Edarbyclor (Azilsartan Medoxomil/Chlorthalidone) Customer Reviews


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Generic alternative for Edarbyclor

Azilsartan Medoxomil/Chlorthalidone

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This combination product contains the active ingredients azilsartan and chlorthalidone. Azilsartan falls within the category of medications known as angiotensin II receptor blockers (ARBs), while chlorthalidone belongs to the class of diuretics, commonly referred to as water pills. These medications operate within the kidney to effectively mitigate severe cases of hypertension, thereby reducing elevated blood pressure levels. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

Uses and Dosage

Follow your doctor’s instructions and take this medication orally, with or without food, usually once a day. Avoid taking this drug close to bedtime to minimize the need to wake up for urination during the night. Administer the medication at least 4 hours before your intended bedtime.

The prescribed dosage is determined based on your medical condition and response to treatment.

Consistently take this medication to derive maximum benefits. Establish a routine by taking it at the same time every day to aid in remembering. Continue taking the medication even if you feel well, as individuals with high blood pressure often do not experience noticeable symptoms.

It may take several weeks before the full therapeutic effects of this medication are observed.

If you are also taking certain medications to lower cholesterol levels (such as bile acid-binding resins like cholestyramine or colestipol), ensure that you take azilsartan/chlorthalidone at least 2 hours before or 4 hours after these medications.

Inform your doctor if your condition does not improve or worsens, such as if your blood pressure readings remain high or increase.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • abdominal pain or discomfort
  • back or leg pain
  • constipation
  • decreased appetite
  • decreased ability or interest in sexual activity
  • diarrhea
  • difficulty sleeping
  • dizziness
  • drowsiness
  • dry mouth
  • fatigue
  • headache

Inform your healthcare provider immediately if you experience any serious side effects:

  • increased heart rate or irregular heart beat
  • pins and needles feeling in your fingers
  • pale skin
  • unusual tiredness or weakness
  • fever or chills
  • severe diarrhea
  • shortness of breath
  • swelling of the hands and feet, puffiness from fluid retention
  • swollen glands in the mouth and neck


Prior to initiating this medication, inform your healthcare provider or pharmacist about any known allergies to azilsartan or chlorthalidone, as well as any other allergies you may have. This product may contain inactive ingredients that could potentially elicit allergic reactions or other complications.

Before using this medication, disclose your medical history to your doctor or pharmacist, especially if you have a history of kidney disease, liver disease, dehydration, untreated mineral imbalances, gout, or lupus.

This drug may cause dizziness. The consumption of alcohol or marijuana can further increase dizziness. Refrain from activities that require alertness, such as driving or operating machinery, until you can safely do so.

The risk of lightheadedness or dehydration may increase in cases of severe sweating, diarrhea, or vomiting. Notify your doctor if you experience prolonged episodes of diarrhea or vomiting. To prevent dehydration, ensure an adequate fluid intake unless directed otherwise by your doctor.

For individuals with diabetes, this product may impact blood sugar levels. Monitor your blood sugar regularly as instructed and share the results with your doctor. Adjustments to your diabetes medication, exercise regimen, or diet may be necessary.

This product can affect potassium levels in your body. Consult your doctor or pharmacist before using potassium supplements or salt substitutes that contain potassium.

This medication may heighten your sensitivity to the sun. Limit your sun exposure, avoid tanning booths and sunlamps, and use sunscreen and protective clothing when outdoors. Promptly inform your doctor in case of sunburn or skin blisters/redness.

Elderly individuals may be more susceptible to the side effects of this medication, particularly dizziness and changes in urinary output (indicative of kidney problems).

Inform your doctor if you are pregnant or planning to conceive. You should not become pregnant while using this medication, as it may pose risks to the unborn baby. In the event of pregnancy, promptly consult your doctor to assess the potential risks and benefits associated with this medication.

The passage of azilsartan into breast milk is unknown, while chlorthalidone does pass into breast milk. Consult your doctor before breastfeeding.

Form and Strength

Edarbyclor is available in the following forms and strengths:

  • Edarbyclor tablet:

    • 40/12.5mg
    • 40/25mg
  • azilsartan and chlorthalidone tablet:

    • 40/12.5mg


How quickly does Edarbyclor lower blood pressure?

A reduction in your blood pressure will be measureable within 2 weeks of initiation of treatment and the full effect of your dose will be observed by 4 weeks.

Can Edarbyclor cause skin damage?

Not directly, but Edarbyclor can make your skin more sensitive to light. Avoid spending long periods of time in the sun.


  1. https://www.goodrx.com/edarbyclor/what-is#faqs
  2. https://www.mayoclinic.org/drugs-supplements/azilsartan-and-chlorthalidone-oral-route/before-using/drg-20075383?p=1
  3. https://www.webmd.com/drugs/2/drug-159144/edarbyclor-oral/details
  4. https://www.medbroadcast.com/drug/getdrug/edarbyclor#adverseeffects
  5. https://www.drugs.com/edarbyclor.html

Additional information

Generic name:

Azilsartan Medoxomil/Chlorthalidone




40/12.5mg, 40/25mg

Quantities Available:

84, 100

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Edarbyclor (Azilsartan Medoxomil/Chlorthalidone). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Edarbyclor (Azilsartan Medoxomil/Chlorthalidone).