Levoxyl (Levothyroxine) Customer Reviews


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Levothyroxine is a medication that is utilized in the treatment of hypothyroidism, a condition characterized by an underactive thyroid. This drug functions by replacing or supplementing the thyroid hormone that is typically generated by the thyroid gland. Low levels of thyroid hormone may occur naturally, as well as due to injury caused by radiation, medications, or surgical removal of the thyroid gland.

Sufficient levels of thyroid hormone are necessary for maintaining normal physical and mental activity in individuals, and in children, it is critical for healthy physical and cognitive development. In addition to its use in hypothyroidism, this medication is also employed in the treatment of other thyroid disorders, such as thyroid cancer.

Uses and Dosage

Administration of this medication should be in accordance with your doctor’s instructions. It is usually taken orally once a day, on an empty stomach, 30 minutes to 1 hour before breakfast. Unless otherwise directed by your physician, take the medication with a full glass of water.

If the capsule form of this medication is being taken, it should be swallowed whole, without splitting, crushing, or chewing.

For individuals who are unable to swallow the capsule, the tablet form of the medication should be used. In such cases, crush the tablet and mix it in 1 to 2 teaspoons (5 to 10 milliliters) of water. Administer the mixture immediately using a dropper or spoon. Do not prepare a supply in advance.

The dosage of this medication depends on various factors including age, weight, medical condition, laboratory test results, response to treatment, and other medications being taken. Be sure to inform your doctor and pharmacist of all products you use, including prescription drugs, non-prescription drugs, and herbal products.

In order to achieve optimal results, use this medication regularly. To help you remember, take it at the same time every day. Do not discontinue this medication without consulting your doctor first. Thyroid replacement therapy is usually required for the entirety of one’s life.

Different brands of levothyroxine are available. Do not switch brands without first consulting your doctor or pharmacist.

Several medications, including cholestyramine, colestipol, colesevelam, antacids, sucralfate, simethicone, iron, sodium polystyrene sulfonate, calcium supplements, orlistat, lanthanum, sevelamer, among others, may decrease the amount of thyroid hormone absorbed by your body. If you are taking any of these drugs, take them at least 4 hours apart from levothyroxine.

Symptoms of low thyroid hormone levels include muscle aches, tiredness, constipation, dry skin, weight gain, slow heartbeat, or sensitivity to cold. If your condition worsens or persists after several weeks of taking this medication, inform your doctor.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • weight gain or loss
  • headache
  • vomiting
  • diarrhea
  • changes in appetite
  • changes in menstrual cycle
  • sensitivity to heat
  • hair loss
  • joint pain
  • leg cramps

Inform your healthcare provider immediately if you experience any serious side effects:

  • chest pain, discomfort, or tightness
  • decreased urine output
  • difficult or labored breathing
  • difficulty with swallowing
  • dilated neck veins
  • extreme fatigue
  • fainting
  • fast, slow, irregular, pounding, or racing heartbeat or pulse
  • fever
  • heat intolerance
  • hives or welts, skin itching, rash, or redness
  • irregular breathing
  • irritability
  • menstrual changes
  • nausea
  • pain or discomfort in the arms, jaw, back, or neck
  • sweating
  • swelling of the eyes, face, lips, throat, or tongue
  • tremors


Prior to taking levothyroxine, inform your physician or pharmacist about any known allergies or allergic reactions to this medication or other substances. Inactive ingredients present in this medication may also result in allergic reactions or other complications.

Prior to using this medication, share your medical history with your physician or pharmacist, especially if you have any of the following: overactive thyroid, reduced adrenal gland function, heart disease, high blood pressure, or diabetes.

If you have diabetes, levothyroxine may impact your blood sugar levels. Monitor your blood sugar regularly and share your results with your physician. If you experience increased thirst, urination, shakiness, unusual sweating, dizziness, or hunger, contact your physician immediately. Your physician may need to adjust your diabetes medication, exercise program, or diet.

Children may be more vulnerable to specific side effects of this medication, such as headache, vision changes, and hip or leg pain. Elevated thyroid hormone levels can impede bone development and growth, resulting in reduced adult height. Ensure that all medical appointments and lab tests are kept so that the doctor can monitor treatment.

Older adults may be more susceptible to the side effects of this medication, especially fast, pounding, or irregular heartbeat.

This medication may be administered during pregnancy. Inform your physician if you are pregnant since your dose may need to be adjusted.

Levothyroxine passes into breast milk, but it is unlikely to harm a nursing infant. Before breast-feeding, consult your physician.

Form and Strength

Levoxyl is available in the following forms and strengths:

  • Levoxyl tablet:

    • 0.05mg
    • 0.10mg
    • 0.15mg


How is Levoxyl different from Synthroid?

Levoxyl and Synthroid contain the same active ingredient, levothyroxine, but they contain different inactive ingredients.

Is weight gain a side effect of Levoxyl?

Both weight gain and weight loss are possible side effects.


  1. https://www.drugs.com/medical-answers/difference-between-levoxyl-synthroid-3562495/#:~:text=by%20Drugs.com,Calcium%20sulfate%20dihydrate
  2. https://www.endocrineweb.com/conditions/hypothyroidism/levothyroxine-weight-gain
  3. https://medlineplus.gov/druginfo/meds/a682461.html
  4. https://www.webmd.com/drugs/2/drug-6137/levoxyl-oral/details
  5. https://www.mayoclinic.org/drugs-supplements/levothyroxine-oral-route/side-effects/drg-20072133?p=1
  6. https://www.drugs.com/levoxyl.html

Additional information

Generic name:





0.05mg, 0.100mg, 0.150mg

Quantities Available:


Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Levoxyl (Levothyroxine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Levoxyl (Levothyroxine).