Prescription Required 
Formulation : 
Description
Indications
Colestipol is employed in conjunction with dietary modifications to reduce the levels of fatty substances, specifically low-density lipoprotein (LDL) cholesterol (commonly referred to as ‘bad cholesterol’), in individuals with elevated cholesterol levels. This medication belongs to a category of drugs known as bile acid sequestrants. Its mechanism of action involves binding to bile acids in the intestines, forming a compound that is subsequently eliminated from the body.
Uses and Dosage
Colestipol is available in tablet and granule forms for oral administration. Tablets are typically taken once or twice a day, while granules may be taken one to six times daily.
Adhere to the prescribed dosage of colestipol and avoid taking more or less or increasing the frequency beyond your doctor’s recommendation.
Unless otherwise advised, take other medications at least 1 hour before or 4 hours after colestipol to prevent interference with their absorption.
Swallow the tablets whole with a glass of water or another liquid; do not chew, split, or crush them.
Your doctor may adjust your dose gradually at intervals of 1 to 2 months based on your response.
Continue taking colestipol even if you feel well, and do not discontinue it without consulting your doctor.
When taking the granules, avoid consuming them dry. Mix them with at least 3 ounces (90 milliliters) of a liquid (e.g., fruit juice, water, milk, or a soft drink) and stir until thoroughly combined. If using a carbonated beverage, mix it slowly in a large glass to minimize foaming. After the dose, rinse the glass with a small amount of additional liquid and drink it to ensure you receive the full dose.
Colestipol can also be mixed with hot or regular breakfast cereals, thin soups (e.g., tomato and chicken noodle), or pulpy fruits (e.g., crushed pineapple, pears, peaches, and fruit cocktail).
Side Effects
Some side effects may occur that usually do not need medical attention:
- belching
- bloating
- constipation
- diarrhea
- dizziness
- drowsiness
- fatigue
- gas
- headache
- heartburn
- loss of appetite
Inform your healthcare provider immediately if you experience any serious side effects:
- anxiety
- bleeding or worsening hemorrhoids
- chest pain
- increased heart rate
- increased liver enzymes
- joint, muscle, or back pain
- rapid heartbeat
- shortness of breath
- black, tarry stools
- blood in stools
- stomach pain with nausea and vomiting
Caution
- Before starting colestipol, inform your doctor or pharmacist about any allergies you may have, as this product may contain inactive ingredients that can trigger allergic reactions.
- Provide your medical history to your doctor or pharmacist, particularly if you have a history of constipation, hemorrhoids, or kidney disease.
- The flavored colestipol granules contain aspartame. If you have phenylketonuria (PKU) or any condition requiring restricted aspartame (or phenylalanine) intake, consult your doctor or pharmacist for guidance on using the flavored granules safely.
- Since this medication can affect the absorption of specific nutrients like folic acid and fat-soluble vitamins (A, D, E, K), your doctor may advise taking a multivitamin supplement. Seek your doctor’s guidance for more information.
- Older adults may be more susceptible to the side effects of this drug, particularly constipation.
- During pregnancy, use this medication only if necessary, as it may impact nutrient absorption. Discuss the risks and benefits with your doctor.
- While it is unlikely that this medication passes into breast milk, it may affect nutrient absorption. Consult your doctor before breastfeeding.
Form and Strength
Colestid Granules is available in the following forms and strengths:
- Colestid Granules granules:
- 5 mg
FAQ
How long does it take for Colestid Granules to start working?
It may take several weeks before you get the full benefit of this Colestid.
Why do I have to avoid taking other medications at the same time as Colestid?
Patients need to take other drugs at least one hour before or four hours after Colestid to avoid impeding their absorption.
Resources
- https://www.mayoclinic.org/drugs-supplements/colestipol-oral-route/precautions/drg-20068621?p=1#:~:text=Make%20certain%20your%20health%20care,diet%20your%20doctor%20gave%20you
- https://www.medbroadcast.com/drug/getdrug/colestid#adverseeffects
- https://www.webmd.com/drugs/2/drug-6727-111/colestid-oral/colestipol-granules-oral/details
- https://medlineplus.gov/druginfo/meds/a682157.html
- https://www.drugs.com/cdi/colestipol-granules.html
