Differin Gel (Adapalene) Customer Reviews

Differin Gel

Rx Prescription Required    RxFormulation : Gel

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Generic alternative for Differin Gel


Rx Prescription Required    RxFormulation : Gel

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Adapalene is indicated for the treatment of acne. Its administration may reduce the quantity and severity of acne pimples and facilitate faster healing of present lesions. This medication is classified as a retinoid medication, which exerts its therapeutic effect by modulating cellular growth and mitigating inflammatory processes, leading to a reduction in swelling.

Uses and Dosage

Administer this medication as directed by your physician or the product packaging, typically once per day at bedtime. Prior to application, delicately cleanse the affected area with a mild or soapless cleanser and dry it by patting.

If utilizing the gel, cream, or lotion, thoroughly wash your hands both before and after application. With your fingertips, apply a small quantity of the medication in a thin layer.

Only use this medication externally on the skin. Prevent contact with your eyes or lips, and do not apply to the inner lip area, inside the nose/mouth, cut, scraped, sunburned, or eczema-affected skin.

During the initial weeks of adapalene use, the acne might appear exacerbated due to the medication’s action on the pimples that are forming within the skin. It may take anywhere between 8 to 12 weeks to observe the medication’s effectiveness.

Use this medication regularly to derive the maximum benefits. To aid in recollection, use the medication at the same time each day. Do not increase the quantity or frequency of use beyond what is specified. Doing so will not expedite recovery but may instead increase the risk of adverse effects such as redness, peeling, or pain.

This medication is available in multiple forms and strengths such as gel, cream, and lotion. The selection of medication type best suited for you is dependent on the skin condition and treatment response. If there is no improvement or the condition worsens, inform your physician.

Since this medication can permeate through the skin and pose a risk to the unborn baby, women who are pregnant or may become pregnant should abstain from handling this medication.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • redness
  • scaling
  • dryness
  • burning or stinging
  • pain at the application site

Inform your healthcare provider immediately if you experience any serious side effects:

  • hives
  • itching
  • shortness of breath or difficulty breathing
  • swelling of the eyes, face, lips, tongue, or throat


Before using adapalene, inform your pharmacist or physician if you are hypersensitive to it, vitamin A-related drugs, or have any other allergies. This product may contain inactive constituents that can lead to allergic reactions or other complications.

Before using this medication, provide your physician or pharmacist with your medical history, particularly if you have eczema.

This medication might increase your skin’s sensitivity to sunlight. Minimize sun exposure, avoid tanning beds and sunlamps, and be cautious of weather extremes such as cold or windy conditions that may irritate the skin. Wear protective clothing and apply sunscreen daily when outside. If you develop sunburn or experience skin redness or blisters, alert your doctor immediately. Wait until your skin has entirely healed from a sunburn before resuming use of adapalene.

Avoid electrolysis, waxing, or using chemical depilatories for hair removal in areas where you have applied this medication.

As this drug is absorbed through the skin and could harm an unborn child, pregnant or potentially pregnant women should not handle this medication.

Notify your doctor if you are pregnant or plan to become pregnant. Adapalene should not be used while pregnant since it might be harmful to the fetus. If you become pregnant, seek medical advice from your doctor immediately.

It is unknown whether this drug is excreted into breast milk. Consult your doctor before breastfeeding.

Form and Strength

Differin Gel is available in the following forms and strengths:

  • Differin Gel gel:

    • 60g
  • adapalene gel:

    • 60g


How long does it take for Differin to work?

Full improvement should be seen within 12 weeks, especially if you use the medicine every day.

Does Differin reduce acne scars?

Differin can also help minimize scarring and improve skin texture.


  1. https://www.mayoclinic.org/drugs-supplements/adapalene-topical-route/proper-use/drg-20061544?p=1#:~:text=Full%20improvement%20should%20be%20seen,or%20other%20symptoms%20become%20severe
  2. https://www.healthline.com/health/beauty-skin-care/differn-gel-review#:~:text=In%202017%2C%20Differin%20Gel%20was,scarring%20and%20improve%20skin%20texture
  3. https://www.mayoclinic.org/drugs-supplements/adapalene-topical-route/proper-use/drg-20061544
  4. https://www.medbroadcast.com/drug/getdrug/differin
  5. https://www.webmd.com/drugs/2/drug-6445/differin-topical/details
  6. https://medlineplus.gov/druginfo/meds/a604001.html
  7. https://www.drugs.com/differin.html

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Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Differin Gel (Adapalene). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Differin Gel (Adapalene).