Epiduo Forte Gel (Adapalene Benzoyl Peroxide) Customer Reviews

Epiduo Forte Gel

Rx Prescription Required    RxFormulation : Gel

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This skin treatment is prescribed for managing acne. It combines adapalene, a retinoid, with benzoyl peroxide, an antibiotic and skin-exfoliating agent. The medication aims to diminish the quantity and intensity of acne pimples while facilitating the rapid healing of any emerging pimples. Adapalene influences cell growth, reducing swelling and inflammation. Meanwhile, benzoyl peroxide reduces acne-causing bacteria and induces skin dryness and peeling.

Uses and Dosage

Before applying this medication, ensure that you wash your hands thoroughly. Gently cleanse the affected skin using a mild or soapless cleanser, and then pat it dry. Follow your doctor’s instructions and apply a thin layer of the medication once daily. Use your fingertips to apply a small amount (approximately the size of a pea) to the affected areas of the skin.

Limit the application of this medication to the skin only; avoid the inner lip area, inside the nose/mouth, or on mucous membranes. Refrain from applying it to cut, scraped, sunburned, or eczema-affected skin.

Take care to prevent the medication from entering your eyes. In case of accidental contact, flush your eyes with ample water and consult your doctor if irritation persists. After application, wash your hands to minimize the risk of inadvertently transferring the medication to your eyes.

The prescribed dosage and treatment plan are contingent on your medical condition and response to treatment.

During the initial weeks of using adapalene, there may be an apparent worsening of acne as the medication addresses pimples forming beneath the skin.

Consistently use this medication to maximize its benefits, applying it at the same time each day. Do not exceed the recommended amount or frequency, as doing so will not expedite improvements and may heighten the likelihood of redness, peeling, and discomfort.

Inform your doctor if your condition does not improve or worsens.

Due to the potential skin absorption and risk to an unborn baby, pregnant women or those planning to conceive should avoid handling this medication.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • dry skin
  • burning, itching, redness, skin rash, swelling, or soreness at the application site

Inform your healthcare provider immediately if you experience any serious side effects:

  • flushing or redness of the skin
  • peeling
  • sunburn
  • unusually warm skin
  • chest tightness
  • cough
  • difficulty with swallowing
  • dizziness
  • fast heartbeat


  • Before utilizing this product, inform your doctor or pharmacist about any allergies you may have to adapalene, benzoyl peroxide, vitamin A-related drugs (such as other retinoids like isotretinoin), or any other allergens. This product might contain inactive ingredients that could trigger allergic reactions or other complications.
  • Prior to using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have other skin conditions like eczema.
  • Be aware that this drug may bleach hair or colored fabrics. Exercise caution when applying it near the hairline, while dressing, and when choosing towel and bed sheet colors, especially if leaving the product on the skin overnight.
  • This medication can heighten sensitivity to the sun. Restrict sun exposure, avoid tanning booths and sunlamps, and use sunscreen along with protective clothing outdoors. Notify your doctor promptly if you experience sunburn or skin blisters/redness. Wait until your skin fully recovers from sunburn before resuming use. Harsh weather conditions like wind or cold may also irritate the skin.
  • Refrain from undergoing electrolysis, waxing, or using chemical depilatories for hair removal on treated areas while using this product.
  • Due to potential skin absorption and the risk of harm to an unborn baby, pregnant women or those planning pregnancy should avoid handling this medication. Notify your doctor if you are pregnant or planning to conceive; it is advised not to become pregnant while using this medication due to potential harm to an unborn baby. If pregnancy occurs, discuss the risks and benefits with your doctor.
  • The passage of this drug into breast milk when applied to the skin is uncertain. Consult your doctor before breastfeeding.

Form and Strength

Epiduo Forte Gel is available in the following forms and strengths:

  • Epiduo Forte Gel gel:
    • 0.3 % / 2.5 %


How long does it take for Epiduo Forte Gel to work?

Based on patient reviews of this product, most users find that Epiduo has visibly improved their acne symptoms within 2 to 3 weeks.

Should you use Epiduo Forte Gel every night?

Initially, you should use the medicine every other night for the first two or three weeks. If you are tolerating the medicine OK then move up to every night.


  1. https://www.theindependentpharmacy.co.uk/acne/guides/epiduo-gel-reviews-what-real-users-think
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/207917Orig1s000lbl.pdf
  3. https://www.mayoclinic.org/drugs-supplements/benzoyl-peroxide-and-clindamycin-topical-application-route/side-effects/drg-20073165
  4. https://www.webmd.com/drugs/2/drug-169385/epiduo-forte-topical/details
  5. https://www.drugs.com/mtm/epiduo-forte-topical.html

Additional information

Generic name:

Adapalene Benzoyl Peroxide





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Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Epiduo Forte Gel (Adapalene Benzoyl Peroxide). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Epiduo Forte Gel (Adapalene Benzoyl Peroxide).