Prinzide (Lisinopril/Hctz) Customer Reviews


Rx Prescription Required    RxFormulation : Tablet

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The combination of lisinopril and hydrochlorothiazide is employed for the management of elevated blood pressure. Lisinopril belongs to the class of medications known as angiotensin-converting enzyme (ACE) inhibitors. It operates by reducing specific chemicals that constrict blood vessels, thereby facilitating smoother blood flow. Hydrochlorothiazide falls under the category of diuretics, commonly referred to as ‘water pills.’ This medication functions by prompting the kidneys to eliminate surplus water and salt from the body, expelling them through urine.

Uses and Dosage

The combination of lisinopril and hydrochlorothiazide is presented in tablet form for oral consumption. It is typically ingested once daily, with or without food. To ensure consistent adherence, take lisinopril and hydrochlorothiazide at approximately the same time each day.

Adhere to the prescribed dosage of lisinopril and hydrochlorothiazide precisely. Do not alter the dosage, take more or less than instructed, or exceed the frequency directed by your healthcare professional.

While lisinopril and hydrochlorothiazide effectively controls high blood pressure, it does not offer a cure. Even if you feel well, continue taking lisinopril and hydrochlorothiazide as prescribed. Do not discontinue usage without consulting your doctor.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • dizziness
  • headache
  • cough
  • excessive tiredness
  • pain, burning, or tingling in the hands or feet
  • decrease in sexual ability
  • heartburn

Inform your healthcare provider immediately if you experience any serious side effects:

  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • hoarseness
  • difficulty breathing or swallowing
  • stomach pain
  • upset stomach
  • vomiting
  • fever, sore throat, chills, and other signs of infection
  • muscle pain, cramps, or weakness
  • yellowing of the skin or eyes
  • dry mouth
  • thirst
  • weakness
  • restlessness
  • confusion
  • seizures


Before using this product, ensure to inform your doctor or pharmacist about any allergies you have, including allergies to lisinopril, hydrochlorothiazide, or other ACE inhibitors like captopril and benazepril. Inactive ingredients in this product may trigger allergic reactions or other issues.

Prior to using this medication, disclose your medical history to your doctor or pharmacist, particularly if you have a history of angioedema due to allergic reactions, have undergone blood filtering procedures such as LDL apheresis or dialysis, have received desensitizing treatment for bee/wasp sting allergy, suffer from gout, lupus, kidney disease, liver disease, or have a history of skin cancer.

This drug can induce dizziness. Combining it with alcohol or marijuana may intensify this effect. Activities requiring alertness, such as driving or using machinery, should be avoided until you can safely perform them.

Prolonged instances of severe sweating, diarrhea, or vomiting can lead to lightheadedness or dehydration. Inform your doctor of any extended episodes of diarrhea or vomiting. To prevent dehydration, maintain adequate fluid intake unless otherwise directed by your doctor.

If you have diabetes, this product might affect your blood sugar levels. Regularly monitor your blood sugar as instructed and share the results with your doctor. Adjustments to your diabetes medication, exercise routine, or diet may be necessary.

This medication can heighten sun sensitivity and elevate the risk of skin cancer, particularly with prolonged use. Minimize sun exposure, avoid tanning booths and sunlamps, and use protective clothing and sunscreen when outdoors. Notify your doctor if you experience sunburn, skin blisters/redness, or notice new or altered moles/skin lesions.

This product can influence your potassium levels. Prior to using potassium supplements or salt substitutes containing potassium, consult your doctor or pharmacist.

Elderly individuals are more susceptible to side effects of this medication, notably dizziness and changes in urine output indicating kidney problems.

If you are pregnant or planning pregnancy, inform your doctor. Using lisinopril/hydrochlorothiazide while pregnant is not recommended, as it may harm an unborn baby. Discuss the potential risks and benefits of this medication with your doctor.

It’s uncertain if lisinopril passes into breast milk. Although hydrochlorothiazide enters breast milk, it’s unlikely to harm a nursing infant. Consult your doctor before breastfeeding.

Form and Strength

Prinzide is available in the following forms and strengths:

  • lisinopril and hydrochlorothiazide tablet:

    • 10/12.5mg


How long does it take for Prinzide to work?

It may take up to 2 to 4 weeks to see the full benefits of the medication.

Is it better to take Prinzide in the morning or at night?

Your doctor may suggest that you take your first dose before bedtime because it can make you dizzy. After the very first dose, you can take lisinopril at any time of day.



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Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Prinzide (Lisinopril/Hctz). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Prinzide (Lisinopril/Hctz).