What is Agrylin used for
Agrylin is the first-line anti-platelet medication. Its generic name is anagrelide. This medication helps treat thrombocythemia (excessive platelet production) caused by myeloproliferative disease.
Anagrelide can be used as single-agent therapy or in conjunction with other medications. This drug can be used for children aged seven and up.
How does Agrylin work?
Platelets are tiny blood cells produced in the bone marrow by a particular cell called megakaryocytes. It is an essential component of the blood that aids your body from clots to stopping bleeding.
Thrombocythemia occurs due to certain illnesses, and too many platelets in the body can be dangerous. This phenomenon can cause blood clots in the blood vessels, nose bleeds, unexplained bruising, bloody stools, weakness, and excessive bleeding, among others side effects.
When Agrylin is administered correctly and absorbed into the bloodstream, it limits the number of platelets by suppressing GATA-1 and FOG-1, required for megakaryocytopoiesis. As a result, it decreases the number of platelets in the bloodstream, relieving thrombocythemia problems.
Dosage of Agrylin
The dosage and frequency of using anagrelide differ from person to person. It usually depends on the severity of your condition, age, and tolerance to treatment. This oral medication is available in Agrylin 0.5 mg per capsule.
The recommended adult dose is 0.5 mg taken four times a day or 1 mg twice daily. The suggested starting dose for pediatric patients is 0.5 mg once a day. The dosage can be modified depending on your response to the treatment and evaluation of your doctor.
Best way to use Agrylin
When using this prescription drug, make sure to read all drug information and guidelines thoroughly. As much as possible, follow all the directions. If you are unsure how to use this drug, talk to your doctor or pharmacist for clarification.
As prescribed, administer this drug orally two or four times a day. You may take anagrelide with or without regard to food. Be sure to swallow the capsule whole; do not chew or crush it.
It is best to take this drug regularly at the same time every day. You may opt to put a marking in your calendar or set a daily reminder to avoid forgetting a pill. If you missed a dose, call your doctor immediately for instructions.
Agrylin side effects
The most commonly reported side effects of using this medication that usually improves over time are as follows:
- Abnormal heart rate
- Shortness of breath
- Loss of appetite
There are quite a few cases where these effects worsen. Immediately contact your doctor if you suffer any of the following adverse effects:
- Chest pain
- Unusual bleeding or bruising
- Black stools
- Changes in the amount and color of the urine
- Coffee ground like vomitus
- Severe dizziness
- Trouble speaking
- Vision changes
Keep in mind that this is not a comprehensive list of the potential health implications related to this med. This Agrylin prescribing information is for educational purposes only.
Before beginning this therapy, fully disclose your medical history to your doctor, especially if you have heart, kidney, liver, or respiratory problems. Doing so will help your physician decide if this medication is appropriate for you.
Avoid using this drug if you are allergic to anagrelide or any other component. When taking this anti-platelet medication, keep an eye out for any allergic reactions such as rashes, hives, swelling of the face and lips, throat tightness, or difficulty breathing. As soon as these signs and symptoms appear, you should seek medical help immediately.
Do not use this medication if you have congenital QT syndrome, have had a history of QT prolongation, and have hypokalemia, as this can exacerbate your condition.
Monitor your ECG (EKG) and other laboratory tests regularly to avoid heart rhythm abnormalities while taking this drug.
Avoid activities requiring alertness (driving or operating machines), as this drug can cause dizziness and prevent unwanted accidents.
Inform your primary care provider about your medicines and supplements, especially if you are on aspirin, to avoid drug interactions.
How much does Agrylin cost?
Agrylin is the first treatment of choice for thrombocythemia. The price is a little high due to the drug’s effectiveness. If your doctor permits, you may purchase this medication in its generic version for a lower price.
Frequently asked questions
Does Agrylin work as an anticoagulant?
No. Agrylin medication is an anti-platelet agent that decreases the number of platelets in the body.
Does Agrylin cause bleeding?
Yes. Anagrelide medication can make you bleed and bruise easily. Do not indulge in contact sports or any activity that could result in cuts, bleeding, or bruising.
Is Agrylin safe for pregnant women?
Before starting Agrylin treatment, weigh its benefits and risks. Make sure to consult your doctor first to prevent harming your unborn child.