Prescription Required 
Formulation : 
Description
Indications
Bempedoic acid is combined with lifestyle adjustments (diet, weight loss, exercise) and specific cholesterol-lowering medications to further reduce low-density lipoprotein (LDL) cholesterol in the bloodstream of adult individuals with familial heterozygous hypercholesterolemia (HeFH).. Bempedoic acid belongs to the category of drugs called adenosine triphosphate-citrate lyase (ACL) inhibitors. Its mechanism involves hindering the liver’s production of cholesterol.
Uses and Dosage
Administer this medication orally, with or without food, following your doctor’s instructions, typically once a day.
Consistently take this medication to derive the maximum advantages. Ensure you adhere to the same daily schedule. Continue using this medication even if you’re in good health. Many individuals with elevated cholesterol levels may not experience symptoms.
It remains crucial to maintain your commitment to dietary and exercise guidelines as advised by your doctor. The complete benefits of this medication may become apparent after up to 12 weeks.
Side Effects
Some side effects may occur that usually do not need medical attention:
- muscle spasms
- back pain
- pain in hands or feet
Inform your healthcare provider immediately if you experience any serious side effects:
- severe pain, redness, warmth, tenderness, or swelling of the joints, especially in the big toe area
- hearing or feeling a snap or pop in a tendon area; bruising after an injury to a tendon area; or inability to move to or bear weight on affected tendon area
Caution
Prior to starting bempedoic acid, inform your doctor or pharmacist about any existing allergies you might have, including allergies to this medication. This product could encompass inactive components that have the potential to trigger allergic reactions or other complications.
Before utilizing this medication, share your medical history with your doctor or pharmacist, particularly if you have a history of liver disease, kidney disease, gout, or tendon issues.
Elderly individuals may display heightened sensitivity to this drug’s side effects, particularly concerning tendon problems.
Notify your doctor if you are pregnant or considering pregnancy. Usage of bempedoic acid during pregnancy is discouraged. It may pose a risk to an unborn baby. If you become pregnant, promptly consult your doctor to evaluate the medication’s risks and benefits.
The transmission of this medication into breast milk is uncertain. Due to potential risks for the infant, avoid breastfeeding while using this drug.
Form and Strength
Nexletol is available in the following forms and strengths:
-
bempedoic acid tablet:
- 180mg
FAQ
Is Nexletol a statin drug?
No, Nexletol isn’t a statin drug. Nexletol belongs to a class of drugs called adenosine triphosphate-citrate lyase (ACL) inhibitors.
Does Nexletol raise blood pressure?
Nexletol does not cause high blood pressure (hypertension) as a side effect according to the manufacturer’s package insert.
Resources
- https://www.medicalnewstoday.com/articles/nexletol#fa-qs
- https://medlineplus.gov/druginfo/meds/a620020.html
- https://www.webmd.com/drugs/2/drug-178906/nexletol-oral/details
- https://www.mayoclinic.org/drugs-supplements/bempedoic-acid-oral-route/description/drg-20484223
- https://www.drugs.com/nexletol.html
