Prescription Required 
Formulation : 
Description
Indications
Galantamine is prescribed for alleviating the symptoms of Alzheimer’s disease (AD), a progressive neurological disorder that gradually diminishes memory, cognitive functions, communication skills, and the capacity to manage daily tasks. Categorized as an acetylcholinesterase inhibitor, galantamine operates by augmenting the levels of a specific natural compound within the brain crucial for memory and cognitive processes.
Uses and Dosage
Administer this medication orally alongside a meal, following the guidance of your doctor. Typically, take it twice daily during your morning and evening meals. While using this medication, ensure sufficient fluid intake unless otherwise directed.
To mitigate potential side effects, your dose will be progressively adjusted to reach the target dosage. Your specific dosage hinges on your medical condition and your response to the treatment.
In case you’re utilizing the liquid variant of this medication, carefully peruse the instruction sheet provided by the manufacturer within the bottle. Adhere to the directions meticulously. Utilize the measuring device accompanying the product to measure your dose accurately. Blend your prescribed dose with roughly 4 ounces (120 milliliters) of a nonalcoholic beverage, stir thoroughly, and consume the entire mixture.
Should you cease taking galantamine for a period exceeding 3 days, your doctor may instruct you to recommence the medication at a low dosage and gradually escalate it. This approach helps mitigate the risk of potential side effects. Adhere closely to your doctor’s directives.
To derive the most benefits from this medication, ensure regular usage. Do not discontinue usage or adjust the dosage without explicit instructions from your doctor.
Be prepared for a minimum of 4 weeks of continuous use before observing the complete effects of this medication. Should your condition worsen, promptly inform your doctor.
Side Effects
Some side effects may occur that usually do not need medical attention:
- nausea
- vomiting
- diarrhea
- loss of appetite
- stomach pain
- heartburn
- weight loss
- extreme tiredness
- dizziness
- pale skin
- headache
- shaking of a part of your body that you cannot control
- depression
- difficulty falling asleep or staying asleep
- runny nose
Inform your healthcare provider immediately if you experience any serious side effects:
- difficulty urinating
- blood in the urine
- pain or burning while urinating
- seizures
- slowed heartbeat
- fainting
- shortness of breath
- black and tarry stools
- red blood in the stools
- bloody vomit
- vomit that looks like coffee grounds
Caution
Prior to initiating galantamine, inform your healthcare provider or pharmacist about any allergies you may have, whether to galantamine itself, daffodil plants, or any other allergens. This medication might contain inactive components capable of inducing allergic reactions or other adverse effects.
Before commencing this medication, share your medical history with your doctor or pharmacist, particularly any instances of liver issues, kidney problems, stomach or intestinal complications, heart disorders (including sick sinus syndrome, bradycardia, AV block, and arrhythmias), respiratory or lung issues, seizures, or difficulties in urination due to an enlarged prostate.
This medication might cause dizziness or drowsiness. The consumption of alcohol or marijuana may exacerbate these effects. Refrain from operating vehicles, machinery, or engaging in activities that require alertness until you can do so safely.
Galantamine has the potential to cause QT prolongation, a condition affecting the heart rhythm. In rare cases, QT prolongation can lead to serious outcomes like fast or irregular heartbeat, and other symptoms (such as severe dizziness or fainting) that necessitate immediate medical attention. If you have low levels of potassium or magnesium in your blood, the risk of QT prolongation could increase. This risk might escalate further if you use specific drugs (like diuretics or “water pills”) or experience conditions like excessive sweating, diarrhea, or vomiting. Consult your doctor to ensure the safe usage of galantamine in such scenarios.
Elderly individuals may display greater sensitivity to the side effects of this medication, particularly with regard to QT prolongation.
In the context of pregnancy, this medication should only be utilized when deemed absolutely necessary. Discuss the potential risks and benefits with your doctor.
It remains uncertain whether this drug passes into breast milk. Seek guidance from your doctor prior to breastfeeding.
Form and Strength
Razadyne is available in the following forms and strengths:
-
galantamine tablet:
- 4mg
- 8mg
FAQ
What does Razadyne do for Alzheimer’s?
Razadyne acts to reversibly block acetylcholinesterase, which allows for the levels of acetylcholine to increase naturally. This treatment has only been seen to alleviate the symptoms of AD, but cannot stop the progression of the disease.
What should be monitored when taking Razadyne?
Since Razadyne may cause loss of appetite and weight loss, your doctor should monitor your weight before and during treatment with this medication.
Resources
- https://alzheimersnewstoday.com/alzheimers-disease-treatment/approved-drugs/razadyne-galantamine/#:~:text=Razadyne%20acts%20to%20reversibly%20block,the%20progression%20of%20the%20disease
- https://medlineplus.gov/druginfo/meds/a699058.html
- https://www.webmd.com/drugs/2/drug-93285/razadyne-oral/details
- https://www.mayoclinic.org/drugs-supplements/galantamine-oral-route/side-effects/drg-20067458?p=1
- https://www.drugs.com/razadyne.html
