Prescription Required 
Formulation : 
Description
Indications
Epinephrine injection is combined with emergency medical care to address severe allergic reactions triggered by insect bites or stings, foods, medications, latex, and various other sources. It is also employed in treating life-threatening low blood pressure associated with septic shock in hospitalized adults. Epinephrine belongs to a group of medications known as alpha- and beta-adrenergic agonists, or sympathomimetic agents. Its mechanism involves relaxing the airway muscles while constricting blood vessels.
Uses and Dosage
Epinephrine injection is available in two forms: as a prefilled automatic injection device and in vials for subcutaneous or intramuscular injection. It is primarily used to address life-threatening allergic reactions. Typically, it is administered at the first indication of such a reaction. In cases of life-threatening low blood pressure due to septic shock, medical professionals usually administer it intravenously.
Your doctor or pharmacist can demonstrate how to use the prefilled automatic injection device, and training devices are available for practice.
Administer epinephrine injection promptly upon suspecting a severe allergic reaction. Familiarize yourself with the signs of such a reaction, and ensure you understand when to administer the injection.
You should carry or have access to at least two automatic injection devices at all times, as one dose may not be adequate. Regularly check the expiration date and inspect the solution for discoloration or particles.
Most devices contain a single dose of epinephrine. If symptoms persist or recur, a second dose may be necessary as directed by your doctor. Medical professionals should handle administration beyond two injections per allergic episode.
While epinephrine injection is crucial for managing severe allergic reactions, it does not replace the need for emergency medical care. Seek immediate medical attention after administering epinephrine and rest until help arrives.
When administering epinephrine, inject it into the middle of the outer thigh. In emergencies, injection through clothing is acceptable. For children who may move during injection, secure their leg and limit movement. Avoid injecting into other body parts or veins, and if accidental injection occurs, seek emergency medical assistance.
After administration, some solution may remain in the device, which is normal. Dispose of the used device properly and inquire with medical professionals about safe disposal methods.
Side Effects
Inform your healthcare provider immediately if you experience any serious side effects:
- skin redness, swelling, warmth, or tenderness at the site of injection
- difficulty breathing
- pounding, fast, or irregular heartbeat
- nausea
- vomiting
- sweating
- dizziness
- nervousness, anxiety, or restlessness
- weakness
- pale skin
- headache
- uncontrollable shaking of a part of your body
Caution
- Before using this medication, inform your doctor or pharmacist about any allergies you have, as well as your medical history. This product may contain inactive ingredients that could trigger allergic reactions or other complications.
- This product may contain sulfites. However, even if you have a sulfite allergy, you should this medication during emergencies. The potential life-saving benefits of epinephrine outweigh any risks associated with sulfite-related issues.
- Prior to using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of heart problems (such as angina or irregular heartbeat), high blood pressure, thyroid disorders, or diabetes.
- This medication may cause dizziness. Consumption of alcohol or marijuana (cannabis) may exacerbate this effect. Refrain from driving, operating machinery, or engaging in activities requiring alertness until you can do so safely.
- Older adults may be more susceptible to the side effects of this medication, particularly a rapid increase in blood pressure.
- If you are pregnant, you can use this drug in the same manner as if you were not pregnant.
- While it is uncertain whether this medication passes into breast milk, it is unlikely to harm a nursing infant. Consult your doctor before breastfeeding.
Form and Strength
Emerade Auto Injector is available in the following forms and strengths:
- Emerade Auto Injector autoinjector:
- 0.15 mg
- 0.3 mg
FAQ
Is Emerade Auto Injector a hormone?
Yes, Emerade Auto Injector (also called the hormone adrenaline) is a hormone that’s normally made in your adrenal glands.
The overall purpose of epinephrine is to prepare your body for the “fight-or-flight” response to stress. It does this by raising your heart rate and blood pressure and opening your airways to make it easier to breathe.
How long does Emerade Auto Injector last?
Emerade Auto Injector works very quickly to relieve symptoms of a serious allergic reaction. But its effects don’t last very long. Remember to get medical help right away after you use Emerade Auto Injector.
Resources
- https://www.goodrx.com/epinephrine-epipen/what-is#faqs
- https://www.mayoclinic.org/drugs-supplements/epinephrine-injection-route/side-effects/drg-20072429
- https://medlineplus.gov/druginfo/meds/a603002.html
- https://www.webmd.com/drugs/2/drug-76758/epinephrine-injection/details
- https://www.drugs.com/mtm/adrenalin.html
