Prescription Required 
Formulation : 
Description
Indications
The combination of sodium picosulfate, magnesium oxide, and anhydrous citric acid is indicated for use in adults and children aged 9 years and above to facilitate the emptying of the colon prior to a colonoscopy.
Sodium picosulfate belongs to the class of drugs known as stimulant laxatives, while magnesium oxide and anhydrous citric acid combine to form magnesium citrate, which belongs to the class of drugs known as osmotic laxatives. These drugs exert their effects by inducing watery diarrhea to clear out stool from the colon. This enables the physician to obtain a clear view of the colon walls during the colonoscopy procedure.
Uses and Dosage
Adhere to any dietary instructions provided by your physician. Typically, only clear liquids are allowed the day prior to your procedure. Avoid consuming milk, dairy products, red or dark-colored liquids, and alcohol. To prevent dehydration, consume as much clear liquid as possible before, during, and after taking the medication. Follow your doctor’s advice on which types of clear liquids to consume.
Administer this product in two separate doses, following your physician’s guidance on when to take each dose. The dose prescribed will be based on your medical condition and age.
This product is available in either a powder form that needs to be mixed with water or a pre-mixed liquid in bottles. Carefully follow the instructions provided for your specific product. If you are using the powder packets, mix each dose with 5 ounces/150 milliliters of cold water, stirring well until the powder is completely dissolved (usually 2 to 3 minutes). Drink the entire mixture.
In the event of bloating or stomach/abdominal pain after taking the product, taking a break from consuming clear liquids or waiting a longer period between each dose may be helpful.
Watery bowel movements typically commence 2 to 4 hours after ingesting the medication, indicating that it is working as intended. Ensure that you have access to a toilet until the medication’s effects have worn off.
Do not take any oral medication one hour before consuming this product, as it may impact the absorption of the medication. Certain medications, such as digoxin, iron, tetracycline antibiotics, quinolone antibiotics like ciprofloxacin/levofloxacin, chlorpromazine, and penicillamine, should not be taken 2 hours before or 6 hours after ingesting this product.
Side Effects
Some side effects may occur that usually do not need medical attention:
- nausea
- stomach pain, cramps, or fullness
- bloating
- headache
Inform your healthcare provider immediately if you experience any serious side effects:
- vomiting, especially if you can’t keep down the fluids that you need for your treatment
- dizziness
- fainting
- shakiness, sweating, hunger, moodiness, or anxiety, especially in children
- changes in heart rate and blood pressure that may happen up to 7 days after the procedure
- deceased urination
- stool that is bloody or black and tarry
- bleeding from rectum
- seizures
- irregular heartbeat
- rash
- hives
Caution
Prior to taking this medication, inform your healthcare provider or pharmacist if you have any known allergies. This product may include inactive ingredients that can cause allergic reactions or other complications.
Before commencing the use of this medication, discuss your medical history with your healthcare provider or pharmacist, particularly if you have a history of heart problems, kidney problems, salt/mineral imbalance (such as low levels of sodium in the blood), seizures, stomach/intestinal problems (e.g. gastric retention, blockage, ulcers, ulcerative colitis), or difficulty swallowing.
When pregnant, this medication should only be used when absolutely necessary. Discuss the potential risks and benefits with your healthcare provider.
It is uncertain whether this product passes into breast milk. Consult with your healthcare provider before breastfeeding.
Form and Strength
Clenpiq is available in the following forms and strengths:
-
Clenpiq powder for solution:
- 10mg
- 3.5g
- 12g
FAQ
How long does it take to clear bowels with Clenpiq?
Some people will begin to have multiple urgent bowel movements within 30 minutes of drinking the solution and others may not have a bowel movement for 5-6 hours.
How can I make Clenpiq work better?
Drink at least five (5) 8 oz. cups of clear liquids, taken at your own pace before going to bed. This will help the medicine to clean your bowels.
Resources
- https://www.mygenesishealth.com/treatment-options/genesis-gastroenterology/Coastal-GI-Directions-Clenpiq.pdf
- https://my.clevelandclinic.org/health/articles/21218-clenpiq-bowel-preparation-instructions
- https://www.webmd.com/drugs/2/drug-174540/clenpiq-oral/details
- https://medlineplus.gov/druginfo/meds/a613020.html
- https://www.drugs.com/mtm/clenpiq.html
