Almotriptan is indicated for the management of symptoms associated with migraine headaches, characterized by intense pulsating pain often accompanied by sensitivity to light and sound, as well as nausea. This medication belongs to the class of drugs known as selective serotonin receptor agonists. Its mechanism of action involves the constriction of blood vessels surrounding the brain, thereby impeding the transmission of pain signals to the brain. It additionally inhibits the release of specific endogenous substances responsible for inducing pain, nausea, and other migraine-related symptoms.
Uses and Dosage
Almotriptan is administered orally in the form of tablets. It is typically taken promptly upon the initial manifestation of a migraine headache. In the event that symptoms improve following the intake of almotriptan but reoccur after a duration of two hours or longer, a second tablet may be taken. However, if symptoms persist without improvement subsequent to almotriptan administration, refrain from taking an additional tablet until consulting with a medical professional.
Your doctor will provide instructions regarding the maximum number of tablets permissible within a 24-hour timeframe. Almotriptan must be taken precisely as directed, neither exceeding nor reducing the prescribed dosage frequency.
For the initial dose of almotriptan, it may be recommended to administer it under medical supervision in a doctor’s office or another healthcare facility where potential serious reactions can be closely monitored.
Contact your doctor if your headaches fail to improve or occur with increased frequency subsequent to almotriptan usage.
Prolonged or excessive utilization of almotriptan beyond the recommended duration may exacerbate headaches or lead to an increased frequency of occurrence. Refrain from taking almotriptan or any other headache medication for more than ten days per month.
If the need arises to utilize almotriptan for the treatment of more than four headaches within a one-month period, consult your doctor.
Some side effects may occur that usually do not need medical attention:
- upset stomach
- dry mouth
Inform your healthcare provider immediately if you experience any serious side effects:
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- tightness, pain, pressure, or heaviness in the chest, throat, neck, or jaw
- slow or difficult speech
- weakness or numbness of an arm or leg
- sudden or severe stomach pain
- bloody diarrhea
- rapid, pounding, or irregular heartbeat
- shortness of breath
- breaking out in a cold sweat
- difficulty breathing or swallowing
- paleness or blue color of the fingers and toes
- pain, burning, or tingling in the hands or feet
Before taking almotriptan, tell your doctor or pharmacist if you are allergic to it, to other triptan migraine drugs, or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems, certain types of headaches (hemiplegic or basilar migraine), heart problems, stroke or “mini-stroke” (transient ischemic attack), kidney disease, liver disease.
Certain conditions can increase your risk for heart problems. Tell your doctor if you have any of these conditions, including: diabetes, family history of heart disease, high blood pressure, high cholesterol, overweight, smoker, postmenopausal (women), age more than 40 years (men).
This drug may make you dizzy or drowsy. Alcohol or marijuana can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.
The risk of heart disease, liver disease, and high blood pressure increases with age. Older adults may be more sensitive to the side effects of this drug, especially increased blood pressure and heart problems.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.
It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
Form and Strength
Axert is available in the following forms and strengths:
How long does it take for Axert to work?
Axert generally works within 30 minutes to 2 hours.
Can you take ibuprofen or naproxen with Axert?
Though there are no known risks if you take them together, talk to your healthcare provider before taking almotriptan with ibuprofen or naproxen. In certain situations, the combined use of triptans and NSAIDs is recommended depending on the severity of your migraine.