Description
Indications
Tolterodine is indicated for the management of overactive bladder, a medical condition characterized by involuntary and excessive contractions of the bladder muscles, resulting in symptoms such as frequent urination, urgent urination, and urinary incontinence. This medication belongs to the class of antimuscarinics, and its mechanism of action involves the relaxation of the bladder muscles to inhibit bladder contractions.
Uses and Dosage
Take this medication orally, with or without food, as directed. Typically, it is taken once a day.
Swallow the medication whole with a full glass of liquid. Do not crush or chew the medication, as doing so may compromise its extended-release formulation and potentially lead to an increase in adverse effects.
Consistency in medication usage is crucial to derive optimal benefits. To aid in remembering, try to take it at the same time each day. The prescribed dosage is determined based on your specific medical condition, taking into account factors such as kidney and liver function, response to treatment, and concurrent use of other medications.
Do not exceed the recommended dosage or take this medication more frequently than instructed. Increasing the dosage or frequency will not accelerate improvement in your condition and may heighten the risk of experiencing severe side effects.
If your condition persists or worsens, inform your doctor promptly.
Side Effects
Some side effects may occur that usually do not need medical attention:
- dry mouth
- heartburn
- headache
- constipation
- diarrhea
- dry eyes
- dry skin
- joint pain
- abdominal pain
- excessive tiredness
- difficulty emptying the bladder
- painful urination
- weight gain
- anxiety
Inform your healthcare provider immediately if you experience any serious side effects:
- swelling of the face, throat, tongue, lips, and eyes
- difficulty swallowing or breathing
Caution
Prior to initiating tolterodine treatment, disclose any known allergies to this medication, fesoterodine, or other substances, to your doctor or pharmacist. Inactive ingredients present in the product may also trigger allergic reactions or other complications.
Before commencing the use of this medication, inform your healthcare provider about your medical history, particularly if you have experienced difficulties with bladder emptying, severe stomach or intestinal blockage, glaucoma, stomach or intestinal disorders, severe constipation, kidney disease, liver disease, or a specific muscle condition known as myasthenia gravis.
Tolterodine has the potential to cause an irregularity in heart rhythm called QT prolongation. While this is a rare occurrence, it can lead to serious consequences. Symptoms such as severe dizziness, fainting, or other related signs should be addressed promptly.
The risk of QT prolongation may be elevated if you have low levels of potassium or magnesium in your blood. Certain medications (such as diuretics or “water pills”) or specific conditions like excessive sweating, diarrhea, or vomiting can further increase this risk.
Elderly individuals may be more susceptible to the side effects of this medication, including QT prolongation, drowsiness, confusion, constipation, or difficulties with urination. Drowsiness and confusion can heighten the risk of falls.
Tolterodine may induce dizziness, drowsiness, or blurred vision. Consuming alcohol or marijuana can intensify these effects. Refrain from driving, operating machinery, or engaging in activities that require alertness or clear vision until you can do so safely.
This medication may reduce sweating, potentially increasing the likelihood of heat stroke. Avoid situations that may cause overheating, such as strenuous work or exercise in hot weather, and using hot tubs. When the weather is hot, stay hydrated by consuming ample fluids and dress lightly. If you experience overheating, promptly seek a cool environment and rest. Seek immediate medical assistance if you have an ongoing fever, experience changes in mental state, develop a headache, or feel dizzy.
During pregnancy, the use of this medication should only be considered when clearly necessary. Discuss the potential risks and benefits with your doctor.
It is unknown whether this drug passes into breast milk. Prior to breastfeeding, consult your doctor for guidance.
Form and Strength
Detrol LA is available in the following forms and strengths:
-
Detrol LA capsule:
- 2mg
- 4mg
-
tolterodine LA capsule:
- 2mg
- 4mg
FAQ
How long does Detrol take to work?
According to a small study, it could take up to 7 days for the immediate-release version of Detrol to start relieving symptoms. In a different study, the extended-release version started to work as soon as 5 days after starting treatment.
Should I avoid drinking water while I’m taking Detrol?
No, avoiding water can actually make your OAB symptoms worse and make you dehydrated. It’s important to stay hydrated and find the right balance of water to drink.