Malarone (Atovaquone/Proguanil) Customer Reviews


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Generic alternative for Malarone


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The atovaquone and proguanil combination medication serves the purpose of treating a specific type of malaria infection, a severe and potentially fatal condition transmitted by mosquitoes. It is also utilized as a prophylactic measure to prevent a particular type of malaria infection in travelers visiting areas with a high prevalence of the disease. Classified as antimalarials, atovaquone and proguanil function by effectively eradicating the causative organisms responsible for malaria infection.

Uses and Dosage

The atovaquone and proguanil combination is available in tablet form for oral administration. When using it as a malaria preventive measure, you typically begin taking it once daily, one or two days before traveling to a malaria-endemic region. Continue taking it throughout your stay in the area and for seven days after returning.

For malaria treatment, the usual regimen involves taking it once daily for three consecutive days. Always consume atovaquone and proguanil with food or a milky drink and strive to take it at the same time each day.

Take atovaquone and proguanil precisely as directed by your healthcare professional; avoid altering the dosage or frequency without medical guidance.

If swallowing the tablets poses challenges, they can be crushed and mixed with condensed milk just before consumption.

In the event of vomiting within 60 minutes after taking atovaquone and proguanil, administer another full dose to ensure proper intake.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • nausea
  • vomiting
  • diarrhea
  • stomach pain
  • loss of appetite
  • headache
  • dizziness
  • cough
  • mouth sores

Inform your healthcare provider immediately if you experience any serious side effects:

  • rash
  • hives
  • peeling or blistering skin
  • fever
  • swelling of the eyes, face, lips, tongue, throat, hands, feet, ankles or lower legs
  • difficulty breathing or swallowing
  • hoarseness or throat tightness


Prior to taking atovaquone/proguanil, inform your doctor or pharmacist about any allergies you may have to either atovaquone or proguanil, as well as any other allergies. This medication may contain inactive ingredients that could trigger allergic reactions or other complications.

Before commencing this medication, disclose your medical history to your doctor or pharmacist, particularly if you are currently experiencing diarrhea, vomiting, kidney problems, liver problems, mental/mood disorders, or have a history of seizures.

This drug has the potential to cause dizziness. Consuming alcohol or using marijuana may intensify this dizziness. As a precaution, avoid activities that require alertness, such as driving or operating machinery, until you can perform them safely.

During pregnancy, utilize this medication only when deemed necessary. Traveling to a malaria-endemic area while pregnant significantly increases the risk of adverse outcomes for both you and your baby. Discuss the benefits and risks of malaria prevention with your doctor before making any decisions.

It is unknown if atovaquone passes into breast milk. The proguanil in this medication passes into breast milk and the effects of this medication on a nursing infant are not known. The CDC recommends against using this product for malaria prevention if you are breastfeeding.

Form and Strength

Malarone is available in the following forms and strengths:

  • Malarone tablet:

    • 62.5/25mg
    • 250/100mg
  • atovaquone and proguanil tablet:

    • 250/100mg


How long should I take Malarone for?

The course should be started 1 or 2 days before entering a country with a risk of malaria; taken daily for the entire duration of your stay; and continued for 7 days after leaving the affected area.

Is Malarone well tolerated?

Malarone is well tolerated, and side effects are rare.



Additional information

Generic name:





62.5/25mg, 250/100mg

Quantities Available:

12, 24

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Malarone (Atovaquone/Proguanil). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Malarone (Atovaquone/Proguanil).