Agrylin medication is used to treat Essential Thrombocythemia. Agrylin works by using the active drug anagrelide to reduce the number of platelets being produced in the bone marrow. Anagrelide is a first-line medication that belongs to a class of drugs known as Antiplatelet agents.
What is Essential Thrombocythemia?
Essential Thrombocythemia is a disease that affects the production of platelet cells. Platelets are produced by cells called megakaryocytes found in the bone marrow. Our bodies need platelets to help us form thick blood clots that can stop bleeding.
Although platelets are essential components of blood, they can become dangerous when the body produces too many of them. Thrombocythemia can cause blood clots in arteries and veins, nose bleeds, unexplained bruising, bloody stools, weakness, excessive bleeding, and swollen lymph nodes.
The cause of Essential Thrombocythemia isn’t known. Although there is no known cure for thrombocythemia, Agrylin has shown to be effective at negating the symptoms and controlling the disorder by reducing platelet over-production.
Side Effects of Agrylin
The side effects of this medication can be serious in some cases, including heart attack, heart failure, pancreatitis, and other blood or heart-related conditions. You should notify your doctor right away if you experience any of the following side effects:
- Chest pain
- Loss of consciousness
- Heart palpitations
- Pounding heartbeat
- Swelling in the feet or ankles
- Trouble Breathing
- Excessive bleeding
- Blood clots
- Blood in your stool
- Swelling, pain, and redness in extremities
- Difficulty swallowing
- Pneumonia or bronchitis
- Decreased sensations
- Memory loss
- High or low blood pressure
- Vision changes
- Urinary problems
- Severe coughing
- Kidney problems (nausea, vomiting, urinary retention, fatigue)
- Symptoms of liver disease (nausea, vomiting, loss of appetite, dark urine, jaundice)
- Allergic reaction (Swelling of the face, tongue, or throat, skin rashes, difficulty breathing)
Other side effects can be less dangerous, including:
- Stomach pain
- Eye infection or irritation
If you experience less serious side effects, you should talk to your doctor if they are severe or if they don’t go away after a couple of days. If you experience multiple side effects, it may be an indication that a more serious condition has developed, and you should talk to your doctor without hesitation.
It’s most common to start the treatment with one Agrylin 0.5 mg tablet daily, before increasing the dosage gradually to a target of 1 mg daily (four 0.5 mg tablets taken throughout the day). It’s recommended that a lower dose be given to those with a medical history involving hepatic impairment or heart conditions. Tell your doctor your full medical history before taking this medication, especially of bleeding problems, long QT syndrome, heart problems, liver disease, and electrolyte imbalances.
You should take Agrylin exactly as prescribed to you by your doctor. Do not take more than they have advised you to take, and never exceed a dose of 10 mg per day. If you miss your dose, simply skip the missed dose and refrain from double dosing to avoid overdose. Keep Agrylin stored at room temperature, away from the reach of young children or pets.
The price of Agrylin is often high. To help with the cost, a generic version of the drug is available under the name Anagrelide. Purchasing Agrylin generic from a Canadian mail-order pharmacy can help you save up to $700 for a supply of 100 tablets.