Restasis (Cyclosporine)

Description

Indications

Ophthalmic cyclosporine is employed to enhance tear production in individuals experiencing dry eye disease. Classified as an immunomodulator, cyclosporine functions by reducing eye inflammation, thereby facilitating tear production.

Uses and Dosage

Ophthalmic cyclosporine is available in two forms: a solution (liquid) and an emulsion (a mixture of two unblendable liquids) for eye instillation. It is typically administered twice daily, with a 12-hour interval between each application.

To ensure consistent dosage, instill the eye drops at approximately the same times daily. Use cyclosporine eye drops precisely as directed, neither exceeding nor reducing the recommended amount or frequency.

Remember that cyclosporine eye drops are exclusively for ocular use and must not be ingested or applied to the skin.

Cyclosporine eye drops are available in single-dose vials and multi-dose bottles. When using single-dose vials, use the entire contents for one or both eyes immediately after opening.

Avoid letting the dropper tip touch your eye, face, fingers, or any surface, as this may introduce bacteria into the eye drops.

To administer the eye drops, the following steps should be followed:

1. Thoroughly wash hands with soap and water.
2. Do not allow the dropper tip to touch the eye or any other surface, and ensure that it is kept clean.
3. Tilt the head back and pull down the lower lid of the eye using the index finger to form a pocket.
4. Hold the dropper as close to the eye as possible without making contact, and brace the remaining fingers against the face.
5. Squeeze the dropper gently to instill a single drop in the pocket created by the lower eyelid while looking upwards.
6. Remove the index finger from the lower eyelid and keep the eye closed for 2-3 minutes while tilting the head down.
7. Apply gentle pressure to the tear duct using a finger.
8. Use a tissue to wipe off any excess liquid from the face.
9. Wash hands to remove any residual medication.

Side Effects

Some side effects may occur that usually do not need medical attention:

• burning, itching, stinging, redness, or pain of the eyes
• eyelid swelling
• eye discharge
• blurred vision or other vision changes
• feeling that something is in the eye
• headache

Inform your healthcare provider immediately if you experience any serious side effects:

• hives
• itching
• face, throat, eyes, and tongue swelling
• shortness of breath

Caution

Prior to using this medication, notify your pharmacist or physician if you have any allergies, including an allergy to this medication or other substances. Inactive constituents in the product can cause allergic reactions or other adverse effects.

Inform your pharmacist or doctor about your medical history, particularly if you have had a recent/current eye infection.

Following application of this medication, your vision may be temporarily impaired. Refrain from driving, operating machinery, or performing any activity that necessitates clear vision until it is safe to do so.

During pregnancy, use this medication only if it is absolutely necessary, after discussing the potential risks and benefits with your doctor.

It is uncertain if this medication is excreted in breast milk. Prior to breastfeeding, seek advice from your doctor.

Form and Strength

Restasis is available in the following forms and strengths:

• Restasis eye drops:
  • 0.05%
• cyclosporine eye drops:
  • 0.05%

FAQ

What should you expect when you take Restasis?

When using Restasis, you might experience temporary burning or stinging. This may be a response to treatment and is the most common side effect.

How long can you safely use Restasis?

Patients are advised to use Restasis for a minimum of 6 months, with the understanding that the vast majority will require lifelong treatment to remain symptom-free.

Resources

1. https://www.restasis.com/about-restasis/efficacy-and-safety#:~:text=When%20using%20RESTASIS%C2%AE%2C%20you,%2C%20stinging%2C%20and%20blurred%20vision
2. https://www.drugs.com/medical-answers/restasis-safe-long-term-3566632/#:~:text=In%20general%2C%20patients%20are%20advised,treatment%20to%20remain%20symptom%2Dfree
3. https://www.medbroadcast.com/drug/getdrug/restasis
4. https://www.webmd.com/drugs/2/drug-74924/restasis-ophthalmic-eye/details
5. https://medlineplus.gov/druginfo/meds/a604009.html
6. https://www.drugs.com/restasis.html