Prescription Required 
Formulation : 
Description
Indications
Polyethylene glycol 3350 is employed to address intermittent constipation. This medication belongs to the category of osmotic laxatives. Its mechanism involves encouraging water retention within the stool, leading to an augmented frequency of bowel movements and a softened stool consistency, facilitating smoother passage.
Uses and Dosage
Consume this medication orally, typically once a day, or as per the guidance from your doctor or the instructions provided on the product packaging.
If you’ve been prescribed individual packets, mix the powder according to your doctor’s or pharmacist’s instructions. For those using the bulk bottle, employ the accompanying cap to measure the recommended dose. Blend the powder with a glass (approximately 4-8 ounces or 120-240 milliliters) of liquid, such as water, juice, soda, coffee, or tea. Ensure thorough stirring until the powder fully dissolves before consuming the solution. If uncertainties arise, don’t hesitate to consult your pharmacist.
This medication might impede the effectiveness of certain liquid thickeners, potentially elevating the risk of choking. If you’re using liquid thickeners in conjunction with this medication, confer with your pharmacist to select an appropriate thickener that won’t interact with the medication.
Following the initiation of this medication, it may take anywhere from 2 to 4 days before you experience a bowel movement. Do not escalate the dose or increase the frequency beyond what’s prescribed.
Refrain from utilizing this medication for over 2 weeks unless specifically directed by your doctor. Should your condition persist or worsen, notify your doctor. Extended or excessive use of laxatives can result in dependency and chronic constipation. Overuse can lead to diarrhea, dehydration, and imbalances in minerals like sodium.
For those using nonprescription polyethylene glycol to self-treat occasional constipation, if this treatment proves ineffective after 7 days, consult your doctor for further guidance on additional treatment options.
Side Effects
Some side effects may occur that usually do not need medical attention:
- nausea
- bloating
- cramping
- gas
Inform your healthcare provider immediately if you experience any serious side effects:
- diarrhea
- hives
Caution
Prior to commencing this medication, inform your doctor or pharmacist about any allergies you may have, particularly if you are allergic to polyethylene glycol, or if you have other known allergies. This product could contain inactive components capable of triggering allergic reactions or other complications.
Before initiating this medication, share your medical history with your doctor or pharmacist, particularly if you have a history of persistent nausea, vomiting, or abdominal pain, stomach or intestinal issues, or kidney disease.
The elderly population might exhibit increased sensitivity to the side effects of this drug, particularly diarrhea.
During pregnancy, this medication should be used only when the necessity is clear. Discuss the potential risks and benefits with your doctor.
The passage of this drug into breast milk is not fully understood. Consult your doctor before breastfeeding.
Form and Strength
Peg 3350 is available in the following forms and strengths:
-
polyethylene glycol powder:
- 238g
FAQ
How long does PEG 3350 take to work?
It may take 1 or 3 days for this medicine to help you have a bowel movement.
Does PEG 3350 cause dependence/tolerance when used long-term?
No. PEG 3350 works by keeping more water in the stool so it is softer and easier to pass. It does not work on the nerves or muscles of the gut and so does not cause any dependence or damage.
Resources
- https://www.mayoclinic.org/drugs-supplements/polyethylene-glycol-3350-and-electrolytes-oral-route/proper-use/drg-20062627#:~:text=You%20should%20have%20your%20first,after%20you%20drink%20the%20medicine
- https://www.healthlinkbc.ca/medications/polyethylene-glycol-peg-3350-oral
- https://medlineplus.gov/druginfo/meds/a603032.html
- https://www.webmd.com/drugs/2/drug-17118/polyethylene-glycol-3350-oral/details
- https://www.drugs.com/mtm/polyethylene-glycol-3350.html
