Januvia (sitagliptin) is an oral medication used to improve glycemic control on patients with type-2 diabetes mellitus, along with proper diet and regular exercise. By controlling high blood sugar levels, conditions like blindness, kidney damage, heart attack, nerve problems, loss of limbs, and sexual dysfunction could be prevented.
This oral tablet is a DPP (dipeptidyl-peptidase)-4 inhibitor that slows down the inactivation of incretin hormones. Januvia increases and extends the action of incretin hormones, namely glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide. This mechanism of action increases insulin and decreases the amount of glucagon in a glucose-dependent manner.
Before starting to take Januvia, read the prescription or medication guide provided. Take the exact dosage and frequency prescribed by your physician. This drug is available in Januvia 25 mg, Januvia 50 mg, and Januvia 100 mg tablet forms.
Take Januvia orally, with or without a meal, and at any time of the day. Although, it is best to take it at the same time each day to avoid missing a dose. Also, note that proper diet and regular exercise are necessary to achieve the full benefits of this medication.
Remember to monitor your blood sugar regularly. Contact your physician right away if the result is too high or too low. The dosage of Januvia medication may change based on your condition or how you respond to treatment.
Some of the common Januvia side effects include:
These usual side effects are often mild and disappear in a few days. If these common side effects worsen or if you experience severe adverse reactions, you have to seek medical attention immediately. Some severe side effects include decreased urine output, shortness of breath, severe stomach pain, persistent vomiting, loss of appetite, and increased heart rate.
Avoid taking Januvia if you have a known allergy to sitagliptin or any inactive ingredients this medication may have. Some signs of allergy to look out for are skin rash, hives, severe headache, and breathing difficulty. If you suspect an allergy, discontinue medication right away and seek emergency help.
Talk to your physician about the medical conditions you have at present or if you have a history of pancreatitis, kidney disease, gallstones, and heart failure. These medical conditions or any drugs you are taking may affect how you respond to this drug.
Watch out for signs of hypoglycemia or low blood sugar when taking Januvia. Signs of hypoglycemia are dizziness, shaking, sweating, palpitation, tingling of hands and feet, and blurred vision. To prevent this, limit your alcohol intake, avoid unusually heavy physical activities, take regular meals, and do not skip meals. If you experience hypoglycemia, take any form of glucose like table sugar, fruit juice, or regular soda.
If you get pregnant while taking Januvia, consult your doctor right away. Pregnancy might cause or worsen diabetes. Thus, your physician may change the drug of choice for you while pregnant.
Frequently Asked Questions
What is Januvia?
Januvia is a maintenance medication for people with type-2 diabetes.
Can Januvia be used in Type-1 diabetes or diabetic ketoacidosis?
No, Januvia should not be used for Type-1 diabetes and diabetic ketoacidosis.
Can children use Januvia?
Januvia is not being prescribed to patients younger than 18.
What should I do if I miss a dose of Januvia?
If you miss a dose of Januvia tablet, take it right away. However, if you’re close to your next dose, skip the missed dose and proceed with your regular schedule.
How much does Januvia cost?
You can check the price of Januvia at the top of this page.