Proamatine (Midodrine) Customer Reviews


Rx Prescription Required    RxFormulation : Scored Tablet

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Rx Prescription Required    RxFormulation : Scored Tablet

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Midodrine is employed for the treatment of orthostatic hypotension, which is characterized by a sudden drop in blood pressure upon assuming a standing position. Classified as an alpha-adrenergic agonist, midodrine functions by inducing the constriction of blood vessels, leading to elevated blood pressure.

Uses and Dosage

Administer this medication orally, with or without food, in accordance with your doctor’s guidance, typically three times a day (with intervals of at least 3 to 4 hours between doses). Adhere closely to your doctor’s instructions.

This medication is intended for daytime consumption when individuals are frequently in an upright position. Avoid taking this medicine after your evening meal or less than 4 hours prior to bedtime. If you plan to recline for an extended period, such as taking a nap, it is not advisable to take your dose.

The prescribed dosage is contingent on your medical condition and response to treatment. Normally, your doctor will initiate treatment with a low dose, progressively increasing it to mitigate potential side effects. Refrain from elevating your dose or taking it more frequently than directed.

Consistently use this medication to maximize its benefits. To assist with remembering, take it at the same time(s) each day.

Inform your doctor if your condition persists or worsens. This medication should only be continued for those individuals whose symptoms improve during the course of treatment.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • numbness and tingling
  • scalp itching
  • goosebumps
  • chills
  • frequent urination
  • urgent need to urinate
  • difficulty urinating
  • rash
  • stomach pain

Inform your healthcare provider immediately if you experience any serious side effects:

  • slow heartbeat
  • dizziness
  • fainting


Prior to taking midodrine, inform your healthcare provider or pharmacist if you have any allergies, including allergies to this medication. Inactive components within the product may trigger allergic reactions or other adverse effects.

Prior to using this medication, provide your doctor with a comprehensive medical history, encompassing conditions such as hypertension, pheochromocytoma, hyperthyroidism (overactive thyroid), difficulties with urination, heart conditions, liver issues, kidney problems, and diabetes.

Exercise caution and rise gradually from seated or reclined positions to minimize the risk of dizziness upon standing.

This medication could occasionally induce dizziness, drowsiness, or blurred vision. Alcohol or marijuana may intensify these effects. Until you can perform these tasks safely, refrain from activities requiring alertness or clear vision, such as driving or operating machinery.

Notify your doctor if you are pregnant or intend to become pregnant. While using midodrine, pregnancy should be avoided, as it could potentially harm an unborn baby. If you suspect you are pregnant or become pregnant, engage with your doctor to discuss the associated risks and benefits of this medication.

The extent to which this medication passes into breast milk is unknown. Prior to breastfeeding, seek advice from your doctor.

Form and Strength

Proamatine is available in the following forms and strengths:

  • midodrine tablet:

    • 2.5mg
    • 5mg
    • 10mg


How long does Proamatine take to work?

Taking one 10 mg tablet of Proamatine while standing can raise the systolic blood pressure by about 15 mmHg to 30 mmHg after an hour. The blood-pressure-raising effects of the medication can sometimes last for up to 2 to 3 hours.

Does Proamatine cause weight gain?

Weight gain isn’t a known side effect of Proamatine.



Additional information

Generic name:



Scored Tablet, Tablet


2.5mg, 5mg, 10mg

Quantities Available:

100, 200, 300

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Proamatine (Midodrine). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Proamatine (Midodrine).