (myasthenia gravis).

Clarithromycin may cause a disturbance in heart rhythm (QT prolongation). In rare cases, this condition can lead to severe symptoms, such as rapid or irregular heartbeat, severe dizziness, and fainting. Immediate medical attention is required if these symptoms arise.

Use of clarithromycin may interfere with the effectiveness of live bacterial vaccines. Inform your healthcare professional about your clarithromycin use before undergoing any immunizations/vaccinations.

Older adults are more prone to experiencing adverse effects from this medication, particularly hearing loss and QT prolongation.

During pregnancy, clarithromycin should only be used if clearly necessary. Consult with your doctor regarding the potential risks and benefits of this medication.

This medication is excreted in breast milk. Prior to breastfeeding, consult your doctor.

Form and Strength

Biaxin is available in the following forms and strengths:

• Biaxin tablet:
  • 250mg
  • 500mg
• clarithromycin tablet:
  • 250mg
  • 500mg

FAQ

How long does it take for Biaxin to start working?

In most cases, it should only take a few days for Biaxin to reduce the symptoms of your infection and make you feel better.

Is Biaxin well tolerated?

Biaxin generally is well tolerated, and side effects usually are mild and transient.

Resources

1. https://www.drugs.com/medical-answers/long-biaxin-work-3562262/#:~:text=In%20most%20cases%2C%20it%20should,and%20symptoms%20to%20go%20away
2. https://www.medicinenet.com/clarithromycin/article.htm
3. https://medlineplus.gov/druginfo/meds/a692005.html
4. https://www.rxlist.com/biaxin-drug.htm
5. https://www.webmd.com/drugs/2/drug-9027-7015/biaxin-oral/clarithromycin-oral/details
6. https://www.mayoclinic.org/drugs-supplements/clarithromycin-oral-route/proper-use/drg-20067672?p=1
7. https://www.drugs.com/biaxin.html