Prescription Required 
Formulation : 
Description
Indications
Propylthiouracil belongs to a group of medications known as antithyroid agents and is utilized to manage hyperthyroidism. This is a health condition that manifests when the thyroid gland generates an excessive amount of thyroid hormone, leading to an accelerated metabolism and the onset of specific symptoms.
Propylthiouracil is appropriate for treating hyperthyroidism in adults as well as children aged six years or older. Its mechanism of action involves inhibiting the production of thyroid hormone by the thyroid gland.
Uses and Dosage
Follow your doctor’s instructions when taking this medication, either with or without food, usually three times a day (every eight hours). The dosage is determined by your medical condition and response to treatment.
Take this medication precisely as prescribed. Do not exceed the prescribed dosage or take it more frequently than advised, as doing so will not accelerate your recovery and may increase your risk of side effects.
For optimal results, take this medication regularly at the same time each day, and do not discontinue its use without consulting your doctor.
If your condition does not improve or worsens, inform your doctor.
Side Effects
Some side effects may occur that usually do not need medical attention:
- hair loss
- difficulty tasting food
- numbness, burning, or tingling of the hands or feet
- joint or muscle pain
- dizziness
- swelling of the neck
Inform your healthcare provider immediately if you experience any serious side effects:
- sore throat, fever, chills, cough, or other signs of infection
- headache
- skin rash, hives, blisters, bumps or peeling
- dark, rust-colored, brown or foamy urine
- swelling of the face, eyes, stomach, arms, hands, feet, ankles, or lower legs
- chest pain
- shortness of breath or wheezing
- coughing up blood
Caution
Before taking propylthiouracil, notify your doctor or pharmacist of any allergies you may have, including allergies to this medication or any inactive ingredients. Inactive ingredients in the medication can trigger allergic reactions or other complications.
Inform your doctor or pharmacist about your medical history, particularly if you have blood disorders like agranulocytosis or thrombocytopenia, or if you have liver disease, before using this medication.
During the first three months of pregnancy, use this medication only when necessary. It is not recommended for use during the last six months of pregnancy. Your physician may instruct you to use an alternative medication during this time.
Discuss the benefits and drawbacks with your doctor if you are considering pregnancy, already pregnant, or believe you may be pregnant.
Propylthiouracil passes into breast milk. Consult your physician before breastfeeding.
Form and Strength
Propylthiouracil is available in the following forms and strengths:
-
Propylthiouracil tablet:
- 50mg
FAQ
How long does it take for Propylthiouracil to work?
Signs of improvement are usually seen within 3 weeks of the start of treatment.
How long do I need to take Propylthiouracil for?
Propylthiouracil usually needs to be taken for a period lasting between 6 months and 3 years.
Resources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5804720/#:~:text=Usually%20it%20is%20limited%20to,to%20complete%20resolution%20of%20symptoms
- https://www.webmd.com/drugs/2/drug-8883/propylthiouracil-oral/details
- https://www.mayoclinic.org/drugs-supplements/propylthiouracil-oral-route/description/drg-20072978
- https://medlineplus.gov/druginfo/meds/a682465.html#:~:text=Propylthiouracil%20is%20used%20to%20treat,of%20medications%20called%20antithyroid%20agents
- https://www.drugs.com/mtm/propylthiouracil.html
