Inspra (Eplerenone) Customer Reviews


Rx Prescription Required    RxFormulation : Tablet

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Generic alternative for Inspra


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Eplerenone is indicated for monotherapy or adjunctive therapy in the management of hypertension. Classified as a mineralocorticoid receptor antagonist, eplerenone functions by inhibiting the action of aldosterone, an endogenous substance responsible for elevating blood pressure within the body.

Uses and Dosage

Eplerenone is administered in tablet form for oral consumption. The typical dosing regimen involves taking it once or twice daily, with or without food.

To ensure consistency, take the medication at approximately the same time each day. Adherence to the prescribed instructions is crucial, carefully follow the guidance provided on the prescription label.

Take eplerenone precisely as directed, avoiding any deviation from the prescribed dosage, either in excess or deficiency, and refraining from altering the frequency beyond the physician’s recommendations.

Initiation of eplerenone treatment may begin with a low dose, with the possibility of dose adjustments after a 4-week period.

While eplerenone effectively manages high blood pressure, it should be noted that it is not curative. The full therapeutic effects may take up to 4 weeks or longer to manifest. Throughout this period, remain consistent in taking eplerenone, even if you experience an improvement in symptoms. Abruptly discontinuing the medication should be avoided, and any decisions regarding its usage should be discussed with your doctor.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • headache
  • dizziness
  • diarrhea
  • stomach pain
  • cough
  • excessive tiredness
  • flu-like symptoms
  • breast enlargement or tenderness
  • abnormal vaginal bleeding

Inform your healthcare provider immediately if you experience any serious side effects:

  • chest pain
  • tingling in arms and legs
  • loss of muscle tone
  • weakness or heaviness in legs
  • confusion
  • lack of energy
  • cold, gray skin
  • irregular heartbeat


Prior to initiating eplerenone therapy, inform your healthcare provider or pharmacist about any known allergies, including allergies to eplerenone itself, and any other allergies you may have. This medication may contain inactive ingredients that could trigger allergic reactions or other adverse effects.

Before commencing treatment with this medication, discuss your medical history with your doctor or pharmacist, particularly if you have a history of conditions such as high blood potassium levels (hyperkalemia), kidney disease, or diabetes.

Eplerenone may lead to an increase in potassium levels in the body. Consult your doctor or pharmacist before using potassium supplements or salt substitutes that contain potassium.

The use of this drug may result in dizziness. Be cautious when using alcohol or marijuana, as they can exacerbate dizziness. Refrain from activities that require alertness, such as driving or operating machinery, until you can do so safely.

Elderly individuals may exhibit increased sensitivity to this medication, especially concerning elevated blood potassium levels.

During pregnancy, eplerenone should only be used when the potential benefits clearly outweigh the risks. Discuss the risks and benefits of the medication with your doctor before using it during pregnancy.

Regarding breast-feeding, it is uncertain whether this drug passes into breast milk. Consult your doctor before breast-feeding while taking eplerenone.

Form and Strength

Inspra is available in the following forms and strengths:

  • Inspra tablet:

    • 25mg
    • 50mg
  • eplerenone tablet:

    • 25mg
    • 50mg


What kind of diuretic is Inspra?

Inspra is a potassium-sparing diuretic similar to spironolactone, selectively blocks aldosterone to lower blood pressure.

Does Inspra increase urination?

Yes, Inspra is a diuretic. Diuretics are a class of drugs that lowers the excess water and salt in the body by causing excess urination.



Additional information

Generic name:



Film Coated Tablet, Tablet


25mg, 50mg

Quantities Available:

84, 90, 100

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Inspra (Eplerenone). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Inspra (Eplerenone).