Natazia (estradiol valerate and estradiol valerate/dienogest) Customer Reviews


Rx Prescription Required    RxFormulation : Tablet

StrengthQuantity & PriceBuy Now
3mg, 1mg and 2mg/2mg, 2mg/3mg
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This blend of hormonal medication is employed to avert pregnancy. It incorporates two key hormones: dienogest, classified as a progestin, and estradiol valerate, categorized as an estrogen. Apart from their contraceptive function, birth control pills can promote menstrual regularity, reduce menstrual blood loss and pain, lower the likelihood of ovarian cysts, and even serve as a remedy for acne. Note that using this medication does not provide protection against sexually transmitted diseases.

Uses and Dosage

Consume this medication orally as instructed by your healthcare provider, typically once daily. Opt for a time of day that is easy to recall, and adhere to this schedule consistently.

Maintain the exact regimen prescribed by your doctor when taking this medication. Specific birth control pill brands exhibit variations in estrogen and progestin levels across different stages of the menstrual cycle. Refer to the package instructions to locate the initial tablet, commence with the first tablet in the pack, and observe the proper sequence.

Avoid skipping any doses, as the likelihood of pregnancy increases if pills are missed, if a new pack is started late, or if a pill is taken 12 hours beyond the usual time.

In case of vomiting or diarrhea within 3 to 4 hours of ingesting the tablet, consult the “What to Do if You Miss Tablets” section in the Patient Information Leaflet. Follow the guidelines as though you had missed a dose, as vomiting or diarrhea can hinder the tablet’s effectiveness.

Taking this medication after your evening meal or before bedtime could alleviate stomach discomfort or nausea. Alternatively, you can choose a different time of day that suits your memory. Regardless of the chosen dosing schedule, consistency is key—maintain a 24-hour interval between doses.

Your pill pack incorporates 26 pills with active medication and 2 reminder pills containing no medication. For 26 consecutive days, ingest one active pill (containing hormones) daily. After the last active pill, take one reminder pill daily for 2 days unless otherwise instructed by your doctor. Typically, your menstrual period will occur in the fourth week of the cycle. Following the last reminder tablet, start a new pack the next day, even if your period continues or is absent. Should your period not occur, seek advice from your doctor.

If this marks your first experience with this medication and you are not transitioning from another form of hormonal birth control (like patches or other birth control pills), commence with the first tablet on the initial day of your period. During the first usage cycle exclusively, implement an additional non-hormonal birth control method (such as condoms or spermicide) for the initial 9 days to avert pregnancy until the medication becomes fully effective.

For guidance on transitioning from alternative forms of hormonal birth control (e.g., patches or other birth control pills) to this product, consult your doctor or pharmacist. In case of any ambiguity, consult the Patient Information Leaflet or seek guidance from your healthcare provider.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • blemishes on the skin
  • increased weight
  • pimples
  • patchy brown or dark brown discoloration of the skin

Inform your healthcare provider immediately if you experience any serious side effects:

  • breast pain, discomfort, or tenderness
  • headache, severe and throbbing
  • irregular menstrual periods
  • nausea
  • normal menstrual bleeding occurring earlier, possibly lasting longer than expected
  • vomiting


Prior to initiating this medication, inform your healthcare provider or pharmacist about any allergies you have, particularly if you are allergic to estradiol, dienogest, estrogens, progestins, or if you have any other allergies. This product could contain inactive components that might trigger allergic reactions or other complications.

Before using this product, disclose your medical history to your doctor or pharmacist, especially if you have a history of blood clots, blood clotting disorders, high blood pressure, abnormal breast examinations, cancer (particularly endometrial or breast cancer), elevated cholesterol or triglyceride levels in the blood, depression, diabetes, a familial or personal history of angioedema (a specific swelling disorder), gallbladder issues, severe headaches or migraines, heart problems, a history of jaundice during pregnancy or while using hormonal birth control methods (like pills or patches), kidney disease, liver disease, stroke, edema, thyroid disorders, or unexplained vaginal bleeding.

For individuals with diabetes, be aware that this medication might influence your blood sugar levels. Regularly monitor your blood sugar as directed and share the results with your doctor. Promptly inform your doctor if you experience signs of elevated blood sugar such as increased thirst and urination. Your doctor might need to make adjustments to your diabetes treatment, exercise regimen, or dietary plan.

Inform your doctor if you have recently undergone surgery, are planning to have surgery, or anticipate being immobile for a prolonged period (such as during extended air travel). These circumstances elevate the risk of blood clot formation, particularly when using hormonal birth control. Depending on the situation, you may need to temporarily discontinue this medication or take special precautions.

This medication could lead to the development of patchy, dark areas on the face and skin (melasma). Exposure to sunlight may exacerbate this effect. Minimize sun exposure, avoid tanning equipment and sunlamps, and use sunscreen along with protective clothing while outdoors.

If you have nearsightedness or wear contact lenses, be aware that you may encounter visual problems or difficulties with your contact lenses. If these issues arise, get in touch with your eye doctor.

Following the discontinuation of birth control pills, it might take a while for you to conceive.

This medication should not be used during pregnancy. If you become pregnant or suspect that you might be pregnant, promptly inform your doctor. If you have recently given birth or experienced a pregnancy loss/abortion after the first 3 months, discuss reliable birth control options with your doctor. Determine when it’s safe to initiate birth control containing estrogen, such as this medication.

Be aware that this medication could potentially reduce breast milk production. A small amount may pass into breast milk and have undesirable effects on a nursing infant, consult your doctor before breastfeeding.

Form and Strength

Natazia is available in the following forms and strengths:

  • Natazia tablet:

    • 1mg
    • 2mg
    • 3mg


What type of birth control is Natazia?

Natazia is a combined contraceptive that contains two hormones: estradiol valerate (an estrogen) and dienogest (a progestin). Both hormones work together to prevent pregnancy.

How well does Natazia work to prevent pregnancy?

Based on two studies, 1 to 2 out of 100 females might get pregnant during the first year they use Natazia.



Additional information

Generic name:

estradiol valerate and estradiol valerate/dienogest




3mg, 1mg and 2mg/2mg, 2mg/3mg

Quantities Available:


Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Natazia (estradiol valerate and estradiol valerate/dienogest). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Natazia (estradiol valerate and estradiol valerate/dienogest).