Pioglitazone is utilized in combination with a proper diet and exercise routine, and sometimes with other medications, to treat type 2 diabetes, a condition in which the body is unable to utilize insulin effectively and consequently cannot regulate the glucose levels in the bloodstream. Pioglitazone belongs to the class of medicines known as thiazolidinediones, which function by boosting the body’s insulin sensitivity, a natural substance that aids in regulating blood sugar levels.
This medication is not used to treat type 1 diabetes, a condition in which the body does not generate insulin and hence is incapable of controlling the amount of sugar in the bloodstream, or diabetic ketoacidosis, a severe condition that may develop when high blood sugar levels are not treated.
Uses and Dosage
Administer this medication orally, with or without food, according to the instructions of your physician, generally once daily. The dosage is dependent on your medical condition, response to treatment, and whether you are taking other diabetes medications. Your physician will alter your dose based on your blood sugar levels to determine the optimal dosage for you. Follow your physician’s instructions precisely.
To obtain the most benefit from this medication, consume it on a regular basis. Remember to take it at the same time each day.
If you are already taking another diabetes medication, such as metformin or a sulfonylurea, closely adhere to your physician’s instructions on discontinuing or continuing the old medication and commencing this medication. Adhere closely to the medication treatment plan, meal plan, and exercise program recommended by your physician.
Check your blood sugar levels as directed by your physician and keep track of the findings, sharing them with your physician. Inform your physician if your blood sugar measurements are excessively high or low, as your dosage or treatment may require modification.
It may take up to 2 to 3 months for the full advantages of this medication to take effect.
Some side effects may occur that usually do not need medical attention:
- blurred vision or other changes in vision
- dry mouth
- flushed, dry skin
- fruit-like breath odor
- increased hunger
- increased thirst
- increased urination
- loss of consciousness
- muscle pain or soreness
- problems with your teeth
- runny or stuffy nose
- sore throat
- unexplained weight loss
Inform your healthcare provider immediately if you experience any serious side effects:
- chest pain
- decreased urine output
- dilated neck veins
- extreme fatigue
- irregular breathing
- irregular heartbeat
- problems with teeth
- swelling of the face, fingers, feet, or lower legs
- tightness in the chest
- trouble breathing
- weight gain
- Less common
- Pain or swelling in the arms or legs without an injury
- pale skin
- trouble with breathing when active
- unusual bleeding or bruising
- unusual tiredness or weakness
Prior to taking pioglitazone, inform your healthcare provider or pharmacist if you have an allergy to this medication or if you have any other allergies. This product may contain inactive ingredients that can cause allergic reactions or other complications.
Prior to using this medication, inform your healthcare provider or pharmacist of your medical history, especially if you have a heart condition (such as chest pain or congestive heart failure), liver disease, fluid in your lungs, swelling (edema), anemia, a specific eye problem (macular edema), or bladder cancer.
You may experience blurred vision, dizziness, or drowsiness due to extremely low or high blood sugar. Refrain from driving, operating machinery, or engaging in activities that require alertness or clear vision until you are confident that you can carry out these activities safely.
It may be more challenging to manage your blood sugar when your body is under stress. Consult your healthcare provider because increased stress may necessitate a change in your treatment plan, medications, or blood sugar testing.
Pioglitazone may increase the risk of bone fractures in women.
Pioglitazone can cause changes in the menstrual cycle (promote ovulation) and increase the risk of pregnancy. Consult your healthcare provider or pharmacist about the use of reliable birth control while using this medication.
During pregnancy, this medication should only be used when clearly needed. Discuss the risks and benefits with your doctor. Your doctor may replace this medication with insulin during your pregnancy.
It is not known if this medication passes into breast milk. Consult your healthcare provider before breastfeeding.
Form and Strength
Actos is available in the following forms and strengths:
Does everyone gain weight on Actos?
Weight gain is a possible side effect of Actos.
How fast does Actos lower blood sugar?
It may take several weeks to lower your blood sugar and 2 to 3 months for you to see the full effect of Actos.