Prescription Required 
Formulation : 
Description
Indications
This combination medicine comprises amlodipine and atorvastatin. Amlodipine is classified as a calcium channel blocker. Its mechanism of action involves reducing blood pressure and alleviating the strain on the heart by inducing relaxation in the blood vessel walls. Atorvastatin belongs to the category of medications referred to as HMG CoA reductase inhibitors, commonly known as “statins”. Atorvastatin functions by obstructing the activity of an enzyme required for cholesterol production within the body.
When used in conjunction with a balanced diet and regular exercise, this combined medication works effectively for the purpose of lowering blood pressure and managing angina, a condition characterized by chest pain, and managing your cholesterol levels.
Uses and Dosage
Adhere to the following instructions provided by your doctor regarding the administration of this medication. Take it orally, with or without food, as directed. Typically, it is taken once daily.
The appropriate dosage will be determined based on your medical condition, response to treatment, age, and concurrent use of other medications.
While using this medication, avoid consuming grapefruit or grapefruit juice unless explicitly advised by your doctor or pharmacist. Grapefruit has the potential to heighten the risk of experiencing side effects associated with this medicine.
If you are also taking specific medications to lower cholesterol levels (such as bile acid-binding resins like cholestyramine or colestipol), take this product at least 1 hour before or 4 hours after consuming those medications. These products can interact with atorvastatin, hindering its complete absorption.
In order to derive the maximum benefit from this medication, it should be taken regularly. Remember to take it at the same time every day. The full benefits of amlodipine may take up to 2 weeks to manifest, while the full benefits of atorvastatin may take up to 4 weeks.
Continue taking this medication even if you feel well. It is common for individuals with high blood pressure or high cholesterol/triglyceride levels to not exhibit symptoms of illness.
If this product is being used to manage chest pain, regular and consistent usage is imperative for optimal effectiveness. It should not be employed to alleviate chest pain during an episode.
Inform your doctor if your condition does not improve or if it worsens, such as persistent high blood pressure readings, increasing blood pressure, or more frequent occurrences of chest pain.
Side Effects
Some side effects may occur that usually do not need medical attention:
- ankle swelling
- constipation or diarrhea
- difficulty sleeping
- dizziness, especially when getting up from a sitting or lying position
- drowsiness or fatigue
- erectile difficulties
- gas
- general feeling of being unwell
- hair loss
- headache
- loss of appetite
- nausea or vomiting
- neck pain
- nightmares
- ringing in the ears
- skin rash
- stomach pain or upset
Inform your healthcare provider immediately if you experience any serious side effects:
- change in heart rhythm or increased heart rate
- changes in vision
- confusion
- cough
- fever
- increased occurrence or severity of chest pains
- loss of strength
- numbness or tingling sensation in the hands or fingers
- palpitations (pounding or racing heartbeat)
- poor memory
- shortness of breath
- generalized weakness
Caution
Prior to initiating the use of this product, inform your doctor or pharmacist about any known allergies to amlodipine, atorvastatin, other calcium channel blockers (such as nifedipine), or any other substances. Inactive ingredients present in this product can potentially trigger allergic reactions or other complications.
Before commencing this medication, disclose your complete medical history to your doctor or pharmacist, particularly if you have a history of liver disease, kidney disease, alcohol consumption, or specific structural heart conditions.
This medication may induce dizziness. The consumption of alcohol or marijuana can intensify this effect. Refrain from driving, operating machinery, or engaging in activities that require alertness until you can safely do so.
Limit your intake of alcoholic beverages. Regular alcohol consumption, especially when combined with atorvastatin, may heighten the risk of liver problems.
To minimize the risk of dizziness and lightheadedness, rise slowly when transitioning from a seated or lying position.
The elderly population may exhibit increased sensitivity to the side effects of the medication, particularly muscle problems and dizziness.
During pregnancy, this medication should only be used when absolutely necessary. It has the potential to harm the unborn baby. Discuss the risks and benefits with your doctor.
Amlodipine can pass into breast milk, while it is uncertain if atorvastatin does as well. Due to the potential risks to the infant, it is not recommended to breastfeed while using this product.
Form and Strength
Caduet is available in the following forms and strengths:
-
Caduet tablet:
- 5/10mg
- 5/20mg
- 5/40mg
- 5/80mg
- 10/10mg
- 10/20mg
- 10/40mg
- 10/80mg
-
amlodipine and atorvastatin tablet:
- 5/10mg
- 5/20mg
- 5/40mg
- 5/80mg
- 10/10mg
- 10/20mg
- 10/40mg
- 10/80mg
FAQ
How long does it take for Caduet to work?
It usually takes 2 to 4 weeks to affect blood pressure and cholesterol levels.
Do you have to take Caduet at night?
Unlike other similar medications, Caduet can be taken at any time of the day. This is because it stays in your body longer than some other similar medications.
Resources
- https://www.goodrx.com/caduet/what-is#faqs
- https://www.medbroadcast.com/drug/getdrug/caduet#adverseeffects
- https://www.webmd.com/drugs/2/drug-88964/caduet-oral/details
- https://www.mayoclinic.org/drugs-supplements/amlodipine-and-atorvastatin-oral-route/description/drg-20062902
- https://www.drugs.com/caduet.html
