Prescription Required 
Formulation : 
Description
Indications
Abacavir is employed in combination with other medications to effectively treat human immunodeficiency virus (HIV) infection. Categorized under nucleoside reverse transcriptase inhibitors (NRTIs), abacavir operates by reducing the quantity of HIV in the bloodstream. While it does not provide a cure for HIV, it plays a crucial role in diminishing the likelihood of developing acquired immunodeficiency syndrome (AIDS) and HIV-related conditions, including serious infections or cancer.
Uses and Dosage
Take this medication orally, with or without food, as directed by your doctor, typically once or twice daily. If using the liquid form, carefully measure the dose with a specialized measuring device or spoon; avoid using a household spoon to ensure accurate dosing.
The prescribed dosage is contingent on your medical condition and how you respond to the treatment. For children, the dosage is also determined by their weight.
If you pause abacavir usage, even briefly, and then resume, there’s an elevated risk of experiencing a severe, potentially fatal allergic reaction. Ensure you refill your medication before running out and avoid discontinuing treatment unless instructed by your doctor. Before restarting abacavir, consult your doctor or pharmacist, and ensure you have easy access to medical care.
It’s crucial to adhere to the prescribed regimen, taking this medication (as well as other HIV medications) precisely as directed by your doctor. Do not skip doses, increase your dose, take it more frequently than prescribed, or stop taking it (or other HIV medicines) even briefly without your doctor’s approval. Deviating from the prescribed regimen may lead to increased virus levels, complicating the infection (resistance), or exacerbating side effects.
For optimal effectiveness, take this medication at evenly spaced intervals. To help with consistency, take it at the same time(s) every day.
Side Effects
Some side effects may occur that usually do not need medical attention:
- headache
- depression
- anxiety
- difficulty falling asleep or staying asleep
Inform your healthcare provider immediately if you experience any serious side effects:
- blisters or peeling skin
- hives
- itching
- difficulty swallowing or breathing
- excessive tiredness; weakness, dizziness or lightheadedness; fast or irregular heartbeat; muscle pain; stomach pain with nausea and vomiting; shortness of breath or difficulty breathing; flu-like symptoms such as fever, chills, or cough; or feeling cold, especially in the arms or legs
- light-colored bowel movements; yellowing of the skin or eyes; loss of appetite; unusual bleeding or bruising; dark yellow or brown urine; or pain in the upper right part of stomach
Caution
- Before taking abacavir, inform your doctor or pharmacist about any allergies you may have, as the product might contain inactive ingredients that can trigger allergic reactions or other issues.
- Prior to using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have liver problems (such as hepatitis B or C, or cirrhosis), kidney problems, or engage in alcohol use.
- Abacavir may heighten the risk of a heart attack. Engage in a discussion with your doctor about the risks and benefits of the treatment and ways to mitigate the risk of heart disease. Inform your doctor if you have heart problems, if you smoke, or if you have other conditions that elevate your risk of heart disease, such as high blood pressure, diabetes, or high cholesterol levels.
- Notify your doctor if you are pregnant before using this medication, as the treatment can reduce the risk of transmitting HIV infection to your baby. Have a thorough discussion about the risks and benefits with your doctor.
- This medication passes into breast milk, and as breast milk may transmit HIV. Consult your doctor before breastfeeding.
Form and Strength
Ziagen is available in the following forms and strengths:
- abacavir tablet:
- 300 mg
FAQ
When should I take Ziagen?
If you are taking Ziagen once a day, it can be taken any time during the day as long as it’s the same time everyday. If you are taking Ziagen twice a day, try to take each dose 12 hours apart from each other.
Does Ziagen cause weight gain?
Weight gain is not a common side effect with Ziagen.
