Lutrepulse (Gonadorelin)

Description

Indications

Gonadorelin is prescribed to women experiencing absent menstrual periods due to low levels of gonadotropin-releasing hormone (GnRH). It is often utilized as a component of female infertility treatment. This medication supplies the necessary GnRH to stimulate the growth and release of mature eggs from the ovaries, a process known as ovulation.

Uses and Dosage

Gonadorelin is administered either intravenously or subcutaneously using an infusion pump, following your doctor’s instructions. If you’re self-administering at home, thoroughly understand the preparation and usage guidelines provided by your healthcare professional and the medication package. Adhere to all instructions for using the infusion pump.

Only mix the medication when you’re prepared to use it. Prior to administration, visually inspect the solution for particles or discoloration. Do not use the solution if either is present.

Before each dose, cleanse the injection site with rubbing alcohol. If injecting under the skin, rotate injection sites as instructed by your doctor to minimize skin injury. If administering into a vein, changing the injection site isn’t necessary unless directed otherwise by your doctor.

Dosage is determined by your medical condition and response to treatment. Attend all medical appointments to allow your doctor to monitor your response closely and adjust your dosage if needed. Do not alter the dose unless instructed by your doctor, and avoid using the medication for a longer duration than prescribed.

Learn proper storage and disposal methods for medical supplies to ensure safety.

Inform your doctor if your condition does not improve.

Side Effects

Some side effects may occur that usually do not need medical attention:

• abdominal or stomach discomfort
• flushing (lasting only a short time)
• headaches
• lightheadedness
• nausea

Inform your healthcare provider immediately if you experience any serious side effects:

• difficulty in breathing
• flushing (continuing)
• rapid heartbeat
• hardening of skin at place of injection
• hives
• itching, pain, redness or swelling of skin at place of injection
• skin rash (at place of injection or over entire body)

Caution

• Before using gonadorelin, inform your doctor or pharmacist about any allergies you have, as this product may contain inactive ingredients that could cause allergic reactions or other complications. Discuss any concerns with your pharmacist for further details.
• Before using this medication, disclose your medical history to your doctor or pharmacist, especially if you have ovarian cysts, kidney disease, tumors of the pituitary gland, cancer of the reproductive organs, or mental/mood problems like depression.
• The use of gonadorelin may increase the likelihood of multiple births, such as twins or triplets. It’s essential to discuss the risks and benefits of such a pregnancy with your doctor.
• This medication may be utilized during the first trimester of pregnancy under the direction of your doctor. Notify your doctor immediately if you become pregnant or suspect you may be pregnant. Consult your doctor for more information.
• It’s unclear whether gonadorelin passes into breast milk. Generally, this medication is not recommended for nursing women. Consult your doctor before breastfeeding to discuss potential risks and benefits.

Form and Strength

Lutrepulse is available in the following forms and strengths:

• Lutrepulse vial:
  • 0.8 mg

FAQ

Can I self-administer Lutrepulse?

It is generally recommended to administer Lutrepulse in a clinical setting, by a trained medical professional.

Does Lutrepulse cause weight gain?

Weight gain is a rare but possible side effect of this medication.

Resources

1. https://www.mayoclinic.org/drugs-supplements/gonadorelin-intravenous-route-injection-route/description/drg-20067426
2. https://www.medbroadcast.com/drug/getdrug/lutrepulse#adverseeffects
3. https://www.healthlinkbc.ca/medications/gonadorelin-injection
4. https://www.webmd.com/drugs/2/drug-4210/gonadorelin-injection/details
5. https://www.drugs.com/mtm/gonadorelin-injectable.html