Maxzide (Triamterene/Hctz) Customer Reviews


Rx Prescription Required    RxFormulation : Tablet

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The combination of triamterene and hydrochlorothiazide is indicated for the management of hypertension and edema in patients presenting with hypokalemia or those at risk of hazardous potassium depletion. Classified as diuretics, this medication duo operates by facilitating renal excretion of surplus water and sodium, thereby promoting a reduction in fluid retention within the body.

Uses and Dosage

Triamterene and hydrochlorothiazide are available in capsule and tablet forms for oral administration. Typically, it is taken once daily at a consistent time.

Strictly follow the prescribed dosage without exceeding or reducing it, and avoid taking it more frequently than advised by your doctor.

While this medication effectively manages high blood pressure and edema, it does not offer a cure for these conditions. Continue taking triamterene and hydrochlorothiazide even if you feel well. Discontinuing the medication should only be done under the guidance of your doctor.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • frequent urination
  • headache

Inform your healthcare provider immediately if you experience any serious side effects:

  • rash
  • hives
  • itching
  • difficulty breathing or swallowing
  • pain in the upper stomach area
  • swelling or tenderness of stomach area
  • upset stomach
  • fever
  • unusual bruising or bleeding
  • loss of appetite
  • yellowing of skin or eyes
  • flu-like symptoms
  • feelings of numbness, tingling, pricking, burning, or creeping on the skin
  • inability to move arms and legs
  • slow or irregular heartbeat


Prior to initiating this medication, inform your healthcare provider or pharmacist about any known allergies to triamterene or hydrochlorothiazide, or any other allergens. This product may contain inactive components that could trigger allergic reactions or other adverse effects.

Before using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have diabetes, gout, high blood potassium levels, kidney disease, liver disease, lupus, or a history of skin cancer.

This drug may cause dizziness. Consumption of alcohol or marijuana may exacerbate dizziness. Avoid driving, operating machinery, or engaging in activities requiring alertness until you can do so safely.

Increased risk of lightheadedness or dehydration may arise from severe sweating, diarrhea, or vomiting. Report prolonged instances of diarrhea or vomiting to your doctor. To prevent dehydration, maintain adequate fluid intake unless otherwise advised by your doctor.

If you have diabetes, this product may impact your blood sugar levels. Monitor your blood sugar regularly as directed and share the results with your doctor. Your diabetes medication, exercise regimen, or diet may require adjustments.

This medication can affect potassium levels in your body. Prior to using potassium supplements or salt substitutes containing potassium, consult your doctor or pharmacist.

Exposure to the sun may lead to increased sensitivity, and prolonged use of this medication may heighten the risk of skin cancer. Limit sun exposure, avoid tanning booths and sunlamps, and use sunscreen and protective clothing while outdoors. Inform your doctor promptly if you experience sunburn, skin blisters/redness, or observe new or changed moles/skin lesions.

Elderly individuals may exhibit increased sensitivity to this drug, particularly regarding dizziness or high blood potassium levels.

During pregnancy, use this medication only if clearly necessary, as it may pose risks to an unborn baby. Discuss the potential benefits and risks with your doctor.

It is uncertain if triamterene passes into breast milk, but hydrochlorothiazide is likely to be present. Consult your doctor before breastfeeding.

Form and Strength

Maxzide is available in the following forms and strengths:

  • triamterene and hydrochlorothiazide tablet:

    • 75mg
    • 50mg


How long does it take for Maxzide to work?

You’ll notice a need to urinate more often starting a couple of hours after taking Maxzide. This effect can last anywhere from 6 to 12 hours, so make sure you have reliable access to a bathroom after your dose.

When should I take Maxzide?

Because Maxzide contains 2 diuretics (water pills), it’s usually better to take your dose early during the day to avoid waking up in the middle of the night to use the bathroom.



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Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Maxzide (Triamterene/Hctz). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Maxzide (Triamterene/Hctz).