Prescription Required 
Formulation : 
Description
Indications
Risedronate tablets and delayed-release (long-acting tablets), are employed for the prevention and treatment of osteoporosis. This medication is also utilized in the treatment of osteoporosis in both men and women who are undergoing glucocorticoid therapy and for the treatment of Paget’s disease of bone. Risedronate belongs to a class of medications known as bisphosphonates, operating by inhibiting bone breakdown and enhancing bone density (thickness).
Uses and Dosage
Administer this medication orally with or immediately following breakfast, as prescribed by your doctor, typically once a week. Select a consistent day of the week that aligns with your schedule, taking it on the same day each week. Avoid taking it at bedtime or while still in bed.
Consume this medication with at least half a glass (4 ounces/120 milliliters) of plain water, refraining from any other beverages. Swallow the tablet whole; do not cut, crush, chew, or suck on it. After ingestion, maintain an upright position (sitting, standing, or walking) and refrain from lying down for at least 30 minutes.
Calcium or iron supplements, mineral-containing vitamins, and products containing calcium/magnesium/aluminum (e.g., antacids, laxatives) may interfere with the absorption of risedronate. Similarly, medications such as quinapril, specific formulations of didanosine (chewable/dispersible buffered tablets or pediatric oral solution), sucralfate, and bismuth subsalicylate may also disrupt absorption. Administer these products at different times of the day from when you take risedronate. Wait at least 30 minutes after taking risedronate before consuming these other products.
Consistently adhere to the medication schedule to maximize its benefits. Remember to take it on the same day each week; marking your calendar with a reminder may be helpful.
Discuss with your doctor the potential risks and benefits associated with long-term use of this medication.
Side Effects
Some side effects may occur that usually do not need medical attention:
- nausea
- burping
- dry mouth
- stomach pain
- diarrhea
- constipation
- gas
- headache
- dizziness
- weakness
- leg cramps
- back pain
- frequent or urgent need to urinate
Inform your healthcare provider immediately if you experience any serious side effects:
- difficulty swallowing or pain when swallowing
- new or worsening heartburn
- chest pain
- itching
- rash
- hives
- blisters on skin
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- difficulty breathing
- hoarseness
- muscle spasms, twitching, or cramps
- numbness or tingling around mouth or in hands or feet
- swollen, red, or painful eyes
- sensitivity to light
- painful or swollen gums
- loosening of the teeth
- numbness or heavy feeling in the jaw
- poor healing of the jaw
- dull, aching pain in the hips, groin, or thighs
Caution
- Prior to taking risedronate, inform your doctor or pharmacist about any allergies you may have, as this product could contain inactive ingredients that may lead to allergic reactions or other complications.
- Before initiating this medication, disclose your medical history to your doctor or pharmacist, especially if you have kidney disease, difficulty sitting upright or standing for 30 minutes, low levels of calcium in the blood (hypocalcemia), esophageal disorders, painful or challenging swallowing, or stomach/intestinal disorders.
- Some individuals taking risedronate may experience serious jawbone problems. Your doctor should examine your mouth before starting this medication. Inform your dentist about taking this medication before any dental procedures. To reduce the risk of jawbone problems, undergo regular dental check-ups and adopt practices for maintaining oral health. If you experience jaw pain, promptly inform your doctor and dentist.
- Notify your doctor if you are pregnant or planning to become pregnant, as risedronate may persist in your body for an extended period. You should not become pregnant while using risedronate, and you should discuss the associated risks and benefits with your doctor.
- The passage of this medication into breast milk is unknown. Consult your doctor before breastfeeding.
Form and Strength
Atelvia DR is available in the following forms and strengths:
- Atelvia DR tablet:
- 35 mg
FAQ
How long does Atelvia DR take to work?
For osteoporosis, Atelvia DR usually starts to work after 2 weeks. However, it may take 6 months for the medicine to fully protect your bones. When used for Paget’s disease of bone, Atelvia DR reduces bone pain, but it may take 3 to 6 months for your symptoms to improve.
Can I drink alcohol while taking Atelvia DR?
Yes, you can drink alcohol while taking Atelvia DR. However, drinking a lot of alcohol affects the strength of your bones and can increase your risk of breaks (fractures).
Resources
- https://www.nhs.uk/medicines/risedronate/common-questions-about-risedronate/
- https://www.mayoclinic.org/drugs-supplements/risedronate-oral-route/description/drg-20067115
- https://www.webmd.com/drugs/2/drug-154925/atelvia-oral/details
- https://medlineplus.gov/druginfo/meds/a601247.html
- https://www.drugs.com/atelvia.html
