Hygroton (Chlorthalidone) Customer Reviews


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Chlorthalidone is utilized in the management of high blood pressure, medically known as hypertension. This medication plays a crucial role in lowering elevated blood pressure, thereby reducing the risk of strokes, heart attacks, and kidney complications. It also serves the purpose of mitigating excessive salt and water retention in the body, which may be caused by underlying conditions like heart failure, liver disease, or kidney disease.

By decreasing the accumulation of surplus salt and water in the body, chlorthalidone aids in alleviating edema (swelling) and respiratory difficulties that may arise due to fluid accumulation in the lungs. Classified as a diuretic or “water pill,” chlorthalidone enhances urine production, particularly during the initial stages of treatment.

Uses and Dosage

Chlorthalidone is available in tablet form for oral administration. Typically, it is taken once daily or every other day, preferably after a meal, particularly breakfast. Morning administration is recommended to minimize the need for nighttime bathroom visits.

To ensure proper usage, carefully adhere to the instructions provided on your prescription label. Take chlorthalidone exactly as prescribed, without altering the dosage or frequency, following your doctor’s instructions diligently.

While chlorthalidone effectively manages high blood pressure, it is not a curative treatment. Continue taking the medication even if you start feeling better. Abruptly discontinuing chlorthalidone should only be done under the guidance and approval of your healthcare provider.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • muscle weakness
  • dizziness
  • cramps
  • thirst
  • stomach pain
  • upset stomach
  • vomiting
  • diarrhea
  • loss of appetite
  • headache
  • hair loss

Inform your healthcare provider immediately if you experience any serious side effects:

  • sore throat with fever
  • unusual bleeding or bruising
  • severe skin rash with peeling skin
  • difficulty breathing or swallowing


Prior to commencing chlorthalidone treatment, inform your doctor or pharmacist about any known allergies, including an allergic reaction to chlorthalidone itself or any other substances present in the product. Certain inactive ingredients may be present, which could trigger allergic reactions or other complications.

Before using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of kidney disease, liver disease, gout, lupus, or untreated mineral imbalances, such as low potassium levels.

This drug may cause dizziness, which can be exacerbated by the consumption of alcohol or marijuana. Refrain from driving, operating machinery, or engaging in activities that require alertness until you are confident in your ability to do so safely.

Excessive sweating, diarrhea, or vomiting can lead to dehydration, increasing the risk of dizziness or lightheadedness. Report any prolonged episodes of diarrhea or vomiting to your doctor. Unless otherwise directed by your doctor, ensure an adequate intake of fluids to prevent dehydration.

If you have diabetes, be aware that this medication may influence your blood sugar levels. Monitor your blood sugar regularly as prescribed and share the results with your doctor. If you experience symptoms of high blood sugar, such as increased thirst or urination, promptly inform your doctor. Your diabetes medication, exercise regimen, or diet may need adjustment.

Chlorthalidone may reduce potassium levels in the blood. Discuss the possibility of adding potassium to your diet with your doctor, who may prescribe a potassium supplement.

Be cautious of increased sun sensitivity while using this medication. Minimize sun exposure, avoid tanning booths and sunlamps, and wear protective clothing and sunscreen when outdoors. In case of sunburn or skin blisters/redness, promptly notify your doctor.

Older adults may be more susceptible to the side effects of this medication, particularly dizziness.

During pregnancy, use this medication only when the benefits clearly outweigh the risks. Engage in a thorough discussion with your doctor regarding the potential risks and benefits.

If you are breastfeeding, consult your doctor before initiating chlorthalidone treatment, as this medication passes into breast milk. Your doctor can provide guidance on whether it is safe to breastfeed while using this medication.

Form and Strength

Hygroton is available in the following forms and strengths:

  • chlorthalidone tablet:

    • 50mg


What is the best time of day to take Hygroton?

It is best to avoid taking this medication within 4 hours of your bedtime to avoid having to get up to urinate.

How long does Hygroton take to work?

The diuretic effect (more urination) will usually start within about 2-3 hours after taking your dose and continue for up to 3 days.


  1. https://www.goodrx.com/chlorthalidone/what-is#faqs
  2. https://www.mayoclinic.org/drugs-supplements/chlorthalidone-oral-route/description/drg-20071817
  3. https://www.webmd.com/drugs/2/drug-6831/hygroton-oral/details
  4. https://medlineplus.gov/druginfo/meds/a682342.html
  5. https://www.drugs.com/sfx/hygroton-side-effects.html

Additional information

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Quantities Available:

100, 200

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Hygroton (Chlorthalidone). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Hygroton (Chlorthalidone).