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Buy Estring


(Estradiol Hemihydrate)

Prescription Required
Prescription Required
Paladin Labs
Vaginal Ring
1 Vaginal Ring

What is Estring/Estradiol Hemihydrate used for?

This medicine is used to treat itching, burning, and dryness in or around the vaginal area in women past menopause, for difficult or painful intercourse, and for the treatment of lower urinary tract infection (difficulty urinating or burning during urination).

If you have any questions about your medicine, please talk with your doctor, pharmacist, or health care provider. This medicine is to be taken by the patient in whom it was prescribed. Do not give it to others. This information is advisory only. It does not contain all information about this medicine. If you have any questions about your medicine, ask your doctor, pharmacist, or health care provider.

How should Estring/Estradiol Hemihydrate be stored?

Store at controlled room temperature (59 to 86 degrees F).

General drug information:

General Information

When should Estring/Estradiol Hemihydrate not be taken?

Do not use this medicine if you are allergic to this medicine you are pregnant or suspect you may be pregnant you have abnormal vaginal bleeding of unknown cause you have known or suspected cancer of the breast or the uterus you have cancers that are estrogen-dependent you have a vaginal infection

What precautions should I follow when taking Estring/Estradiol Hemihydrate?

Before using this medicine, tell your health care provider about any of the following: if you are pregnant, plan to become pregnant, or breastfeeding if you are taking any prescription medicine, nonprescription medicine, herbal preparation, or dietary supplement if you have heart disease or high blood pressure if you have diabetes if you have a family history of breast cancer if you have breast lumps, disease, or an abnormal mammogram if you have asthma if you have epilepsy if you have a history of migraine headaches if you have a family history of high cholesterol or high triglyceride levels if you have yellowing of the whites of the eyes or of the skin during pregnancy or during birth control pill use if you have impaired liver or kidney function if you have a vaginal infection or wasting of the vaginal mucous membranes if you have gallbladder disease if you have any other medical conditions

What special warning(s) should I be aware of when taking Estring/Estradiol Hemihydrate?

This medicine may increase the risk of cancer of the uterus in women past menopause. It should not be used during pregnancy due to an increased risk of birth defects in the sex organs of the fetus and possibly other birth defects. Estrogens represent a group of several female hormones. Normally the ovaries produce and release several natural estrogens until menopause occurs. All estrogens produce similar effects. This medicine plays a key role in the development and normal function of the reproductive system (including the vagina, uterus or womb, fallopian tubes and breasts) and secondary sex characteristics (eg, pubic hair) of women. This medicine may also assist in the development and maintenance of strong bones.

What are the side effects of Estring/Estradiol Hemihydrate?

Most severe:  Yellowing of the skin or eyes; heavy vaginal bleeding; pains in calves or chest; sudden shortness of breath; coughing of blood; severe headache or vomiting; dizziness; faintness; changes in vision or speech; weakness or numbness of an arm or

Most common:  Increase of vaginal secretions; vaginal discomfort; abnormal vaginal bleeding; nausea; stomach pain; back, bone, joint, and muscle pain; headache; sleeplessness; upper respiratory tract infection; sinus inflammation; sore throat; urinary tract infection; vaginal infection; flu-like symptoms; hot flashes.

Other:  Breast pain; allergy; anxiety; bronchitis; chest pain; cysts; skin inflammation; diarrhea; indigestion; difficulty urinating; gas; indigestion; vaginal itching; swelling of the legs; migraine headache; ear infection; fainting; toothache; tooth disorder; urge to urinate; dizziness; vomiting; enlarged abdomen; changes in weight; depression; decreased sex drive; nervousness; swelling of the vagina; bleeding between menstrual periods; itching; frequent urination; changes in vision.

How should I take Estring/Estradiol Hemihydrate?

How much medicine you use and how often you use it depends on many factors, including the condition being treated, your age, and weight. If you have any questions about the amount and/or frequency of the medicine you are using, talk with your health care provider. You will need to have a complete medical and family history examination before using this medicine. Wash and dry your hands before removing the ring from the pouch. Use the foil pouch to dispose of the ring after use. To insert the ring, choose a comfortable position, such as lying down, squatting, or standing with one leg up. Hold the ring between your thumb and index finger and press the opposite sides of the ring together. Gently push the folded ring into your vagina. The exact position of the ring in the vagina is not important for it to work. You may not feel the ring once it is in place. If you feel discomfort, the ring is probably not inserted back far enough in your vagina. Use your finger to gently push the ring further into your vagina. There is no danger in the ring being pushed too far up in the vagina or getting lost. It can be inserted only as far as the end of the vagina. The cervix will block it from going any further. Once inserted, keep the ring in place for 90 days. After the ring is removed, it may be replaced by a new ring if treatment is still necessary. To remove the ring, wash and dry your hands thoroughly. Find a comfortable position, either standing, squatting, or lying down. Loop your finger through the ring and gently pull it out. Throw away the used ring. Some women have experienced moving or gliding of the ring within the vagina due to bowel movements, strains, or constipation. If this occurs, the ring can be rinsed in lukewarm (not hot) water and reinserted into the vagina. If the ring is removed or falls out during the 90-day treatment period, rinse the ring with lukewarm water and reinsert it. Women taking this medicine should examine their breasts regularly. Contact your health care provider immediately if vaginal bleeding of unknown cause occurs. This could be a sign of a serious symptom requiring immediate medical attention. Contact your doctor at once if any of the following occurs: Abnormal vaginal bleeding; calf or chest pain; sudden shortness of breath; coughing blood; severe headaches; dizziness; faintness; changes in vision or speech; weakness or numbness of an arm or leg; breast lumps; yellowing of the skin or eyes; pain, swelling or tenderness of the stomach. Contact your doctor if vaginal discomfort occurs or if you suspect you have developed a vaginal infection while using this medicine. This medicine may cause dizziness. Use caution while driving or performing other tasks requiring alertness, coordination, or physical dexterity. Lab tests will be required to monitor therapy. You will need to have follow-up exams at least once a year. Be sure to keep appointments. Do not stop using this medicine without checking with your doctor. Do not use more medicine than prescribed unless advised to do so by your doctor or health care provider. If a dose is missed, use it as soon as possible. If several hours have passed or if it is nearing time for the next dose, do not double the dose to catch up, unless advised by your doctor. If more than one dose is missed, contact your doctor or pharmacist.