Prescription Required 
Formulation : 
Description
Indications
Ketoprofen serves to alleviate pain stemming from diverse conditions like dental pain, menstrual cramps, and muscle aches.
Additionally, it aids in reducing pain, swelling, and joint stiffness associated with arthritis. Classified as a nonsteroidal anti-inflammatory drug (NSAID), ketoprofen functions by inhibiting the body’s production of specific natural substances responsible for inflammation. This action leads to a reduction in swelling, pain, or fever.
Uses and Dosage
Prescription ketoprofen is available in capsule and extended-release (long-acting) capsule forms for oral administration.
Typically, capsules are taken three or four times daily for arthritis or every 6 to 8 hours as needed for pain. Extended-release capsules are generally taken once daily. If taken regularly, ensure to take ketoprofen at consistent times each day.
Nonprescription ketoprofen is in tablet form for oral consumption. It’s usually ingested with a full glass of water or another liquid every 4 to 6 hours as needed.
Take ketoprofen precisely as directed; avoid exceeding or reducing the dosage frequency indicated by your doctor or stated on the label.
To mitigate stomach upset, ketoprofen may be taken with food or milk. Your doctor might also advise taking ketoprofen with an antacid to alleviate stomach discomfort.
Your doctor will likely initiate you on an average dose of prescription ketoprofen and may adjust the dosage based on your response to the medication and any encountered side effects. Follow these instructions meticulously.
Discontinue nonprescription ketoprofen and contact your doctor if your symptoms worsen, if you develop new or unexpected symptoms, if the affected area becomes red or swollen, if your pain persists for more than 10 days, or if your fever persists for more than 3 days.
Side Effects
Some side effects may occur that usually do not need medical attention:
- constipation
- diarrhea
- sores in the mouth
- headache
- dizziness
- nervousness
- drowsiness
- difficulty falling asleep or staying asleep
- ringing in the ears
Inform your healthcare provider immediately if you experience any serious side effects:
- changes in vision
- unexplained weight gain
- shortness of breath or difficulty breathing
- swelling of the abdomen, feet, ankles, or lower legs
- fever
- blisters
- rash
- itching
- hives
- swelling of the eyes, face, lips, tongue, throat, arms, or hands
- hoarseness
- difficulty swallowing
- excessive tiredness
- unusual bleeding or bruising
- lack of energy
- loss of appetite
- nausea
- pain in the upper right part of the stomach
- flu-like symptoms
- yellowing of the skin or eyes
- pale skin
- fast heartbeat
- cloudy, discolored, or bloody urine
- back pain
- difficult or painful urination
Caution
- Before starting ketoprofen, inform your doctor or pharmacist if you have any allergies, particularly to ketoprofen, aspirin, or other NSAIDs such as ibuprofen, naproxen, or celecoxib. This product may contain inactive ingredients that could trigger allergic reactions or other complications.
- Prior to using this medication, disclose your medical history to your doctor or pharmacist, especially if you have asthma, bleeding or clotting disorders, blood disorders like anemia, nasal polyps, heart disease, high blood pressure, liver disease, stroke, swelling (edema), or gastrointestinal problems like bleeding, heartburn, or ulcers.
- Kidney problems may arise with the use of NSAID medications like ketoprofen. The risk is higher if you are dehydrated, have heart failure or kidney disease, are an older adult, or take certain medications. Stay hydrated as directed by your doctor and promptly report any unusual changes in urine color or amount to your doctor, such as pink or bloody urine.
- Ketoprofen may induce dizziness, drowsiness, or blurred vision. Alcohol or marijuana can exacerbate these effects. Refrain from driving, operating machinery, or engaging in tasks requiring alertness until you can do so safely.
- This medication may increase the risk of stomach bleeding. Combining daily alcohol and tobacco use with this medication may further elevate the risk. Limit alcohol intake and consider quitting smoking. Seek advice from your doctor or pharmacist regarding safe alcohol consumption.
- Ketoprofen may heighten sensitivity to sunlight. Minimize sun exposure, avoid tanning booths and sunlamps, and utilize sunscreen and protective clothing when outdoors. Notify your doctor immediately if you experience sunburn or skin blisters/redness.
- Older adults may be at greater risk for stomach or intestinal bleeding, kidney problems, heart attack, and stroke while using this medication.
- Women of childbearing age should discuss the benefits and risks of ketoprofen with their doctors before use. Inform your doctor if you are pregnant or planning to become pregnant. This medication may harm an unborn baby and complicate normal labor and delivery. It is not recommended for use in pregnancy after 20 weeks until delivery. If deemed necessary by your doctor between 20 and 30 weeks of pregnancy, use the lowest effective dose for the shortest duration possible. Avoid using this medication after 30 weeks of pregnancy.
- This medication passes into breast milk. Consult your doctor before breastfeeding.
Form and Strength
Orudis SR is available in the following forms and strengths:
- ketoprofen SR extended-release tablet:
- 200 mg
FAQ
How long does it take Orudis SR to work?
The immediate-release capsule starts working as quickly as 30 minutes after you take it. The extended-release capsule can take 2 to 3 hours after you take it to start kicking in.
Does Orudis SR make you sleepy?
Drowsiness is a possible side effect of Orudis SR. Avoid driving, operating heavy machinery, or doing anything that requires alertness until you know how this medication affects you.
Resources
- https://www.goodrx.com/ketoprofen/what-is#faqs
- https://www.mayoclinic.org/drugs-supplements/ketoprofen-oral-route/description/drg-20069709#:~:text=Ketoprofen%20is%20a%20nonsteroidal%20anti,Capsule%2C%20Extended%20Release
- https://www.rxlist.com/orudis-drug.htm
- https://www.webmd.com/drugs/2/drug-9387/orudis-oral/details
- https://medlineplus.gov/druginfo/meds/a686014.html
- https://www.drugs.com/mtm/ketoprofen.html
