Durezol (Difluprednate Opthalmic Emulsion) Customer Reviews


Rx Prescription Required    RxFormulation : Ophthalmic Emulsion

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Generic alternative for Durezol

Difluprednate Opthalmic Emulsion

Rx Prescription Required    RxFormulation : Ophthalmic Emulsion

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Difluprednate ophthalmic solution is indicated for the treatment of ocular edema and pain following eye surgery. Belonging to the class of corticosteroid medications, difluprednate functions by inhibiting the release of specific endogenous substances that are responsible for inducing inflammation and discomfort.

Uses and Dosage

Difluprednate ophthalmic is administered as a liquid emulsion for application onto the eye. You should apply the medication to the affected eye(s) four times daily, commencing 24 hours after surgery, and continuing for a duration of two weeks. Subsequently, the frequency is reduced to twice daily for an additional week. The dosage may be gradually adjusted by your physician based on your individual condition and response to treatment.

To ensure optimal results, adhere to a consistent schedule when using difluprednate eye drops.Utilize difluprednate ophthalmic precisely as directed, avoiding excessive or insufficient use beyond the prescribed dosage determined by your doctor.

During the application of difluprednate eye drops, exercise caution to prevent the bottle’s tip from making contact with your eyes, fingers, face, or any other surfaces. Contamination of the eye drops with bacteria due to contact with foreign surfaces can lead to serious eye damage or vision loss. Should you suspect that your eye drops have become contaminated, promptly contact your doctor or pharmacist for further guidance.

To administer the eye drops, the following steps should be followed:

  1. Thoroughly wash hands with soap and water.
  2. Do not allow the dropper tip to touch the eye or any other surface, and ensure that it is kept clean.
  3. Tilt the head back and pull down the lower lid of the eye using the index finger to form a pocket.
  4. Hold the dropper as close to the eye as possible without making contact, and brace the remaining fingers against the face.
  5. Squeeze the dropper gently to instill a single drop in the pocket created by the lower eyelid while looking upwards.
  6. Remove the index finger from the lower eyelid and keep the eye closed for 2-3 minutes while tilting the head down.
  7. Apply gentle pressure to the tear duct using a finger.
  8. Use a tissue to wipe off any excess liquid from the face.
  9. Wash hands to remove any residual medication.

Side Effects

Inform your healthcare provider immediately if you experience any serious side effects:

  • blurred vision
  • decrease in vision
  • seeing a glare from lights or sun


Prior to using difluprednate, inform your doctor or pharmacist about any known allergies you may have, including allergies to the medication itself or other substances. This product may contain inactive ingredients that can trigger allergic reactions or other complications.

Before initiating treatment with this medication, disclose your medical history to your doctor or pharmacist, particularly if you have or have had any of the following conditions: current or previous eye infections, cataracts, or glaucoma.

After applying this medication, temporary blurred vision may occur. Refrain from driving, operating machinery, or engaging in activities that require clear vision until you can do so safely.

During pregnancy, the use of this medication should only be considered if absolutely necessary. Discuss the potential risks and benefits with your doctor before proceeding.

The passage of difluprednate into breast milk is currently unknown. Consult your doctor before breastfeeding while using this medication.

Form and Strength

Durezol is available in the following forms and strengths:

  • Durezol ophthalmic emulsion:

    • 0.05%
  • difluprednate opthalmic ophthalmic emulsion:

    • 0.05%


Can Durezol be used long term?

Durezol eye drops are not for long-term use. Steroid eye drops may cause glaucoma or posterior subcapsular cataracts if used too long.

Is Durezol an antibiotic?

No, Durezol isn’t an antibiotic eye drop.


  1. https://www.goodrx.com/durezol/what-is#faqs
  2. https://www.mayoclinic.org/drugs-supplements/difluprednate-ophthalmic-route/side-effects/drg-20072011?p=1
  3. https://www.webmd.com/drugs/2/drug-151208/durezol-ophthalmic-eye/details
  4. https://medlineplus.gov/druginfo/meds/a609025.html
  5. https://www.drugs.com/durezol.html

Additional information

Generic name:

Difluprednate Opthalmic Emulsion


Ophthalmic Emulsion



Quantities Available:

5mL, 10mL

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Durezol (Difluprednate Opthalmic Emulsion). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Durezol (Difluprednate Opthalmic Emulsion).