Vytorin (Ezetimibe/Simvastatin) Customer Reviews


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This combination medication is prescribed alongside a balanced diet to aid in the reduction of “bad” cholesterol and fats, such as LDL and triglycerides, while simultaneously increasing “good” cholesterol, known as HDL, in the bloodstream. Ezetimibe functions by diminishing the quantity of cholesterol your body absorbs from the foods you consume. On the other hand, Simvastatin is classified within a group of drugs called “statins,” which operate by diminishing the production of cholesterol in the liver.

Uses and Dosage

Administer this medication orally, with or without food, as instructed by your physician, typically once daily during the evening.

The prescribed dosage relies on various factors including your medical condition, response to treatment, age, and any other concurrent medications, including over-the-counter drugs and herbal supplements. Ensure that you inform both your doctor and pharmacist about all the products you are using.

The typical maximum daily dose of simvastatin in this medication is 40 milligrams. If your doctor has advised you to take more than 40 milligrams of simvastatin, adhere to the prescribed dose. However, promptly consult with your healthcare provider to discuss the potential risks and benefits associated with the higher dose.

Do not increase your dose or take this medication more frequently than prescribed. Doing so will not accelerate your recovery, and it may heighten the risk of severe side effects.

While using this medication, refrain from consuming grapefruit or grapefruit juice unless your doctor or pharmacist has confirmed its safety. Grapefruit can augment the likelihood of experiencing side effects in conjunction with this medicine. If you require further information, consult your healthcare provider or pharmacist.

If you are also taking specific medications to lower your cholesterol, ensure that you take this product either a minimum of 2 hours before or at least 4 hours after ingesting these medications. These drugs can interact with this product, impeding its complete absorption.

To maximize the benefits of this drug, take it consistently at the same time each day. Continue taking this medication even if you are feeling well. Most individuals with elevated cholesterol or triglyceride levels do not experience noticeable symptoms.

Adhere to your doctor’s guidance regarding diet and exercise while taking this medication. The full therapeutic effects of this drug may take up to 4 weeks to become evident.

Side Effects

Some side effects may occur that usually do not need medical attention:

  • Body aches or pain
  • cough
  • diarrhea
  • difficulty with moving
  • ear congestion
  • general feeling of discomfort or illness
  • headache
  • loss of voice
  • muscle aches and pains or cramping
  • muscle stiffness
  • pain in the arms or legs
  • runny or stuffy nose
  • shivering
  • sneezing
  • sore throat
  • sweating
  • swollen joints
  • trouble sleeping
  • unusual tiredness or weakness

Inform your healthcare provider immediately if you experience any serious side effects:

  • lushing
  • blisters
  • rash
  • hives
  • itching
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
  • difficulty breathing or swallowing
  • hoarseness
  • joint pain
  • sensitivity to light


Prior to initiating this product, inform your healthcare provider or pharmacist of any allergies you may have, particularly if you are allergic to ezetimibe or simvastatin, or if you have any other known allergies. This product may include inactive components capable of triggering allergic reactions or other adverse effects.

Before commencing this medication, disclose your medical history to your healthcare provider or pharmacist, with a particular focus on any history of liver disease, kidney disease, or alcohol consumption.

It is prudent to restrict your alcohol intake. The daily consumption of alcoholic beverages may heighten the risk of liver issues, especially when coupled with this product. If you require additional information, consult your doctor or pharmacist.

Elderly individuals may exhibit increased sensitivity to the potential side effects of this medication, particularly with regard to muscle-related problems.

During pregnancy, use this medication only when it is clearly essential, as it may pose a risk to an unborn baby. Deliberate the potential risks and benefits with your healthcare provider.

The passage of this medication into breast milk remains uncertain. Seek advice from your doctor prior to breast-feeding.

Form and Strength

Vytorin is available in the following forms and strengths:

  • Vytorin tablet:

    • 10/10mg
    • 10/20mg
    • 10/40mg
    • 10/80mg
  • ezetimibe and simvastatin tablet:

    • 10/20mg
    • 10/40mg
    • 10/80mg


Does Vytorin affect blood sugar?

Statins have been associated with increases in HbA1c and fasting serum glucose levels that are seen in diabetes.

Is Vytorin a good statin?

Compared with simvastatin alone, Vytorin lowers cholesterol levels more.


  1. https://www.medicinenet.com/side_effects_of_ezetimibe_and_simvastatin/side-effects.htm
  2. https://www.medicalnewstoday.com/articles/vytorin#uses
  3. https://www.mayoclinic.org/drugs-supplements/ezetimibe-and-simvastatin-oral-route/side-effects/drg-20062939?p=1
  4. https://www.webmd.com/drugs/2/drug-91445/vytorin-10-40-oral/details
  5. https://www.medicinenet.com/ezetimibe_and_simvastatin/article.htm#what_are_the_side_effects_of_ezetimibe_and_simvastatin
  6. https://www.drugs.com/vytorin.html

Additional information

Generic name:

Ezetimibe/Simvastatin, Ezetimibe/simvastatin




10/10mg, 10/20mg, 10/40mg, 10/80mg

Quantities Available:

30, 90

Can Drug Store has provided information from third parties intended to increase awareness and does not contain all the information about Vytorin (Ezetimibe/Simvastatin). Talk to your doctor or a qualified medical practitioner for medical attention, advice, or if you have any concerns about Vytorin (Ezetimibe/Simvastatin).