Cafergot (Caffeine/Ergotamine) Customer Reviews


Rx Prescription Required    RxFormulation : Tablet

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This combined medication is indicated for the treatment and prevention of specific types of headaches, namely vascular headaches such as migraines and cluster headaches. Ergotamine functions by constricting these dilated blood vessels, while caffeine enhances the absorption of ergotamine and further facilitates the constriction of widened blood vessels.

Uses and Dosage

Follow the instructions provided by your doctor when taking this medication orally, with or without food. Typically, at the initial sign of a headache, take 2 tablets, followed by 1 tablet every thirty minutes until the headache subsides.

Do not exceed 6 tablets per headache episode or 10 tablets within a seven-day period.

If your doctor has prescribed this medication for the prevention of specific headache types, such as cluster headaches, adhere strictly to their instructions, typically for a short-term treatment period of 2 to 3 weeks.

The dosage of this medication depends on your medical condition and response to treatment. Optimal results are achieved when the medication is taken promptly at the onset of a headache. Delaying the administration of the medication until the headache worsens may diminish its effectiveness.

In case you have a higher risk of heart problems, your doctor may conduct a heart examination prior to initiating the medication. They might advise you to take the initial dose under their supervision to monitor potential serious side effects, such as chest pain.

This medication is typically intended for occasional use and is not suitable for long-term daily usage.

While this medication provides relief to many individuals, it carries a potential risk of addiction. This risk may be elevated if you have a substance use disorder involving drugs or alcohol.

If you are utilizing medications for migraine attacks on 10 or more days per month, it is possible for the drugs to exacerbate your headaches (known as medication overuse headache). Refrain from using medications more frequently or for extended durations than directed. Inform your doctor if you require more frequent usage, if the medication’s effectiveness diminishes, or if your headaches worsen.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • nausea
  • vomiting

Inform your healthcare provider immediately if you experience any serious side effects:

  • leg weakness
  • chest pain
  • rapid heartbeat
  • slow heartbeat
  • dizziness
  • muscle pain in the legs or arms
  • blue hands and feet
  • swelling
  • itching
  • pain, burning, or tingling in the fingers and toes


Prior to initiating this medication, inform your doctor or pharmacist about any known allergies you may have, particularly to ergotamine, caffeine, other ergot alkaloids (such as dihydroergotamine), or any other substances. This product may contain inactive ingredients, such as tartrazine present in certain brands, which can potentially trigger allergic reactions or other complications.

Before using this medication, disclose your complete medical history to your doctor or pharmacist, especially if you have a history of blood circulation issues, specific types of headaches (hemiplegic or basilar migraines), heart problems, kidney disease, liver disease, personal or family history of substance use disorder involving drugs or alcohol, or a history of stroke or transient ischemic attack (commonly referred to as a “mini-stroke”).

Certain conditions may increase the risk of heart problems. Inform your doctor if you have any of these conditions, which include high blood pressure, high cholesterol, diabetes, family history of heart disease, being overweight, being postmenopausal (for women), or being over the age of 40 (for men).

This medication may cause dizziness. Consumption of alcohol or marijuana can intensify this dizziness. Refrain from driving, operating machinery, or engaging in activities requiring alertness until you can safely do so.

Using tobacco or nicotine products while taking this medication can heighten the risk of serious side effects, including heart problems and reduced blood flow to the brain, hands, and feet. Avoid tobacco use during the course of this medication. If you are a smoker, discuss smoking cessation methods with your doctor.

This medication must not be used during pregnancy as it can potentially harm an unborn baby. Consult your doctor regarding the use of reliable birth control methods, such as condoms or birth control pills. If you become pregnant or suspect you are pregnant, inform your doctor immediately.

This drug passes into breast milk and may have adverse effects on a nursing infant. Consult your doctor before breastfeeding while using this medication.

Form and Strength

Cafergot is available in the following forms and strengths:

  • Cafergot tablet:

    • 100/1mg


How long does it take for Cafergot to work?

Relief is often obtained within one-half hour of taking the medication.

Does Cafergot make you drowsy?

Cafergot doesn’t usually make people feel drowsy or sleepy, especially since it contains caffeine.



Additional information

Generic name:






Quantities Available:

30, 60, 90

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Cafergot (Caffeine/Ergotamine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Cafergot (Caffeine/Ergotamine).