Depakene (Valproic Acid) Customer Reviews


Rx Prescription Required    RxFormulation : Delayed Release Capsule

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Generic alternative for Depakene

Valproic Acid

Rx Prescription Required    RxFormulation : Delayed Release Capsule

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Valproic acid is prescribed either as a monotherapy or in combination with other medications for the treatment of specific seizure types. This medication is also utilized in the management of manic episodes, characterized by heightened and abnormally excited mood, in individuals diagnosed with bipolar disorder. Valproic acid can additionally be employed as a preventive measure against migraine headaches, although it does not alleviate headaches that have already commenced. Valproic acid belongs to a pharmacological category known as anticonvulsants and operates by augmenting the levels of a specific naturally occurring substance in the brain.

Uses and Dosage

Take this medication orally. If you experience stomach upset, it is acceptable to take it with food. Swallow the capsule whole, avoiding any crushing or chewing, as this can cause irritation to the mouth or throat.

The appropriate dosage of this medication will be determined by factors such as your age, weight, medical condition, response to treatment, and concurrent use of other medications.

Consistent and regular use of this medication is important to derive maximum benefit from it. Remember to take it at the same time every day to maintain a steady level of the medication in your bloodstream.

If you are using this medication for seizures, do not discontinue it without consulting your doctor. Abrupt cessation of the drug may worsen your condition. Gradual dose reduction may be necessary under medical supervision.

This medication does not provide relief for acute migraine headaches. Follow your doctor’s instructions regarding the use of other medications specifically for acute migraine attacks.

If your condition does not improve, please inform your doctor.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • drowsiness
  • dizziness
  • headache
  • diarrhea
  • constipation
  • changes in appetite
  • weight changes
  • back pain
  • agitation
  • mood swings
  • abnormal thinking
  • uncontrollable shaking of a part of the body
  • problems with walking or coordination
  • uncontrollable movements of the eyes
  • blurred or double vision
  • ringing in the ears
  • hair loss

Inform your healthcare provider immediately if you experience any serious side effects:

  • unusual bruising or bleeding
  • tiny purple or red spots on the skin
  • fever
  • rash
  • bruising
  • hives
  • difficulty breathing or swallowing
  • swollen glands
  • swelling of face, eyes, lips, tongue, or throat
  • peeling or blistering skin
  • confusion
  • tiredness
  • vomiting
  • drop in body temperature
  • weakness or swelling in the joints


Prior to initiating valproic acid treatment, inform your doctor or pharmacist about any known allergies you may have, including allergies to valproic acid, divalproex, valproate sodium, or any other substances. This medication may contain inactive ingredients, such as peanut oil, that could trigger allergic reactions or other complications.

Before using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of liver disease, pancreatitis, certain metabolic disorders, alcohol abuse, bleeding disorders, brain disease (dementia), kidney disease, dehydration, or poor nutrition.

To minimize the risk of cuts, bruises, or injuries, exercise caution when handling sharp objects like razors and nail cutters, and avoid participating in activities that involve contact sports.

This medication may cause dizziness, drowsiness, or blurred vision. Consumption of alcohol or marijuana can intensify these effects. Refrain from driving, operating machinery, or engaging in tasks that require alertness or clear vision until you can safely do so.

Children under the age of 6 may face a higher risk of liver problems and pancreatitis.

Older adults may be more susceptible to the side effects of this medication, particularly drowsiness, dizziness, unsteadiness, or tremors. These effects can increase the risk of falls.

Inform your doctor if you are pregnant or planning to become pregnant. You should not become pregnant while using valproic acid, as it may harm an unborn baby. If you become pregnant, promptly consult your doctor regarding the risks and benefits associated with this medication.

This medication passes into breast milk. Although no harm to nursing infants has been reported, consult your doctor before breastfeeding.

Form and Strength

Depakene is available in the following forms and strengths:

  • valproic acid delayed-release capsule:

    • 250mg
    • 500mg


Does Depakene help with anxiety?

Depakene is only FDA-approved to treat certain types of seizures. There was one small study that showed that it might help with social anxiety disorder, but more research is needed.

How quickly does Depakene work?

While it only takes a few hours for your body to fully absorb Depakene, it can take a few weeks before you start to notice a difference in your symptoms.



Additional information

Generic name:

Valproic Acid


Capsule, Delayed Release Capsule


250mg, 500mg

Quantities Available:


Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Depakene (Valproic Acid). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Depakene (Valproic Acid).