Anacin (Aspirin/caffeine - non Rx) Customer Reviews


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We don't sell this brand-version medication.

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This medication is formulated by combining aspirin and caffeine. Its purpose is to alleviate mild discomfort caused by different conditions, including headaches, toothaches, menstrual cramps, or muscle aches.

Aspirin is classified as a salicylate and a nonsteroidal anti-inflammatory drug (NSAID) known for its pain-relieving and anti-inflammatory properties. By reducing pain and swelling, it provides relief. Caffeine can potentially enhance the pain-relieving effects of aspirin.

Uses and Dosage

Prescription aspirin is available in the form of extended-release tablets designed for long-acting effects. Nonprescription aspirin comes in various forms such as regular tablets, delayed-release tablets, chewable tablets, powder, and gum, all intended for oral consumption.

The frequency of intake for prescription aspirin is typically two or more times a day, while nonprescription aspirin is generally taken once daily to reduce the risk of heart attack or stroke. For the treatment of fever or pain, nonprescription aspirin is usually taken every 4 to 6 hours as needed. Adhere strictly to the prescribed dosage and do not exceed or decrease it without guidance from the package label or your doctor.

When taking extended-release tablets, swallow them whole with a full glass of water. Do not break, crush, or chew them.

Delayed-release tablets should be swallowed with a full glass of water.

Chewable aspirin tablets can be chewed, crushed, or swallowed whole. After taking these tablets, drink a full glass of water immediately.

Consult a doctor before administering aspirin to a child or teenager, as it may lead to Reye’s syndrome—a serious condition involving the accumulation of fat in the brain, liver, and other organs, particularly if the individual has a viral infection such as chickenpox or the flu.

If you have undergone oral surgery or had your tonsils removed within the past 7 days, discuss with your doctor which types of aspirin are safe for you.

Delayed-release tablets take some time to take effect. Avoid using them for the rapid relief of fever or pain.

Discontinue aspirin usage and contact your doctor if your fever persists for more than 3 days, your pain persists for more than 10 days, or if the previously affected body part becomes red or swollen. Such symptoms may indicate a condition requiring medical treatment.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • nausea
  • vomiting
  • stomach pain
  • heartburn

Inform your healthcare provider immediately if you experience any serious side effects:

  • hives
  • rash
  • swelling of the eyes, face, lips, tongue, or throat
  • wheezing or difficulty breathing
  • hoarseness
  • fast heartbeat
  • fast breathing
  • cold, clammy skin
  • ringing in the ears
  • loss of hearing
  • bloody vomit
  • vomit that looks like coffee grounds
  • bright red blood in stools
  • black or tarry stools


Prior to consuming this product, inform your doctor or pharmacist about any known allergies to caffeine, aspirin, other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, celecoxib, other salicylates like choline salicylate, or any other known allergies. Inactive ingredients present in the product may cause allergic reactions or other complications.

Before initiating the use of this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of stomach problems such as ulcers, heartburn, or stomach pain, aspirin-sensitive asthma, nasal polyps, bleeding or blood clotting disorders, gout, heart problems, high blood pressure, kidney disease, liver disease, or certain enzyme deficiencies (such as pyruvate kinase or G6PD deficiency).

This medicine has the potential to cause stomach bleeding. Regular consumption of alcohol and tobacco, particularly when combined with this medication, may increase the risk of stomach bleeding. Limit alcohol intake and cease smoking.

This medication contains aspirin. Children and teenagers under 18 years old should refrain from taking aspirin if they have chickenpox, the flu, any undiagnosed illness, or if they have recently received a vaccine. In these instances, the use of aspirin increases the risk of Reye’s syndrome, a rare but serious condition.

Older adults may exhibit increased sensitivity to the side effects of this medication, particularly in terms of stomach ulcers or bleeding, as well as sleep disturbances.

For women of childbearing age, discuss the benefits and risks of this medication with their doctor(s) before usage. Inform your doctor if you are currently pregnant or planning to conceive. This medication may be harmful to an unborn baby and could lead to complications during labor and delivery. Its use is not recommended during pregnancy from 20 weeks until delivery. If your doctor determines that you need to use this medication between 20 and 30 weeks of pregnancy, the lowest effective dose should be utilized for the shortest duration possible. This medication should not be used after 30 weeks of pregnancy.

This medication can pass into breast milk and may harm a nursing infant. Breastfeeding while using this drug is not recommended. Consult your doctor before breastfeeding.

Form and Strength

Anacin is available in the following forms and strengths:

    Anacin tablet:

    • 325mg


What are 3 benefits of taking Anacin?

Anacin can be used for relieving pain, lowering fever and reducing inflammation.

How much Anacin can I take a day?

Adults should not take more than 4000 milligrams (4 grams) of acetaminophen a day. People with liver problems and children should take less acetaminophen.



Additional information

Generic name:

Aspirin/caffeine – non Rx





Quantities Available:


Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Anacin (Aspirin/caffeine - non Rx). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Anacin (Aspirin/caffeine - non Rx).