Evalon Cream (Estriol) Customer Reviews

Evalon Cream

Rx Prescription Required    RxFormulation : Cream

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Estriol is prescribed for the management of various symptoms experienced by women during or after menopause, including vaginal dryness, itching, and burning. Estriol belongs to a class of medications known as hormones and functions by replenishing the body’s natural estrogen production.

Uses and Dosage

Adhere to the instructions provided by your healthcare professional when using this medication. Prepare the applicator by filling it with the prescribed medication as directed. Gently insert the applicator deep into the vagina and press the plunger to release the medication. After use, clean the applicator using warm soapy water, ensuring a thorough rinse.

Avoid boiling or using hot water to clean the applicator.

The dosage of this medication will be determined based on your specific medical condition and your response to the treatment.

Consistently use this medication as directed to obtain the maximum benefits. Carefully follow your prescribed dosing schedule and refrain from increasing the dosage or using the medication more frequently or for a longer duration than instructed.

If your condition fails to improve or worsens, inform your doctor.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • breast pain or tenderness
  • nausea
  • headache
  • vomiting
  • diarrhea
  • difficulty falling asleep or staying asleep
  • changes in sexual desire
  • hair loss
  • spotty darkening of the skin on the face
  • sudden feelings of heat or sweating
  • stomach pain or bloating
  • swelling, redness, burning, itching, or irritation of the vagina
  • vaginal discharge
  • painful or difficult urination
  • back or joint pain
  • runny nose or congestion

Inform your healthcare provider immediately if you experience any serious side effects:

  • bulging eyes
  • ongoing pain that begins in the stomach area but may spread to the back nausea, vomiting, or loss of appetite
  • rash, hives, itching, hoarseness, or difficulty breathing or swallowing
  • swelling of the eyes, face, tongue, throat, hands, arms, feet, ankles, or lower legs
  • fever
  • nausea or vomiting
  • diarrhea
  • muscle pain
  • dizziness or fainting
  • rash on face or body


  • Prior to initiating this medication, inform your healthcare provider or pharmacist about any known allergies you may have, including allergies to this specific medication or other substances. This product may contain inactive ingredients that could potentially trigger allergic reactions or other complications.
  • Before using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of vaginal bleeding of unknown cause, certain types of cancers, blood clotting disorders, stroke, heart disease, liver disease, kidney disease, a family history of specific medical conditions (such as breast lumps, cancer, or blood clots), a personal or family history of a swelling disorder called angioedema, blood clotting disorders, high blood pressure, diabetes, high levels of cholesterol or triglycerides, obesity, lupus, underactive thyroid (hypothyroidism), mineral imbalances, a particular hormone problem known as hypoparathyroidism, uterine problems, gallbladder disease, asthma, seizures, migraine headaches, mental or mood disorders, or certain blood disorders (porphyria).
  • Refrain from smoking or using tobacco products while taking this medication. The combination of estrogens and smoking significantly increases the risk of stroke, blood clots, high blood pressure, and heart attacks, particularly in women above the age of 35.
  • Notify your doctor if you have recently undergone or will be undergoing surgery, or if you anticipate prolonged periods of immobilization (such as during a long plane flight). These circumstances heighten the risk of developing blood clots, especially when using estrogen products. Your doctor may recommend temporarily discontinuing this medication or taking additional precautions.
  • This medication may induce the appearance of blotchy and dark areas on the face and skin, a condition known as melasma. Sun exposure can exacerbate this effect. Minimize your time in the sun, avoid tanning beds and sunlamps, and utilize sunscreen and protective clothing when outdoors.
  • Individuals who are nearsighted or wear contact lenses may experience vision problems or difficulties with contact lens wear while using this medication. Should these issues arise, promptly contact your eye doctor.
  • Certain estrogen products contain mineral oil, which can weaken latex condoms, cervical caps, and diaphragms, potentially leading to their ineffectiveness. If you are uncertain whether your product contains mineral oil, consult your pharmacist. If mineral oil is present, discuss alternative birth control methods with your doctor while using this medication.
  • This medication should not be used during pregnancy. If you become pregnant or suspect that you may be pregnant, inform your doctor.
  • This medication passes into breast milk and may reduce the quantity and quality of breast milk produced. Prior to breastfeeding, consult your doctor for guidance.

Form and Strength

Evalon Cream is available in the following forms and strengths:

  • Evalon Cream cream:
    • 1 mg


How long does Evalon Cream take to work?

Topical estrogen can take 3 to 4 weeks to reach its maximum effect.

What should I avoid while taking Evalon Cream?

Patients should not smoke when using Evalon Cream. Smoking increases your chances of having blood clots or strokes.


  1. https://www.goodrx.com/estrace/what-is
  2. https://www.1mg.com/drugs/evalon-cream-117524
  3. https://go.drugbank.com/drugs/DB04573
  4. https://my.clevelandclinic.org/health/articles/22399-estriol
  5. https://www.practo.com/medicine-info/evalon-cream-53492

Additional information

Generic name:






Quantities Available:

15g, 50g

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Evalon Cream (Estriol). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Evalon Cream (Estriol).