Combivir (Lamivudine/zidovudine) Customer Reviews


Rx Prescription Required    RxFormulation : Tablet

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Generic alternative for Combivir


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The combination of lamivudine and zidovudine is utilized in conjunction with other medications for the treatment of human immunodeficiency virus (HIV) infection. Lamivudine and zidovudine belong to a class of pharmaceuticals known as nucleoside reverse transcriptase inhibitors (NRTIs). Their mechanism of action involves reducing the concentration of HIV in the bloodstream.

While the lamivudine and zidovudine combination does not provide a cure for HIV, it has the potential to diminish the likelihood of developing acquired immunodeficiency syndrome (AIDS) and HIV-associated conditions, including severe infections or cancer. When used in conjunction with safer sexual practices and the implementation of lifestyle modifications, these medications can contribute to a decrease in the risk of transmitting the HIV virus to other individuals.

Uses and Dosage

Adhere to the following instructions provided by your physician regarding the administration of this medication. Take it orally, with or without food, typically twice daily. Ensure that you consume a full glass of water (8 ounces/240 milliliters) unless otherwise instructed by your doctor.

Due to the fixed dosage of lamivudine and zidovudine in this combination product, it should only be used if your doctor has determined that the prescribed doses of both medications are suitable for your specific condition.

Children weighing less than 30 kilograms (66 pounds) should not use this product.

Follow your doctor’s instructions and continue taking this medication (along with other HIV medications) exactly as prescribed. Do not miss any doses, alter your dosage, exceed the recommended frequency, or discontinue the medication (or other HIV medicines), even temporarily, unless explicitly instructed by your doctor.

Skipping doses or modifying your regimen without proper medical approval may lead to increased viral levels, treatment-resistant infections, or exacerbated side effects.

For optimal results, take this medication at evenly spaced intervals. To assist with remembering, establish a consistent daily schedule for medication intake.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • headache
  • diarrhea
  • heartburn
  • difficulty falling asleep or staying asleep
  • depression
  • stuffy nose
  • cough
  • joint pain

Inform your healthcare provider immediately if you experience any serious side effects:

  • hives
  • rash
  • itching
  • difficulty breathing or swallowing
  • numbness, tingling, or burning in your fingers or toes
  • fever
  • wheezing


Prior to initiating lamivudine/zidovudine treatment, inform your doctor or pharmacist about any known allergies to either drug or other substances. This product may contain inactive components that could elicit allergic reactions or other complications.

Before commencing the use of this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of kidney problems, liver problems (such as hepatitis B or C, cirrhosis), pancreas disorders (pancreatitis), alcohol consumption, or low red/white blood cell counts.

This drug may induce dizziness. The consumption of alcohol or marijuana can intensify this effect. Refrain from driving, operating machinery, or engaging in activities that require alertness until you can do so safely.

Restrict alcohol consumption due to the increased risk of liver problems and pancreatitis.

Children may exhibit heightened sensitivity to the side effects of this medication, especially pancreatitis.

Inform your doctor if you are pregnant before initiating this medication. Treatment can diminish the risk of transmitting HIV infection to your baby. Discuss the potential risks and benefits with your doctor.

Lamivudine and zidovudine are excreted into breast milk. As breast milk can transmit HIV, do not breastfeed while using this medication.

Form and Strength

Combivir is available in the following forms and strengths:

  • Combivir tablet:

    • 150/300mg
  • lamivudine and zidovudine tablet:

    • 150/300mg


How effective is Combivir?

Combivir is very effective against HIV when taken every day with other HIV ARVs. All of the medications work together to lower the amount of virus in your body and prevent the virus from becoming resistant to the medications.

Does Combivir cause anemia?

Combivir can injure the bone marrow- the soft tissue inside bones where blood cells are made. As a result, Combivir can cause anemia.



Additional information

Generic name:

Lamivudine/Zidovudine, Lamivudine/zidovudine





Quantities Available:

60, 120

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Combivir (Lamivudine/zidovudine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Combivir (Lamivudine/zidovudine).