This medication combines two active ingredients, ertugliflozin and sitagliptin, and is prescribed alongside a balanced diet and exercise regimen to manage elevated blood sugar levels in individuals with type 2 diabetes.
Ertugliflozin operates by enhancing the elimination of sugar through the kidneys. In contrast, sitagliptin functions by elevating the levels of natural compounds known as incretins. Incretins play a pivotal role in regulating blood sugar levels by boosting insulin secretion, particularly following meals, and reducing the sugar production by the liver.
Uses and Dosage
Follow your doctor’s instructions for taking this medication, either with or without food, typically once daily in the morning. The prescribed dosage depends on your specific medical condition and how you respond to the treatment.
Consistently use this medication to maximize its effectiveness. To aid in remembering, take it at the same time every day.
If your condition does not improve or worsens (resulting in either excessively high or low blood sugar levels), inform your doctor promptly.
Some side effects may occur that usually do not need medical attention:
- arm, leg, or back pain
- increased frequency of urination
- increased need to urinate at night
- joint pain
- muscle aches
- sore throat
- stuffy or runny nose
Inform your healthcare provider immediately if you experience any serious side effects:
- decreased urine production
- blood in the urine
- painful or difficult urination)
- skin ulcers or sores
- painful, frequent, or urgent need to urinate
- odorous discharge under foreskin
- red, swollen, itchy head of the penis
- pain when urinating or during sexual activity
Before beginning this medication, please inform your doctor or pharmacist about any allergies you may have to ertugliflozin or sitagliptin, as well as any other known allergies. This product might contain inert ingredients that could potentially trigger allergic reactions or other complications.
Prior to using this medication, share your medical history with your doctor or pharmacist, paying special attention to the following: kidney disease or failure requiring dialysis, heart failure, instances of dehydration, low blood pressure, pancreas-related issues like pancreatitis, a history of alcohol use or abuse, gallbladder stones (gallstones), prior yeast infections in the vagina or penis, blockages or narrowing of blood vessels, often in the legs, nerve problems, existing foot sores or ulcers, or a history of amputation.
You might experience blurred vision, dizziness, or drowsiness as a result of extremely low or high blood sugar levels. Avoid activities that demand alertness, such as driving or operating machinery, until you are certain you can perform them safely.
While taking this medication, limit alcohol consumption because it can heighten the risk of experiencing low blood sugar and an elevated ketone level.
During periods of physical stress on your body, such as fever, infection, injury, or surgery, managing your blood sugar may become more challenging. If your dietary intake is reduced due to these circumstances or any illness, it can lead to a high ketone level while using this medication. In such cases, consult your doctor, as this may necessitate adjustments to your treatment plan, medications, or blood sugar and ketone monitoring.
Older adults may exhibit increased sensitivity to the side effects of this medication, particularly dizziness or fainting, dehydration, and kidney disease.
When pregnant, this medication should only be used when it is clearly necessary. Discuss the potential risks and benefits with your doctor.
Pregnancy can either induce or worsen diabetes. Collaborate with your doctor in devising a plan for managing your blood sugar during pregnancy, which may include modifications to your diabetes treatment, such as dietary changes and medications, including insulin.
The passage of this drug into breast milk is not well understood. Consult your doctor before breastfeeding.
Form and Strength
Steglujan is available in the following forms and strengths:
Steglujan film-coated tablet:
When is the best time to take Steglujan?
Steglujan should be taken once daily in the morning, with or without food.
How does Steglujan help with diabetes?
Steglujan helps remove sugar from the body through urination, helps to improve the levels of insulin after a meal and decreases the amount of sugar made by the body.