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Formulation : 
Description
Indications
Bactrim, a combination medicine that contains the antibiotics sulfamethoxazole and trimethoprim, is employed for the treatment of a broad spectrum of bacterial infections, such as otitis media, urinary tract, respiratory tract, and gastrointestinal tract infections. Bactrim can also be utilized for the management of pneumocystis pneumonia.
Note that the use of this medication is contraindicated in children under 2 months of age, owing to the potential for serious adverse effects.
Bactrim is effective only against specific types of infections, and is ineffective against viral infections such as the influenza virus. Overutilization or inappropriate use of antibiotics may result in a decline in their efficacy.
Uses and Dosage
Bactrim is to be administered orally, as instructed by your physician, along with a full glass of water (8 ounces/240 milliliters). In case of digestive discomfort, take the medication with food or milk. Consume adequate fluids while on this medication to minimize the potential risk of renal stone formation, unless advised otherwise by your doctor. The dosage is based on your medical status and response to therapy.
For optimal efficacy, this antibiotic should be taken at regular intervals. To aid in recall, it is advisable to consume the medication at the same time(s) every day.
Complete the entire prescribed course of this medication, even if your symptoms subside after a few days, as premature cessation of therapy may result in bacterial proliferation, leading to a recurrence of the infection.
If your condition persists or worsens, inform your physician immediately.
Side Effects
Common adverse effects associated with Bactrim may include:
- nausea
- vomiting
- loss of appetite
Inform your healthcare provider immediately if you experience any serious side effects while taking Bactrim, including:
- rash
- itching
- sore throat
- fever or chills
- severe diarrhea (watery or bloody stools) that may occur with or without fever and stomach cramps (may occur up to 2 months or more after yourtreatment)
- shortness of breath
- cough
- unusual bruising or bleeding
- yellowing of the skin or eyes
- paleness
- red or purple skin discolorations
- joint or muscle pain
Caution
Prior to beginning Bactrim treatment, inform your physician or pharmacist of any sulfa medication or trimethoprim allergies or any other allergies. The medication may contain inactive components that may cause allergic reactions or other adverse events.
Inform your healthcare provider of your use of this medication prior to receiving any immunizations/vaccinations, as it may affect the efficacy of live bacterial vaccines (such as typhoid vaccine).
Bactrim may increase your sensitivity to the sun. Minimize exposure to sunlight, avoid tanning beds and sun lamps, and use sunscreen and protective clothing when spending time outdoors. Seek medical attention if you experience sunburn or skin blisters/redness.
In case of diabetes, this medication may impact blood sugar levels. Regular monitoring of blood sugar levels as directed, and sharing the results with your physician, is recommended. If you experience symptoms of low blood sugar, seek medical attention immediately. Your physician may need to make adjustments to your diabetes management, exercise regimen, or diet.
Individuals with AIDS may be more prone to the adverse effects of this drug, particularly skin reactions, fever, and hematological disorders.
Inform your physician if you are pregnant or plan to conceive. You should avoid pregnancy while on sulfamethoxazole/trimethoprim therapy, as the medication may cause harm to the developing fetus. If you become pregnant, seek medical advice promptly to weigh the potential risks and benefits of this medication. Sulfamethoxazole/trimethoprim is excreted into breast milk, although there have been no reports of harm to healthy infants.
Consult your physician before starting breastfeeding.
Form and Strength
Bactrim is available in the following forms and strengths:
-
sulfamethoxazole-trimethoprim tablet:
- 400/80mg
FAQ
How long does it take to feel better after taking Bactrim DS?
Bactrim is absorbed by the body and begins to kill bacteria within 1 to 4 hours after taking your dose. For more common problems like urinary tract infections and ear infections, most people will start to feel relief after a few days.
Do most people tolerate Bactrim DS?
Although this drug is well tolerated by many patients, it is associated with several potentially serious adverse reactions.
Resources
- https://www.goodrx.com/sulfamethoxazole-trimethoprim/what-is
- https://medlineplus.gov/druginfo/meds/a684026.html
- https://www.webmd.com/drugs/2/drug-5530/bactrim-ds-oral/details
- https://www.drugs.com/bactrim.html
- https://www.mayoclinic.org/drugs-supplements/sulfamethoxazole-and-trimethoprim-oral-route/side-effects/drg-20071899?p=1
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216436/
