Prescription Required 
Formulation : 
Description
Indications
Phenoxybenzamine is prescribed for the treatment of high blood pressure and excessive sweating caused by a specific tumor in the adrenal glands known as pheochromocytoma. It falls under the category of drugs called alpha blockers. The mechanism of action involves relaxing and widening blood vessels, facilitating smoother blood flow.
Uses and Dosage
Phenoxybenzamine is administered orally, with or without food, following your doctor’s instructions, typically 2 to 3 times a day. The prescribed dosage is determined by your medical condition and response to the treatment.
Consistency is key, so use this medication regularly to derive the maximum benefit. Taking it at the same times each day can help you remember. It’s important to continue taking the medication even if you feel well, as many individuals with high blood pressure may not experience noticeable symptoms.
Avoid discontinuing the medication abruptly without consulting your doctor, as doing so may worsen your condition. If your doctor decides to discontinue the medication, the dose may need to be gradually reduced.
Keep your doctor informed if your condition worsens, such as an increase in routine blood pressure readings. Regular communication with your healthcare provider ensures optimal management of your treatment plan.
Side Effects
Some side effects may occur that usually do not need medical attention:
- nasal congestion
- dizziness
- upset stomach
- sexual dysfunction (difficulty ejaculating)
- dizziness
Inform your healthcare provider immediately if you experience any serious side effects:
- fainting
- fast heartbeat
- vomiting
Caution
- Before taking phenoxybenzamine, inform your doctor or pharmacist if you are allergic to it, other alpha blockers (such as phentolamine), or any other substances. Inactive ingredients in the product may also cause allergic reactions or other complications.
- Share your medical history with your doctor or pharmacist, particularly if you have blood vessel disease, heart disease, kidney disease, lung infections, or specific eye problems (cataracts, glaucoma).
- This medication may induce dizziness or drowsiness. The use of alcohol or marijuana can intensify these effects. Refrain from activities requiring alertness, such as driving or using machinery, until you can do so safely.
- Older adults may be more susceptible to the side effects of this drug, particularly dizziness, which increases the risk of falling.
- During pregnancy, use this medication only when essential. Discuss the potential risks and benefits with your doctor.
- It’s unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.
Form and Strength
Dibenzyline is available in the following forms and strengths:
- phenoxybenzamine capsule:
- 10 mg
FAQ
How long does it take for Dibenzyline to start working?
Dibenzyline starts to work within several hours.
How does Dibenzyline work?
Dibenzyline works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Dibenzyline, the muscle relaxes and the blood vessels widen.
Resources
- https://go.drugbank.com/drugs/DB00925
- https://www.goodrx.com/phenoxybenzamine/what-is
- https://www.mayoclinic.org/drugs-supplements/phenoxybenzamine-oral-route/proper-use/drg-20065455?p=1
- https://www.webmd.com/drugs/2/drug-6757/dibenzyline-oral/details
- https://medlineplus.gov/druginfo/meds/a682059.html
- https://www.drugs.com/mtm/dibenzyline.html
