Diclectin (Doxylamine/pyridoxine hcl) Customer Reviews


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Generic alternative for Diclectin

Doxylamine/pyridoxine hcl

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The pairing of doxylamine and pyridoxine serves to alleviate nausea and vomiting in expectant mothers who have found no relief through dietary adjustments or alternative therapies. Doxylamine falls under the category of antihistamines, functioning by inhibiting the effects of specific natural compounds in the body known to trigger nausea and vomiting.

Pyridoxine, also known as vitamin B6, is administered due to its potential role in addressing deficiencies which might contribute to pregnancy-related nausea and vomiting.

Uses and Dosage

Follow your doctor’s instructions precisely when taking this medication. Typically, it should be taken orally on an empty stomach with a glass of water.

Initially, it’s often recommended to take it once daily at bedtime. If nausea persists the following day, your doctor might advise increasing the dosage to twice daily (morning and bedtime).

Avoid exceeding a total of 2 tablets per day.

Swallow the tablets whole; do not crush or chew them. Breaking them apart can cause the entire dose to be released at once, heightening the risk of side effects.

Do not abruptly discontinue this medication or alter your dosage without consulting your doctor, as certain conditions may deteriorate with sudden cessation. Adjustments to your dose should be made gradually.

Consistently use this medication to derive maximum benefit. Establish a routine by taking it at the same time(s) each day to aid in remembering.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • dry mouth, nose, and throat
  • drowsiness
  • headache
  • restlessness
  • dizziness
  • muscle pain or weakness
  • stomach pain
  • constipation
  • diarrhea
  • rash

Inform your healthcare provider immediately if you experience any serious side effects:

  • vision problems
  • blurred vision
  • dilated pupils (black circles in the centers of the eyes)
  • difficulty urinating or painful urination
  • fast, irregular, or pounding heartbeat
  • shortness of breath
  • confusion
  • seizures


  • Before starting this product, inform your doctor or pharmacist about any allergies you have, particularly to doxylamine or pyridoxine, or if you have other allergies. This product might contain inactive ingredients that could trigger allergic reactions or other complications.
  • Prior to using this medication, disclose your medical history to your doctor or pharmacist, especially if you have respiratory issues, eye conditions, gastrointestinal problems, or difficulties with urination.
  • This medication may induce dizziness, drowsiness, or blurred vision. Consumption of alcohol or marijuana can exacerbate these effects. Refrain from operating machinery, driving, or engaging in activities requiring alertness or clear vision until you can do so safely.
  • Using this product during pregnancy is considered safe.
  • Pyridoxine transfers into breast milk, while it’s uncertain whether doxylamine does. Doxylamine could potentially have adverse effects on a breastfeeding infant. Consult your doctor before breastfeeding.

Form and Strength

Diclectin is available in the following forms and strengths:

  • Diclectin tablet:
    • 10 mg / 10 mg
  • doxylamine and pyridoxine tablet:
    • 10 mg / 10 mg


How well does Diclectin work?

In a clinical study, morning sickness symptoms improved after 2 weeks of taking Diclectin.

Is Diclectin safe during the first trimester of pregnancy?

Yes. Diclectin is safe to take even if you’re in your first trimester of pregnancy.


  1. https://www.goodrx.com/diclegis/what-is#faqs
  2. https://www.medbroadcast.com/drug/getdrug/diclectin#:~:text=This%20medication%20is%20used%20to,or%20in%20several%20different%20forms
  3. https://www.mayoclinic.org/drugs-supplements/doxylamine-and-pyridoxine-oral-route/side-effects/drg-20060896?
  4. https://www.healthlinkbc.ca/medications/doxylaminepyridoxine-delayed-release-oral
  5. https://medlineplus.gov/druginfo/meds/a613045.html
  6. https://www.webmd.com/drugs/2/drug-144683-1914/doxylamine-pyridoxine-vit-b6-oral/doxylamine-pyridoxine-extended-release-oral/details

Additional information

Generic name:

Doxylamine/pyridoxine hcl





Quantities Available:


Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Diclectin (Doxylamine/pyridoxine hcl). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Diclectin (Doxylamine/pyridoxine hcl).