Prescription Required 
Formulation : 
Description
Indications
This combined medication is prescribed in conjunction with a balanced diet to aid in the reduction of “bad” cholesterol, specifically low-density lipoprotein (LDL). Ezetimibe functions by decreasing the absorption of cholesterol from the diet, thereby reducing the overall cholesterol intake by the body. Rosuvastatin belongs to the statin class of drugs and works by lowering the production of cholesterol in the liver. To optimize the effectiveness of this medication, implement additional lifestyle changes, including adhering to a proper diet that is low in cholesterol and fat.
Uses and Dosage
Follow your doctor’s instructions and take this medication orally, with or without food, typically once daily. Ensure you swallow the tablets whole and do not crush, chew, or dissolve them.
The prescribed dosage is determined by factors such as your medical condition, response to treatment, race, and concurrent medications. Inform your doctor and pharmacist about all the products you use, including prescription drugs, nonprescription drugs, and herbal products.
If you are of Asian descent, your doctor might advise starting with a lower dose due to potential increased sensitivity to the medication.
If you are also taking a bile acid sequestrant (such as cholestyramine or colestipol), schedule the intake of this product at least 2 hours before or 4 hours after the bile acid sequestrant. These medications may bind to ezetimibe/rosuvastatin, hindering full absorption.
Antacids containing aluminum and magnesium can reduce the absorption of this drug. If using such an antacid, take it at least 2 hours after taking this medication.
For optimal benefits, take this medication regularly at the same time each day. Continue taking it even if you feel well, as individuals with high cholesterol often do not experience noticeable symptoms.
It is crucial to adhere to your doctor’s advice regarding diet and exercise. The full benefits of this product may take up to 4 weeks to become evident.
Side Effects
Some side effects may occur that usually do not need medical attention:
- headache
- nausea
- muscle pain
- joint pain
- dizziness
- weakness
- constipation
- abdominal pain
Inform your healthcare provider immediately if you experience any serious side effects:
- difficulty in moving
- joint pain or swelling
- muscle pain, cramps, spasms, or stiffness
- constipation
- darkened urine
- ear congestion
- fast heartbeat
- fever
- irritation
- lack or loss of strength
- large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- loss of appetite
- loss of voice
- bleeding gums
- blistering, peeling, loosening of the skin
- blood in the urine or stools
- burning, crawling, itching, numbness, painful, prickling, “pins and needles”, or tingling feelings
- clay-colored stools
- sores, ulcers, or white spots in the mouth or on the lips
- stomach fullness
- unsteadiness or awkwardness
- unusual bleeding or bruising
- vomiting of blood
- weakness in the arms, hands, legs, or feet
Caution
- Before starting this medication, inform your doctor or pharmacist about any allergies you may have, whether to ezetimibe, rosuvastatin, or any other substances. Inactive ingredients in this product could potentially trigger allergic reactions or other complications.
- Prior to using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of liver disease, kidney disease, or alcohol use.
- Limit your consumption of alcoholic beverages while using this product, as daily alcohol use may heighten the risk of liver problems, especially when combined with this medication. Seek more information from your doctor or pharmacist about the potential risks.
- Older adults may be more susceptible to the side effects of this drug, particularly muscle problems.
- During pregnancy, use this medication only when it is clearly necessary, as it may pose a risk to an unborn baby. Discuss the potential risks and benefits with your doctor.
- The passage of this medication into breast milk is uncertain. Due to the potential risk to the infant, it is not recommended to breastfeed while using this medication. Consult your doctor before breastfeeding.
Form and Strength
Roszet is available in the following forms and strengths:
- Roszet:
- ezetimibe and rosuvastatin:
FAQ
What’s the best time of day to take Roszet?
Since Roszet contains rosuvastatin and is a long-acting medication, you can take it any time during the day or at night time.
Can I take Roszet with food?
You can take Roszet with or without food. If it’s hurting your stomach, try taking it with food to help. And unlike Vytorin, you don’t need to avoid eating grapefruit while taking Roszet.
